2023 Fall Semester
Syllabus
Day/Time: Monday, Wednesday, and Friday 2:00 – 2:50 PM
Location: VHE 206
Instructor: Grayson Jaggers, PhD
Office: ZHS 256
Office Hours: Wednesdays 12:45-1:45PM, Tuesday 4:00-4:50PM
Email: jaggers@usc.edu (Please allow 24 hours for a response)
Course Description
We all understand that the carbohydrates, proteins, and fats we consume provide our bodies with energy, but there are biologically-active nutritional chemicals that do not provide energy. What roles do these molecules serve in our body? By what mechanisms do they impact our health? These are the questions that we will address throughout this course.
The class will consist of a mixture of lecture and in-class discussion. Topics covered include, amino acid metabolism, lipid synthesis, and the metabolic functions of vitamins and minerals. The course will also explore the functions of biologically-active non- nutrients such as caffeine and phytochemicals. This course will reinforce the principles taught in BISC 330/312, and expand upon them as students learn the biochemical basis of nutrition’s impact on metabolic functions.
Learning Objectives
After completion of homework, in-class discussions and examinations, students should be able to effectively execute the following:
- Clear written communication of complex concepts in
- Compare and contrast biochemical regulatory
- Establish connections between the metabolism of various
- Establish connections between nutrient metabolism and nutrition-based
Prerequisite: BISC 330 (Biochemistry), BISC 312 (Molecular Biochemistry)
I. Textbook (Optional)
Stipanuck, Martha H., Caudill, Marie A. Biochemical, Physiological, and Molecular Aspects of Human Nutrition (4th Edition, 2019).
II. Description and Assessment of Assignments
Exams are typically 30% multiple-choice, and 70% written response. They will be based upon concepts discussed in lecture and homework. Any information presented outside of lecture or homework assignments will not be tested upon, unless specifically stated.
Homework contains problems that require a written response. Homework that receives full credit will be turned in before the beginning of class, and contains well-reasoned and accurate responses to the questions. Late homework will not be accepted. Exceptions can be made for students under certain circumstances.
III. Grading Breakdown
The course grade will be based upon four lecture exams and homework. Each exam will be worth 100 points (21.7% of the overall grade). There are six homework assignments worth 10 points each (totaling 13% of the overall grade).
Midterm 1: 100 points Midterm 2: 100 points
Midterm 3: 100 points Final Exam: 100 points
Homework: 60 points
Total: 460 points
Typical Grade Breakdown (Just to give you an idea, but not guaranteed):
A range: 85-100% B range: 70-84% C range: 60-69%
Attendance: Exams must be taken during the scheduled class period. Attendance in lecture is not required, but is recommended, as we will be reviewing homework as well as going over lecture material.
IV. Tentative Lecture and Exam Schedule
| Week | Date | Topic |
| 1 | 21-Aug | Intro to Nutritional Biochemistry, Review of Glycolysis and β-oxidation |
| 23-Aug | Digestion and Absorption | |
| 25-Aug | Digestion and Absorption of Carbohydrates and Protein | |
| 2 | 28-Aug | Lipid Digestion and Absorption |
| 30-Aug | Amino Acid Metabolism I | |
| 1-Sep | Amino Acid Metabolism II | |
| 3 | 4-Sep | Labor Day |
| 6-Sep | Lipid Metabolism | |
| 8-Sep | Cholesterol Synthesis and Metabolism | |
| 4 | 11-Sep | Homework Discussion |
| 13-Sep | Midterm 1 | |
| 15-Sep | Fuel Regulation and Energy Balance | |
| 5 | 18-Sep | Water-Soluble Vitamins – Niacin |
| 20-Sep | Water-Soluble Vitamins – Riboflavin & Thiamin | |
| 22-Sep | Water-Soluble Vitamins – Folate | |
| 6 | 25-Sep | Water-Soluble Vitamins – Choline |
| 27-Sep | Water-Soluble Vitamins – Vitamin C | |
| 29-Sep | Fat-Soluble Vitamins – Vitamin E | |
| 7 | 2-Oct | Fat-Soluble Vitamins – Vitamin K |
| 4-Oct | Homework Discussion | |
| 6-Oct | Midterm 2 | |
| 8 | 9-Oct | Fat-Soluble Vitamins – Vitamin A |
| 11-Oct | Fat-Soluble Vitamins – Vitamin D | |
| 13-Oct | Fall Recess | |
| 9 | 16-Oct | Mineral Metabolism – Calcium |
| 18-Oct | Mineral Metabolism – Iron | |
| 20-Oct | Homework Discussion | |
| 10 | 23-Oct | Mineral Metabolism – Iodine |
| 25-Oct | Water Balance | |
| 27-Oct | Alkaloids | |
| 11 | 30-Oct | Alkaloids |
| 1-Nov | Homework Discussion | |
| 3-Nov | Midterm 3 | |
| 12 | 6-Nov | Alcohol Metabolism |
| 8-Nov | Alcohol Metabolism | |
| 10-Nov | Polyunsaturated Fatty Acids | |
| 13 | 13-Nov | Polyphenols |
| 15-Nov | Polyphenols | |
| 17-Nov | Homework Discussion | |
| 14 | 20-Nov | Polyphenols |
| 22-Nov | Thanksgiving Break | |
| 24-Nov | Thanksgiving Break | |
| 15 | 27-Nov | Phytosterols |
| 29-Nov | Phytoestrogens | |
| 1-Dec | Homework Discussion |
Final Exam: Friday, December 8th, 2-4PM
VI. Statement on Academic Conduct and Support Systems
Academic Conduct:
Plagiarism – presenting someone else’s ideas as your own, either verbatim or recast in your own words – is a serious academic offense with serious consequences. Please familiarize yourself with the discussion of plagiarism in SCampus in Part B, Section 11, “Behavior Violating University Standards” policy.usc.edu/scampus-part-b. Other forms of academic dishonesty are equally unacceptable. See additional information
in SCampus and university policies on scientific misconduct, http://policy.usc.edu/scientific-misconduct.
Support Systems:
Student Counseling Services (SCS) – (213) 740-7711 – 24/7 on call
Free and confidential mental health treatment for students, including short-term psychotherapy, group counseling, stress fitness workshops, and crisis intervention. engemannshc.usc.edu/counseling
National Suicide Prevention Lifeline – 1 (800) 273-8255
Provides free and confidential emotional support to people in suicidal crisis or emotional distress 24 hours a day, 7 days a week. www.suicidepreventionlifeline.org
Relationship and Sexual Violence Prevention Services (RSVP) – (213) 740-4900 – 24/7 on call
Free and confidential therapy services, workshops, and training for situations related to gender-based harm. engemannshc.usc.edu/rsvp
Sexual Assault Resource Center
For more information about how to get help or help a survivor, rights, reporting options, and additional resources, visit the website: sarc.usc.edu
Office of Equity and Diversity (OED)/Title IX Compliance – (213) 740-5086
Works with faculty, staff, visitors, applicants, and students around issues of protected class. equity.usc.edu
Bias Assessment Response and Support
Incidents of bias, hate crimes and microaggressions need to be reported allowing for appropriate investigation and response. studentaffairs.usc.edu/bias-assessment– response-support
The Office of Disability Services and Programs
Provides certification for students with disabilities and helps arrange relevant accommodations. dsp.usc.edu
Student Support and Advocacy – (213) 821-4710
Assists students and families in resolving complex issues adversely affecting their success as a student EX: personal, financial, and academic. studentaffairs.usc.edu/ssa
Diversity at USC
Information on events, programs and training, the Diversity Task Force (including representatives for each school), chronology, participation, and various resources for students. diversity.usc.edu
USC Emergency Information
Provides safety and other updates, including ways in which instruction will be continued if an officially declared emergency makes travel to campus infeasible. emergency.usc.edu
USC Department of Public Safety – UPC: (213) 740-4321 – HSC: (323) 442-1000 – 24- hour emergency or to report a crime.
Provides overall safety to USC community. dps.usc.edu
End-of-Semester Evaluations
I value your thoughts on the course, and myself, as your instructor. At the end of the semester, please take time to complete the course and instructor evaluations. I am always trying to improve the course, and this is a great way for me to utilize your insight.