Rao et al., eNeuro, 2024

RhoGEF Tiam2 Regulates Glutamatergic Synaptic Transmission in Hippocampal CA1 Pyramidal Neurons

Rao et al., Molecular Autism, 2024

Detection of autism spectrum disorder-related pathogenic trio variants by a novel structure-based approach

Pushkin et al., Journal of Neuroscience, 2023

Protein 4.1N Plays a Cell Type-Specific Role in Hippocampal Glutamatergic Synapse Regulation

Kay et al., Nature Communications, 2022

Schizophrenia-associated SAP97 mutations increase glutamatergic synapse strength in the dentate gyrus and impair contextual episodic memory in rats.

Tian et al., Journal of Neuroscience, 2021

Autism Spectrum Disorder/Intellectual Disability-Associated Mutations in Trio Disrupt Neuroligin 1-Mediated Synaptogenesis.

Kay and Herring., Scientific Reports, 2021

An optogenetic method for investigating presynaptic molecular regulation

Paskus et al., Trends in Neurosciences, 2020

Kalirin and Trio: RhoGEFs in Synaptic Transmission, Plasticity, and Complex Brain Disorders

Paskus et al., Cell Reports, 2019

Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.

Rao et al., Journal of Neuroscience, 2019

Tiam1 is Critical for Glutamatergic Synapse Structure and Function in the Hippocampus.

Tian et al., Frontiers in Molecular Neuroscience, 2018

An Intellectual Disability-Related Missense Mutation in Rac1 Prevents LTP Induction.

Sadybekov and Tian et al., Nature Communications, 2017

An autism spectrum disorder-related de novo mutation hotspot discovered in the GEF1 domain of Trio

Contact Us

Principal Investigator

Bruce Herring, Ph.D.

Lab Manager

Manuel Cerpas Lua

University of Southern California

Hedco Neuroscience Building (HNB)
3641 Watt Way
Los Angeles, California 90089