{"id":639,"date":"2025-04-22T09:38:06","date_gmt":"2025-04-22T16:38:06","guid":{"rendered":"https:\/\/dornsife.usc.edu\/sbc\/?page_id=639"},"modified":"2025-06-20T17:37:28","modified_gmt":"2025-06-21T00:37:28","slug":"protein-refolding","status":"publish","type":"page","link":"https:\/\/dornsife.usc.edu\/sbc\/protein-refolding\/","title":{"rendered":"Protein Refolding"},"content":{"rendered":"\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n      \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p><span style=\"font-size: 80%;\">*The rates are subject to change without prior notice.<\/span><\/p>\n<table style=\"margin-top: 0px; margin-bottom: 0px; overflow-x: auto;\" width=\"auto\">\n<tbody>\n<tr align=\"center\">\n<td><b>Services<\/b><\/td>\n<td><b>Bridge Institute<\/b><\/td>\n<td><b>USC Collaboration<\/b><\/td>\n<td><b>Non-profit org\/ Collaboration<\/b><\/td>\n<td><b>Industry\/ Collaboration<\/b><\/td>\n<\/tr>\n<tr style=\"background-color: #d0dceb;\" align=\"center\">\n<td><b>Protein Refolding<\/b><\/td>\n<td><b>$800<\/b><\/td>\n<td><b>$1000<\/b><\/td>\n<td><b>$1250<\/b><\/td>\n<td><b>$1500<\/b><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p class=\"p1\">Many proteins can form inclusion bodies, which are not soluble. The pellet containing the insoluble protein will be denatured using a strong agent like Urea or Guanidine-HCl to break up the inclusion bodies. During the refolding process the denatured protein will slowly fold back to its correct fold. We try two of the most common and effective methods available.<\/p>\n<p><strong><span data-olk-copy-source=\"MessageBody\">Please complete the <a href=\"https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2025\/06\/SBC-Service-Request-Form-A.docx\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #990000;\">Service Request Form<\/span><\/a> and email it to<\/span> <a href=\"mailto:sbc-bridge-l@maillist.usc.edu\">sbc-bridge-l@maillist.usc.edu<\/a><\/strong><\/p>\n<p><a href=\"https:\/\/dornsife.usc.edu\/sbc\/services\/\"><strong>More Available Services <span style=\"background-color: #ffcc00; padding-left: 0.2em; padding-right: 0.2em;\">\u2794<\/span><\/strong><\/a><\/p>\n\n\n\n<\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":89,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-639","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - 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