Nancy Pedersen

Summary Statement of Research Interests

My current research efforts are focused on the etiology of chronic diseases of the elderly including dementia, Parkinson’s disease, late onset depression as well as other diseases with neuropsychiatric components in midlife such as chronic fatigue. I am also leading a program of research to study the buffering effects of genes, lifestyle and the environment on healthy aging. Key to my research is the study of comorbidity and the extent to which there are pleiotropic and epistatic effects explaining these comorbidities and associations.

Journal Article

• Karlsson, I., Bennet, A., Ploner, A., Andersson, T., Reynolds, C., Gatz, M., Pedersen, N. L. (2015). Apolipoprotein E e4 genotype and the temporal relationship between depression and dementia. Neurobiology of Aging,. (26), pp. 263-270.
• Russ, T., Gatz, M., Pedersen, N. L., Hannah, J., Wyper, G., Batty, G., Deary, I., Starr, J. (2015). Geographical variation in dementia: examining the role of environmental factors in Sweden and Scotland. Epidemiology. Vol. 26 (263-270)
• Rietveld, C., Esko, T., Davies, G., Pers, T., Turley, P., Benyamin, B., Chabris, C., Emilsson, V., Russ, T., Johnson, A., Lee, J., Leeuw, C., Marioni, R., Medland, S., Miller, M., Rostapshova, O., van der Lee, S., Vinkhuyzen, A., Amin, N., Conley, D., Derringer, J., van Duijin, C., Fehrmann, R., Franke, L., Glaeser, E., Hansell, N., Hayward, C., WGIacono, W., Ibrahim-Verbaas, C., Jaddoe, V., Karjalainen, J., Laibson, D., Lichtenstein, P., Liewald, D., Magnusson, P., Martin, N., McGue, M., McMahon, G., Pedersen, N., Pinker, S., Porteous, D., Posthuma, D., Rivadeneira, F., Smith, B., Starr, J., Tiemeier, H., Timpson, N., Trzaskowski, M., Uitterlinden, A., Verhulst, F., Ward, M., Wright, M., Davey Smith, G., Deary, I., Johannesson, M., Plomin, R., Vissche, P., Benjamin, D., Cesarini, D., Koellinger, P. (2014). Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. Proceedings of the National Academy of Sciences of the United States of America. (111), pp. 13790-13794..
• Ganna, A., Salihovic, S., Sundström, J., Broeckling, C., Hedman, A., Magnusson, P., Pedersen, N., Larsson, A., Siegbahn, A., Zilmer, M., Prenni, J., Arnlöv, J., Lind, L., Fall, T., Ingelsson, E. (2014). Large-scale metabolomic profiling identifies novel biomarkers for incident coronary heart disease. PLoS Genetics. Vol. 10
• Davies, G., Harris, S., Reynolds, C., Payton, A., Knight, H., Liewald, D., Lopez, L., Luciano, M., Gow, A., Corley, J., Henderson, R., Murray, C., Pattie, A., Fox, H., Redmond, P., Lutz, M., Chiba-Falek, O., Linnertz, C., Saith, S., Haggarty, P., McNeill, G., Ke, X., Ollier, W., Horan, M., Roses, A., Ponting, C., Porteous, D., Tenesa, A., Pickles, A., Starr, J., Whalley, L., Pedersen, N., Pendleton, N., Visscher, P., Deary, I. (2014). A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing. Molecular Psychiatry. (19), pp. 76-87.
• Pedersen, N., Christensen, K., Dahl, A., Finkel, D., Franz, C., Gatz, M., Horwitz, B., Johansson, B., Johnson, W., Kremen, W., Lyons, M., Malmberg, B., McGue, M., Neiderhiser, J., Peterson, I., Reynolds, C. (2013). IGEMS: The Consortium on interplay of genes and environment across multiple studies. Twin Research in Human Genetics. (16), pp. 481-489.

• Dobzhansky Award for lifetime accomplishments in behavior genetics, Behavior Genetics Association, 2014
• Distinguished Career Contribution to Gerontology; BSS Section of Gerontological Society of America, 2007
• James Shields Award for Outstanding Twin Research, 2007