Publications

(Updated Aug. 2022)

 

• Ojha D., Jaszczur M., Sikand A., McDonald J., Robinson A., van Oijen A.,  Mak C., Pinaud F., Cox M., Woodgate R., Goodman M. “Host cell RecA activates a mobile element-encoded mutagenic DNA polymerase”Nucleic Acid Research (2022) 50 (12) 6854–6869.

• Chong G., Pirbadian S., Zhao Y., Zacharoff L., Pinaud F., El-Naggar M.”Single molecule tracking of bacterial cell surface cytochromes reveals dynamics that impact long-distance electron transport”. PNAS (2022) 119(19) e2119964119.

• Fernandez A., Bautista M., Wu L., Pinaud F. “Emerin self-assembly and nucleoskeletal coupling regulate nuclear envelope mechanics against stress”. Journal of Cell Science(2022) 135 (6):jcs258969.

• Ahis Shrestha A., Pinaud F., Haselwandter C. “Mechanics of cup-shaped caveolae”.Physical Review E (2021) 104 (2), L022401, doi: 10.1103/PhysRevE.104.L022401.

• Lee N, Yoon C., Wang Q., Moon S., Koo K., Jung H., Chen R., Jiang L., Lu G., Fernandez A., Chow R., Weitz A., Salvaterra P., Pinaud F., Shung K. “Focused ultrasound stimulates ER localized mechanosensitive Pannexin-1 to mediate intracellular calcium release in invasive cancer cells”.Frontiers in Cell and Developmental Biology (2020) 8:504: doi: 10.3389/fcell.2020.00504.

• Zhao, Y. and Pinaud F. “In Vivo Single-Molecule Tracking of Voltage-Gated Calcium Channels with Split-Fluorescent Proteins in CRISPR-Engineered C. elegans” in: Yamamoto N., Okada Y. (eds) Single Molecule Microscopy in Neurobiology.Neuromethods, vol 154. Humana, New York, NY. (2020).

• Bautista M.,Fernandez A., Pinaud F. “A micropatterning strategy to study nuclear mechanotransduction in cells”. Micromachines(2019) 10(12), 810.

• Tseng C., Stanciauskas R., Zhang P., Woo D.,Wu K., Kelly K., Gill P., Yu M., Pinaud F., Lee A.”GRP78 regulates CD44v membrane homeostasis and cell spreading in tamoxifen-resistant breast cancer”. Life Science Alliance (2019) 2(4). pii: e201900377.  Journal Cover 
  

• Jaszczur M., Vo D., Stanciauskas R., Bertram J., Cox M., Woodgate R., Mak C., Pinaud F., Goodman M.”Conformational regulation ofEscherichia coliDNA polymerase V by RecA and ATP”. PLOS Genetics (2019) 15(2):e1007956.

• Koker T., Fernandez A., Pinaud F. “Characterization of split-fluorescent protein variants and quantitative analyses of their self-assembly process”.Scientific Reports(2018) 8:5344 doi: 10.1038/s41598-018-23625-7.

• Koker T., Tang N., Tian C., Zhang W., Wang X., Martel R., Pinaud F. “Cell imaging by targeted assembly of hot-spot SERS and photoacoustic nanoprobes using split-fluorescent protein scaffolds”. Nature Communications(2018) 9:607 doi: 10.1038/s41467-018-03046-w. 
  

• Chung T., Koker T., Pinaud F. “Gold nanorod/nanosphere clustering by split-GFP fragment assembly for tunable near-infrared SERS detections”.Optical Materials Express (2017), 7(9): 3270-3283.

• Fernandez T., Bautista M., Stanciauskas R., Chung T., Pinaud F. “Cell-shaping micropatterns for quantitative super-resolution microscopy imaging of membrane mechanosensing proteins”ACS Materials and Interfaces(2017) 9(33):27575-27586  doi: 10.102/acsami.7b09743.

• Chung T., Koker T., Pinaud F. “Split-GFP: SERS Enhancers in Plasmonic Nanocluster Probes”. Small (2016), 12(42): 5891-5901.

• Tsai YL., Zhang Y., Tsen CC., Stanciauskas R., Pinaud F., Lee A. “Characterization and Mechanism of Stress-induced Translocation of 78-kilodalton Glucose Regulated Protein (GRP78) to the Cell Surface”.The Journal of Biological Chemistry (2015), 290: 8049-8064 Journal Cover

• Zhan H., Stanciauskas R., Stigloher C., Dizon K., Jospin M., Bessereau J.L., Pinaud F. “In vivo single molecule imaging identifies altered dynamics of calcium channels in dystrophin-mutant C. elegans” Nature Communications (2014) 5:4974 doi: 10.1038/ncomms5974.    (Highlighted in Nature Methods) (Highlighted in Biophotonics Dec 2014 issue). Press releases: ScienceDaily, Eurekalert, MedicalXpress.

• Susumu K.; Oh E., Delehanty J., Pinaud, F., Gemmill K., Walper S., Breger J., Schroeder M., Stewart M., Jain V., Whitaker C., Huston A., Medintz I.”A New Family of Pyridine-Appended Multidentate Polymers As Hydrophilic Ligands For Preparing Stable Biocompatible Quantum Dots”, Chemistry of Materials (2014) 26 (18): 5327–5344.

• Pinaud F., Dahan M. “Targeting and imaging single biomolecules in living cells by complementation activated light microscopy with split-fluorescent proteins”PNAS (2011) 108: E201–E210.    (Highlighted in Nature Methods)

• Iyer G., Pinaud F., Xu J., Ebenstein Y., Li J., Dahan M., Weiss S. “Aromatic Aldehyde and Hydrazine Activated Peptide Coated Quantum Dots for Easy Bioconjugation and Live Cell Imaging”Bioconj. Chem. (2011) 22: 1006-11.

• Pinaud, F., Clarke, S., Sittner, A., Dahan, M. “Probing cellular events, one quantum dot at a time”Nat. Methods (2010) 7: 275-285.

• Clarke, S., Pinaud, F., Beutel O., You C., Piehler J., Dahan, M. “Covalent monofunctionalization of peptide-coated quantum dots for single-molecule assays”Nano Lett.(2010) 10: 2147-2154.

• You C., Wilmes S., Beutel O., Löchte S., Podoplelowa Y., Roder F., Richter C., Seine T., Schaible D., Uzé G., Clarke S., Pinaud F., Dahan M., Piehler J. “Self-controlled monofunctionalization of quantum dots for multiplexed protein tracking in live cells”Angew. Chem. Int. Ed. (2010) 49: 4108-4112.

• Pinaud, F., Michalet X., Iyer G., Margeat E., Moore HP., Weiss S. “Dynamic Partitioning of a GPI-Anchored Protein in Glycosphingolipid-Rich Microdomains Imaged by Single-Quantum Dot Tracking”Traffic (2009) 10: 691-712.  Journal Cover
  

• Pinaud, F. “Peptide-coated Quantum Dots: Applications to Biological Imaging of Single Molecules in Live Cells and Organisms”VDM Verlag Publishing Saarbrucken, Germany, (2009).

• Bentolila, L., Doose, S., Ebenstein, Y., Iyer, G., Li, J., Michalet, X., Pinaud, F., Tsay, J., Weiss, S. “Peptide-Functionalized Quantum Dots for Live Diagnostic Imaging and Therapeutic Applications, Inorganic Nanoprobes for Biological Sensing and Imaging”Artech House Publisher, Boston, Massachusetts (2009) p:45-69.

• Roullier V., Clarke S., You C., Pinaud F., Gouzer G., Schaible D., Marchi-Artzner V., Piehler J., Dahan M. “High-Affinity Labeling and Tracking of Individual Histidine-Tagged Proteins in Live Cells Using Ni(2+) Tris-nitrilotriacetic Acid Quantum Dot Conjugates”Nano Lett. (2009) 9: 1228-1234.

• Iyer G., Michalet X., Chang Y., Pinaud F., Matyas SE., Payne G., Weiss S. (2008) “High Affinity scFv-Hapten Pair as a Tool for Quantum Dot Labeling and Tracking of Single Proteins in Live Cells,”Nano Lett.(2008) 8: 4618-4623.

• Chang Y., Pinaud F., Antelman J., Weiss S. “Tracking bio-molecules in live cells using quantum dots”J. Biophotonics (2008) 1: 287-298.

• Pinaud, F., Dahan, M. “Zooming into living cells”Science (2008) 320: 187-188.

• Iyer, G., Pinaud, F., Tsay, J. M., Weiss, S. “Solubilization of quantum dots with a recombinant peptide from Escherichia coli”Small (2007) 3: 793-798.

• Pinaud F., Michalet X., Bentolila L., Tsay J., Doose S., Li J., Iyer G., Weiss S. “Advances in fluorescence imaging with quantum dot bio-probes”Biomaterials (2006) 9: 1679-87.

• Doose S., Tsay J., Pinaud F., Weiss S. “Comparison of photophysical and colloidal properties of biocompatible semiconductor nanocrystals using fluorescence correlation spectroscopy”Anal. Chem.(2005) 77: 2235-2242.

• Michalet X., Pinaud F., Bentolila L., Tsay J., Doose S., Li J., Sundaresan G., Wu A., Gambhir S. S. & Weiss S. “Quantum dots for live cells, in vivo imaging, and diagnostics”Science(2005) 307, 538-544.  Journal Cover 
  

• Tsay J. M., Doose S., Pinaud F., Weiss S. “Enhancing the photoluminescence of peptide-coated nanocrystals with shell composition and UV irradiation”J. Phys. Chem. B (2005) 109: 1669-1674.

• Pinaud F., King D., Moore H. P. & Weiss S. “Bioactivation and cell targeting of semiconductor CdSe/ZnS nanocrystals with phytochelatin-related peptides”J.Am. Chem. Soc. (2004) 126: 6115-6123.

• Michalet X., Kapanidis A., Laurence T., Pinaud F., Doose S., Pflughoefft M. & Weiss S. “The power and prospects of fluorescence microscopies and spectroscopies”Annu. Rev. Biophys. Biomol. Struct. (2003) 32: 161-182.

• Michalet X., Pinaud F., Lacoste T. D., Dahan M., Bruchez M. P., Alivisatos A. P. & Weiss S. “Properties of fluorescent semiconductor nanocrystals and their application to biological labeling”Single Molecules (2001) 2: 261-76.

• Gerion D., Pinaud F., Williams S. C., Parak W. J., Zanchet D., Weiss S. & Alivisatos, A. “Synthesis and properties of biocompatible water-soluble silica-coated CdSe/ZnS semiconductor quantum dots”J. Phys. Chem. B (2001) 105: 8861-8871.

• Dahan M., Laurence T., Pinaud F., Chemla D. S., Alivisatos A. P., Sauer M. & Weiss S. “Time-gated biological imaging by use of colloidal quantum dots”Optics Letters (2001) 26: 825-827.

• Lacoste T. D., Michalet X., Pinaud F., Chemla D. S., Alivisatos A. P. & Weiss S. “Ultrahigh-resolution multicolor colocalization of single fluorescent probes”PNAS (2000) 97: 9461-9466.