Ehrenreich research paper among Nature Communications’ top 25 for 2023

The journal Nature Communications recently released its list of Top 25 Life and Biological Sciences Articles of 2023, citing among them a breakthrough study by USC Dornsife scientists.

The research, “Building synthetic chromosomes from natural DNA,” was published on Dec. 20, 2023, and garnered more than 10,000 views over the course of a month, according to study senior author Ian Ehrenreich, professor of biological sciences.

The study describes a new process, developed by a team that includes first author and Agilent Postdoctoral Fellow Alessandro Coradini and Ehrenreich, to assemble synthetic chromosomes that could improve production of pharmaceuticals, cancer therapies, biofuels and more.

“It has led to all sorts of new research directions and collaborations, including work to help cure rare genetic disorders that are caused by chromosomal abnormalities in the human population,” Ehrenreich said.

Nature Communications chooses its annual top 25 papers by identifying the most viewed articles published within each of seven fields of research. Data, which is normalized to account for when studies are published in the year, comes from SN Insights, a digital resource for analyzing research information such as publications, grants, clinical trials and patents.