The Zhang lab conducts research at the interface of Chemistry, Biology and Medicine. Our work spans multiple disciplines, including synthetic organic chemistry, biochemistry, cell biology and drug design. Our lab has developed innovative and complementary approaches for discovering novel covalent ligands for protein and DNA targetsduring the past few years. Through intimate collaborations with the Bridge Institute and the Keck School of Medicine, we are currently applying these powerful approaches to the study of diverse protein families to accelerate the translational research at USC.

A figure representing a drug-like molecule modulate cellular activity.

News

August 2023 – Congratulations to Chau & the whole team on their paper being accepted at JMC! A long journey and a fantastic story!

May 2023 – Congratulations to Luna & Yida on their paper being accepted and featured on the cover of ACS Chemical Biology! 

May 2023 – Elham joined out group. Welcome! 

April 2023 – Congratulations to Chau on receiving Excellence in Graduate Student Research in the Department of Chemistry!

March 2019 – Congratulations to Arunika for winning Jay Struckhoff Memorial Award, to Amir for winning Outstanding Poster Award, and to Chau for receiving Excellence in Teaching Award at the 2019 Stauffer Dinner in the Department of Chemistry!

January 2019 – Congratulations to Renata & Bianca on passing Qualification Exam!

April 2018 – Congratulations to Renata & Bianca on passing Screening and Josh on being selected as a trainee in the Chemical Biology Interface program!

April 2018 – Congratulations to Chao for being promoted to Associate Professor! Thanks to all the group members, past and present, for their contributions.

April 2018 – Congratulations to Bianca on being awarded the NSF Graduate Fellowship!

April 2018 – Nikki officially joined our group. Welcome!

January 2018 – Congratulations to Amir & Cay on their paper being accepted at EJMC!

December 2017 – Josh officially joined our group. Welcome!

October 2017 – Congratulations to Xu, Amir & YingChu on their paper being accepted at Developmental Cell!

October 2017 – Congratulations to Amir & Cay on passing their Qualification Exams!

May 2017 – Congratulations to Feng, Alvin & Vivek on their paper being accepted at JACS!

May 2017 – Congratulations to Amir & Cay on completing their screening exams!

April 2017 – Congratulation to Alvin, Arunika & YingChu on their ACS Chemical Biology paper being accepted!

March 2017 – Congratulation to YingChu on receiving the iPIDD Award!

March 2017 – Congratulation to Alvin on receiving the Burg Teaching Felloswhip!

March 2017 – Congratulations to YingChu, Alvin and Xu on their successful PhD defense!

December 2016 – Perfect holiday gift to YingChu and Christina from JACS!

December 2016 – Bianca and Renata officially joined our group. Welcome!

August 2016 – Congratulations to Alvin on his manuscript being accepted by JACS!

June 2016 – Congratulations to YingChu on her manuscript being accepted by Genes & Cancer!

May 2016 – Congratulations to YingChu on receiving Outstanding Research Award and WiSE Fellowship!

November 2015 – Congratulations to Xu & Alvin on their manuscript being accepted by JMC!

January 2015 – It’s official now – our lab has received the NSF Career Award!

 

Openings

There are currently openings in the lab for students who are motivated and interested in pursuing graduate or postdoctoral work in Chemical Biology. Interested parties are welcome to contact Dr. Zhang via email.

Contact

Chao Zhang, Ph.D.

Associate Professor
Department of Chemistry & Loker Hydrocarbon Research Institute
University of Southern California
3430 S. Vermont Ave, TRF 114A
Los Angeles, CA 90089