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Head of the Class
May 15, 2013

USC valedictorian Katherine Fu and salutatorians Alexander Fullman and Julia Sabo Mangione — all in USC Dornsife — will…

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Xiaojiang Chen

Professor of Biological Sciences and Chemistry

Contact Information
E-mail: xiaojiac@email.usc.edu
Phone: (213) 740-5487
Office: RRI 119A

LINKS
Detailed Lab Website
 

Education

Ph.D. Biochemistry and Molecular Biology, University of California, Davis, 1/1992
B.S. , Shihezi University, China
 

Postdoctoral Training

Postdoctoral Fellow, Harvard University, 1994-1999  
 

Academic Appointment, Affiliation, and Employment History

Professor, University of Southern California, 2006-2010  
Associate Professor, University of Southern California, 2004-2006  
Associate Professor, University of Colorado School of Medicine, 01/01/2003-01/01/2004  
Assistant Professor, University of Colorado School of Medicine, 01/01/1999-01/01/2003  
Postdoctoral Fellow, Structural Biology, Harvard University, 01/01/1994-01/01/1999  
 

Description of Research

Summary Statement of Research Interests

Dr. Xiaojiang Chen's combined expertise in molecular biology, biochemistry and X-ray crystallography enables him to study important questions in cancer biology and immunology at molecular level. He has done landmark work on tumor viruses and oncogenes, as well as important DNA/RNA transaction enzymes in helicases and deaminating mutases. His current studies focus on the following three areas: 1) Cancer biology, with emphasis on cell growth regulation through oncogenes, tumor suppressors, and DNA/RNA modifying enzymes (deaminases, helicases, polymerases); 2) Immune regulation (B, T cells) and host innate and acquired immune defenses against the infection of viruses such as HIV and HPV.
 

Research Keywords

Cancer Biology, Virology (HIV, HPV, EBV), Immunology (autoimmune, B cell humoral responses), Protein Nano-Machines, DNA replication, Structural Biology, X-ray Crystallography, Biophysics
 

Research Specialties

Biological Sciences and Chemistry, Molecular Biology, Cancer Biology, Immunology, Virology, Structural Biology, Biophysics
 

Affiliations with Research Centers, Labs, and Other Institutions

Professor Chen's Lab,http://phase22.usc.edu
 

Honors and Awards

Howard Hughes Medical Institute Junior Faculty Start-Up Award, 2000-2001  
Howard Hughes Medical Institute Postdoctoral Fellowship, 1994-1998  
University of California Tom-Shell Award for Outstanding Dissertation, 1992  
 
 
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