Neurobiology of Risky Decision-making

We conducted a NIDA funded grant that is allowing us to examine the neural circuitry underlying risky decision making in METH and non-METH using men who have sex with men (MSM). We are using a combination of fMRI, structural MRI, diffusion tensor imaging (DTI), personality questionnaires, and computational modeling to attempt to capture the components and the neural circuit that underlies risky decision making.

We previously worked on an NIGMS funded grant on computational modeling of motivation, personality and risky decision-making. This work was done in collaboration with a group at the University of Colorado at Boulder, including Seth Herd, Randy O’Reilly, and Tom Hazy. The project attempted to build a neurobiologically based model of the major components involved in risky decision-making.

Interactive Media and Changing Risky Sexual Behavior

Lynn Miller and I had an extensive body of work over about 20 years on using Interactive Media to change risky sexual behavior in men who have sex with men.