Jonathan Stange

• T32 Postdoctoral Fellow in Neuroimaging, University of Illinois at Chicago, 2016-2017

Tenure Track Appointments

• Associate Professor of Psychology, University of Southern California, 2025 –
• Assistant Professor of Psychology, University of Southern California, 2020 – 2025
• Assistant Professor of Psychiatry, University of Illinois at Chicago, 2017 – 2020

Summary Statement of Research Interests

My lab focuses on identifying cognitive and affective processes that confer risk for depression. Our work uses neuroimaging, autonomic psychophysiology, and experimental, behavioral, and intensive longitudinal methods. A primary focus is on tracking dynamic regulation processes over time in ecologically valid “real-world” contexts, using tools such as wearable ambulatory autonomic psychophysiology and ecological momentary assessment. A second focus is on identifying the neural circuitry supporting successful affect regulation in everyday life. A third focus is on experimentally modulating potential mechanisms of successful affect regulation (e.g., using heart rate variability biofeedback). By improving our understanding of how regulation varies between individuals, as well as within people over time, our research has implications for developing person-centered metrics for detecting periods of risk, and for intervening to improve affect regulation and reduce risk for depression.

We are grateful to have received funding from the National Institute of Mental Health, the Brain and Behavior Research Foundation, the American Psychological Foundation, and the Portes Foundation and Institute of Medicine of Chicago.

For more information about my work and the lab, please visit:

About Us

Research Keywords

Mood disorders; suicide; affect regulation; flexibility; risk factors; fMRI; ambulatory assessment; psychophysiology; digital phenotyping

Contracts and Grants Awarded

• Ambulatory Phenotyping with Real-Time Indices of Discordant Affect Regulation: Exploring Opportuniti, (National Institute of Mental Health), Jonathan Stange, $3,896,471, 2023 – 2028
• From Networks to the Real World: Integrating Neural and Autonomic Processes of Loss, (National Institute of Mental Health), Jonathan Stange, $954,580, 2017 – 2022
• Probing Autonomic and Network Mechanisms of Emotion Regulation in Major Depressive Disorder, (Brain and Behavior Research Foundation (NARSAD)), Jonathan Stange, $70,000, 2018 – 2020

• (Fall 2023) PSYC 360. Psychological Disorders, MW, 10:00am – 11:50am, VPD105
• (Fall 2023) PSYC 514. Psychopathology, F, 09:00am – 12:50pm, SGM911
• (Fall 2024) PSYC 360. Psychological Disorders, MW, 10:00am – 11:50am, VPD105
• (Fall 2024) PSYC 514. Psychopathology, F, 09:00am – 12:50pm, SGM911
• (Fall 2025) PSYC 514. Psychopathology, F, 09:00am – 12:50pm, SGM911

Journal Article

• Farrukh, U., Li, J., Xu, E. P., Zapetis, S. L., Stange, J. P. (2026). Time in remission from depression predicts cognitive-affective regulation dynamics in everyday life. Journal of Clinical and Experimental Neuropsychology. Vol. 48 (2), pp. 181-193.
• Xu, E. P., Stange, J. P., Linke, J. O. (2026). Network analysis suggests working memory as a key target for facilitating subjective well-being. Journal of Affective Disorders. Vol. 392, pp. 120139.
• Minns, S., Martins-Klein, B., Zapetis, S., Xu, E. P., Li, J., Leon, G. A., Turnamian, M. R., Webb, D., Tharanipathy, A., Givens, E., Stange, J. P. (2026). When breath lifts your mood: Dynamic everyday links between breathing, affect, and emotion regulation in remitted depression. Journal of Affective Disorders. Vol. 396, pp. 120686.
• Stange, J. P., Xu, E. P., Zapetis, S. L., Li, J., Jenkins, L. M., Jimmy, J., Ye, Z., Sellery, P., Phanord, C. S., Forbes, E., Trull, T. J., Mermelstein, R. J., Ajilore, O. (2026). Neurophysiological markers of regulation success in everyday life in depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. Vol. 11 (1), pp. 58-69.
• Jayakumar, S., Xu, E. P., Minns, S. A., Zapetis, S. L., Turnamian, M. R., Li, J., Wei, M., Stange, J. P. (2026). Sadness regulation in daily life in remitted depression: Regulatory repertoire composition and affect-dependent effectiveness. Journal of Affective Disorders.
• Li, J., Xu, E. P., Zapetis, S., Phanord, C., Ye, Z., Keefe, K., Farrukh, U., Forbes, E., Trull, T., Stange, J. P. (2025). Ambulatory physiological state dynamics predict proximal behavioral markers of affect regulation in everyday life. Journal of Psychopathology and Clinical Science. Vol. 134 (8), pp. 926-934.
• Stange, J. P. (2024). Integrating dynamic psychophysiological indices across time and contexts: Elucidating mechanisms, risk markers, and intervention targets. Psychophysiology. Vol. 61 (10), pp. e14630.
• Xu, E. P., Li, J., Zapetis, S. L., Trull, T., Stange, J. P. (2024). The mind wanders to dark places: Mind-wandering catalyzes rumination in the context of negative affect and impulsivity. Emotion. Vol. 24 (8), pp. 1826-1836.
• Zapetis, S. L., Xu, E. P., Li, J., Ye, Z., Phanord, C., Trull, T., Schneider, S., Stange, J. P. (2024). Autonomic inertia as a proximal risk marker for moments of perseverative cognition in everyday life in remitted depression. Depression and Anxiety. Vol. 2024, pp. 9193159.
• McAleer, J., Stewart, L., Shepard, R., Sheena, M., Kabir, S., Swank, I., Stange, J., Leow, A., Klumpp, H., Ajilore, O. (2023). Differential effects of transcranial current type on heart rate variability during emotion regulation in internalizing psychopathologies. Journal of Affective Disorders. Vol. 327, pp. 7-14.
• Xu, E., Nguyen, L., Leibenluft, E., Stange, J., Linke, J. (2023). Meta-analysis of fractional anisotopy of the uncinate fasciculus in depression. Psychological Medicine. Vol. 53 (7), pp. 2721-2731.
• Stange, J., Li, J., Xu, E., Ye, Z., Zapetis, S., Phanord, C., Wu, J., Sellery, P., Keefe, K., Forbes, E., Mermelstein, R., Trull, T., Langenecker, S. (2023). Autonomic complexity dynamically indexes affect regulation in everyday life. Journal of Psychopathology and Clinical Science. Vol. 132 (7), pp. 847-866.
• Xu, E., Li, J., Zapetis, S., Keefe, K., Trull, T., Stange, J. (2023). Momentary impulsivity interferes with emotion regulation strategy prioritization in everyday life in remitted depression. Behaviour Research and Therapy. pp. 104424.
• Kim, J., Bessette, K., Schreiner, M., Pocius, S., Dillahunt, A., Frandsen, S., Thomas, L., Easter, R., Skerrett, K., Stange, J. P., Welsh, R., Langenecker, S., Koppelmans, V. (2022). Relations of gray matter volume to dimensional measures of cognition and affect in mood disorders. Cortex. Vol. 156, pp. 57-70.
• Langenecker, S., Schreiner, M., Thomas, L., Bessette, K., Deldonno, S., Jenkins, L., Easter, R., Stange, J., …, .., Welsh, R. (2022). Using network parcels and resting state networks to estimate correlates of mood disorder and related research domain criteria constructs of reward responsiveness and inhibitory control. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. Vol. 7 (1), pp. 76-84.
• Wu, J., Hamilton, J., Fresco, D., Alloy, L., Stange, J. (2022). Decentering predicts attenuated perseverative thought and internalizing symptoms following stress exposure: A multi-level, multi-wave study. Behaviour Research and Therapy. Vol. 152, pp. 104017.
• Stange, J. P., Jenkins, L. M., Pocius, S., Kreutzer, K., Bessette, K., DelDonno, S. R., Kling, L. R., Bhaumik, R., Welsh, R. C., Keilp, J. G., Phan, K. L., Langenecker, S. A. (2020). Using resting-state intrinsic network connectivity to identify suicide risk in mood disorders. Psychological Medicine.
• Stange, J. P., Hamilton, J. L., Shepard, R., Wu, J., Fresco, D. M., Alloy, L. B. (2020). Inflexible autonomic responses to sadness predict habitual and real-world rumination: A multi-level, multi-wave study. Biological Psychology.
• Stange, J. P., MacNamara, A., Kennedy, A. E., Hajcak, G., Phan, K. L., Klumpp, H. (2020). Brain-behavioral adaptability predicts response to cognitive behavioral therapy for emotional disorders: A person-centered event-related potential study. Neuropsychologia. Vol. 145, pp. 106408.
• Vesel, C., Rashidisabet, H., Zulueta, J., Stange, J. P., Duffecy, J., Hussain, F., Piscitello, A., Bark, J., Langenecker, S. A., Young, S., Mounts, E., Omberg, L., Nelson, P., Moore, R. C., Koziol, D., Bourne, K., Bennett, C. C., Ajilore, O., Demos, A. P., Leow, A. (2020). Effects of mood and aging on keystroke dynamics metadata and their diurnal patterns in a large open-science sample: A BiAffect iOS study. Journal of the American Medical Informatics Association. Vol. 27 (7), pp. 1007-1018.
• Stange, J. P., Kleiman, E. M., Mermelstein, R. J., Trull, T. J. (2019). Using ambulatory assessment to measure dynamic risk processes in affective disorders. Journal of Affective Disorders. Vol. 259, pp. 325-336.
• Burkhouse, K. L., Stange, J. P., Jacobs, R. H., Bhaumic, R., Bessette, K. L., Peters, A. T., Crane, N. A., Kreutzer, K. A., Fitzgerald, K., Monk, C., Welsh, R. C., Phan, K. L., Langenecker, S. A. (2019). Developmental changes in resting-state functional networks in individuals with and without internalizing psychopathologies. Depression and Anxiety. Vol. 36 (2), pp. 141-152.
• Hamilton, J. L., Stange, J. P., Burke, T. A., Franzen, P., Alloy, L. B. (2019). Sleep disturbance and physiological regulation among young adults with prior depression. Journal of Psychiatric Research. Vol. 115, pp. 75-81.
• Peters, A. T., Jenkins, L. M., Stange, J. P., Bessette, K. L., Skerrett, K. A., Kling, L. R., Welsh, R., Milad, M., Phan, K. L., Langenecker, S. A. (2019). Pre-scan cortisol is differentially associated with enhanced cross-network connectivity to the cognitive control network in young adults with a history of depression. Psychoneuroendocrinology. Vol. 104, pp. 219-227.
• Stange, J. P., Zulueta, J., Langenecker, S. A., Ryan, K. A., Piscitello, A., Duffecy, J., McInnis, M. G., Nelson, P., Ajilore, O., Leow, A. (2018). Let your fingers do the talking: Passive typing instability predicts future mood outcomes. Bipolar Disorders. Vol. 20 (3), pp. 285-288.
• Stange, J. P., Jenkins, L. M., Bessette, K. L., Kling, L. R., Bark, J. S., Shepard, R., Hamlat, E. J., DelDonno, S., Phan, K. L., Passarotti, A. M., Ajilore, O., Langenecker, S. A. (2018). Predictors of attrition in longitudinal neuroimaging research: Inhibitory control, head movement, and resting-state functional connectivity. Brain Connectivity. Vol. 8 (9), pp. 527-536.
• Stange, J. P., Jenkins, L. M., Hamlat, E. J., Bessette, K. L., DelDonno, S., Kling, L. R., Passarotti, A. M., Phan, K. L., Klumpp, H., Ryan, K. A., Langenecker, S. A. (2018). Disrupted engagement of networks supporting hot and cold cognition in remitted major depressive disorder. Journal of Affective Disorders. Vol. 227, pp. 183-191.
• Quinn, M. E., Stange, J. P., Jenkins, L. M., Corwin, S., DelDonno, S. R., Bessette, K. L., Welsh, R. C., Langenecker, S. A. (2018). Cognitive control impairment and resting state networks disruption in remitted major depressive disorder: An early developmental correlate of childhood adversity. Social Cognitive Affective Neuroscience. Vol. 13 (10), pp. 1081-1090.
• Mac Giollabhui, N., Hamilton, J. L., Nielsen, J., Connolly, S. L., Stange, J. P., Varga, S., Burdette, S., Olino, T. M., Abramson, L. Y. (2018). Negative cognitive style interacts with negative life events to predict first onset of a major depressive episode in adolescence via hopelessness. Journal of Abnormal Psychology. Vol. 127 (1), pp. 1-11.
• Stange, J. P., Bessette, K. L., Jenkins, L., Peters, A. T., Feldhaus, C., Crane, N. A., Ajilore, O., Jacobs, R. H., Watkins, E. R., Langenecker, S. A. (2017). Attenuated intrinsic connectivity within cognitive control network among individuals with remitted depression: Temporal stability and association with negative cognitive styles. Human Brain Mapping. Vol. 38 (6), pp. 2939-2954.
• Stange, J. P., Alloy, L. B., Fresco, D. M. (2017). Inflexibility and vulnerability to depression: A systematic qualitative review. Clinical Psychology: Science and Practice. Vol. 24 (3), pp. 245-276.
• Stange, J. P., Hamilton, J. L., Olino, T. M., Fresco, D. M., Alloy, L. B. (2017). Autonomic reactivity and vulnerability to depression: A multi-wave study. Emotion. Vol. 17 (4), pp. 602-615.
• Stange, J. P., Hamilton, J. L., Fresco, D. M., Alloy, L. B. (2017). Flexible parasympathetic responses to sadness facilitate spontaneous affect regulation. Psychophysiology. Vol. 54 (7), pp. 1054-1069.
• Stange, J. P., Hamilton, J. L., Fresco, D. M., Alloy, L. B. (2017). Perseverate or decenter? Differential effects of metacognition on the relationship between parasympathetic inflexibility and symptoms of depression in a multi-wave study. Behaviour Research and Therapy. Vol. 97, pp. 123-133.
• Stange, J. P., MacNamara, A., Barnas, O., Kennedy, A. E., Hajcak, G., Phan, K. L., Klumpp, H. (2017). Neural markers of attention to aversive pictures predict response to cognitive behavioral therapy in anxiety and depression. Biological Psychology. Vol. 123, pp. 269-277.
• Jenkins, L., Stange, J. P., Barba, A., DelDonno, S., Kling, L., Briceno, E., Weisenbach, S., Phan, K. L., Shankman, S., Welsh, R. C., Langenecker, S. A. (2017). Integrated cross-network connectivity of amygdala, insula and subgenual cingulate associated with facial emotion perception in healthy controls and remitted major depressive disorder. Cognitive Affective and Behavioral Neuroscience. Vol. 17 (6), pp. 1242-1254.
• Stange, J. P., Connolly, S. L., Burke, T. A., Hamilton, J. L., Hamlat, E. J., Abramson, L. Y., Alloy, L. B. (2016). Inflexible cognition predicts first onset of major depression in adolescence. Depression and Anxiety. Vol. 33 (11), pp. 1005-1012.
• Stange, J. P., Sylvia, L. G., Magalhães, P. V., Miklowitz, D. J., Otto, M. W., Frank, E., Yim, C., Berk, M., Dougherty, D. D., Nierenberg, A. A., Deckersbach, T. (2016). Affective instability and the course of bipolar depression: Results from the STEP-BD randomized, controlled trial of psychosocial treatment. British Journal of Psychiatry. Vol. 208 (4), pp. 352-358.
• Stange, J. P., Kleiman, E. M., Sylvia, L. G., Magalhães, P. V., Berk, M., Nierenberg, A. A., Deckersbach, T. (2016). Specific mood symptoms confer risk for subsequent suicidal ideation in bipolar disorder with and without suicide attempt history: Multi-wave data from STEP-BD. Depression and Anxiety. Vol. 33, pp. 464-472.

• Susan Nolen-Hoeksema Early Career Research Award, Society for a Science of Clinical Psychology , 2024 –
• Early Career Award, Society for Affective Science, 2023 –
• Distinguished Early Career Contribution to Psychophysiology Award, Society for Psychophysiological Research, 2021 –
• President’s New Researcher Award, Association for Behavioral and Cognitive Therapies, 2021 –
• New Investigator Award, American Society of Clinical Psychopharmacology, 2019 –
• Young Investigator Award, World Federation of Societies of Biological Psychiatry, 2019 –
• Emotional Health Research Excellence Prize, Macquarie University (Sydney, Australia), 2018 –
• Rising Star, Association for Psychological Science, 2018 –
• Travel Awardee, American College of Neuropsychopharmacology, 2018 –

Editorships and Editorial Boards

• Editorial Board, Frontiers in Psychiatry, 2023 –
• Editorial Board, Behavior Therapy, 2020 –
• Editorial Board, Cognitive Therapy and Research, 2019 –
• Associate Editor, International Journal of Cognitive Therapy, 2019 –

Professional Memberships

• Society for Digital Mental Health, 2022 –
• Society of Biological Psychiatry, 2019 –
• Anxiety and Depression Association of America, 2018 –
• Society for Ambulatory Assessment, 2016 –
• Society for Psychophysiological Research, 2015 –
• Society for Affective Science, 2013 –
• Association for Psychological Science, 2010 –
• Society for a Science of Clinical Psychology, 2010 –
• Society for Research in Psychopathology, 2010 –
• Association for Behavioral and Cognitive Therapies, 2009 –

Review Panels

• Society of Biological Psychiatry, Travel Award Committee, 2021 –
• Association for Behavioral and Cognitive Therapies, Program Committee, 2016 –
• Israel Science Foundation, Reviewer, 2018
• Organization for Human Brain Mapping, Program Committee, 2018