Mixed-media collage representing the physical sciences, featuring a star-filled nebula, a glass globe, a layered soil sample, a futuristic quantum computer, a glowing battery, molecular structures, and mathematical equations.

Division of Mathematical and Physical Sciences

Three people working on scientific experiment through glass and gloves
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Join the Dornsife Trojan Family

From the first year on, Dornsife students of math and the physical sciences work alongside faculty on developing new methods and solutions to complex problems. Your teachers aren’t just lecturers, they’re the ones making the breakthroughs that underpin drug discovery, AI algorithms, new energy materials, quantum computing, and our fundamental knowledge of the universe.  You’ll learn to ask precise questions, test them rigorously, and connect ideas from multiple perspectives. That combination of curiosity and discipline travels well into research, industry, medicine or any field that rewards people who can reason clearly about how things work.

But the professional doors that open are only part of your Dornsife Way. That same Dornsife education, no matter what you study, nurtures a love of learning and gives it direction along the way.  Your degree, over time, pays off in a richer understanding of the world — a meaningful life built around what you value and who you show up for.

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The Dornsife Way

As the tech industry shifts to AI, it’s increasingly turning to experts working in pure math and the foundational sciences.

For the young, 20-year-old Jensen, that’s graduated now, he probably would have chosen … more of the physical sciences than the software sciences.

Jensen Huang, CEO Nvidia
Jensen portrait

If I were a student today, I’d want to learn as much as possible about [math, physics, and computer science]. They’re not just essential for understanding AI — they’re essential for thinking clearly and solving the world’s biggest challenges.

Demis Hassabis, chairman and co-founder of Google DeepMind
Demis Hassabis portrait

Excellence in Research and Teaching

    Understanding a Dynamic Planet

    USC Dornsife Earth scientists study the planet as an interconnected system, from microbial life beneath the seafloor to the dynamics of the mantle and core. The department is home to two members of the National Academy of Sciences, geophysicists Thomas Jordan and John Vidale. Its research addresses earthquake processes and risk, climate and atmospheric change, ocean health, water resources, geobiology, and the evolution of life. Headquartered at USC, the Statewide California Earthquake Center brings together researchers from academia, government, and industry to advance earthquake science and strengthen California’s resilience.

    A Legacy of Molecular Innovation

    USC Dornsife chemists investigate matter at the molecular level, connecting fundamental discovery to challenges in human health, energy, and sustainability. The department builds on the work of Nobel laureates George Olah and Arieh Warshel, a tradition of molecular innovation continued by National Academy of Engineering member Mark E. Thompson, whose pioneering research helped enable modern OLED displays. Current research spans chemical biology, synthesis, catalysis, spectroscopy, theoretical chemistry, quantum science, and advanced molecular characterization. At the Loker Hydrocarbon Research Institute, chemists are developing ways to recycle carbon dioxide into fuels and materials, while interdisciplinary centers advance drug discovery, biomolecular characterization, and nanobiophysics.

    From the Cosmos to the Quantum Realm

    USC Dornsife physicists and astronomers investigate nature across its widest range of scales, from elementary particles and quantum materials to galaxies and the evolution of the universe. Research spans high energy physics, condensed matter and atomic physics, astrophysics and cosmology, biological physics, and quantum information science, using theory, experiment, observation, and large scale computation. USC’s Center for Quantum Information Science and Technology and the West Coast’s first IBM Quantum Innovation Center, established jointly with the USC Viterbi School of Engineering, support research in quantum algorithms, error correction, devices, and simulation.

    The Foundational Language of Discovery

    Mathematics reveals the structures and patterns underlying both the natural world and modern technology. USC Dornsife mathematicians work across algebra, analysis, combinatorics, geometry and topology, probability, and statistics. These fields also provide the foundations of modern artificial intelligence, from optimization and high-dimensional geometry to the probability and statistics that govern how models learn, generalize, and quantify uncertainty. The Center for Applied Mathematical Sciences connects fundamental mathematics with emerging questions in physics, biology, engineering, finance, artificial intelligence, and data science.

    A rendering of what the Earth's inner core looks like in layers.
    Molecular model
    visual representation of quantum physics
    Abstraction of math, impossible shape with galaxy over math equations
    IBM computing lab

    The Power and Promise of Quantum Information Science

    From discovering life-saving drugs, to fortifying cybersecurity, to revealing physical properties of the universe, quantum systems hold potential for solving tremendously complex problems. At USC Dornsife, researchers create insights and methods to overcome the challenging obstacle of quantum error correction — the primary obstacle that prevents us from unleashing quantum’s power at scale.  As home of the West Coast’s first IBM Quantum Innovation Center, they have unmatched access to some of the world’s most sophisticated quantum computers that help accelerate breakthroughs and  support collaboration with industry. 

    Two Nobel Laureates in Chemistry

    Two USC Dornsife chemists have gone on to win science’s highest honor. Their discoveries changed the field enough that the Nobel committee took notice, and their influence still runs through the work happening in across academia today.

    Arieh Warshel

    Distinguished Professor of Chemistry Arieh Warshel has been on the USC Dornsife faculty since 1976. He earned the 2013 Nobel Prize in Chemistry for developing the key principles behind computer simulations that are now indispensable in the study of chemical reactions. His work essentially founded the field of computational enzymology, helping scientists model how biological molecules function at the protein level.

    Nobel Laureate Arieh Warshel

    Arieh Warshel portrait

    George Olah

    Olah was a longtime USC Dornsife chemist who held the Loker Distinguished Chair in Organic Chemistry until his death in 2017. He received the 1994 Nobel Prize in Chemistry for groundbreaking work on superacids and his discovery of carbocations, a fleeting chemical species long theorized but never confirmed until Olah found a way to study them. His research helped establish USC as a leading center of advanced hydrocarbon chemistry and paved the way for cleaner gasoline and more efficient oil refining.

    Remembering George Olah

    George Olah Portrait

    Alumni Voices

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    Aaron Lauda

    Professor of Mathematics
    Divisional Dean for Mathematical and Physical Sciences