{"id":159,"date":"2024-10-31T17:39:02","date_gmt":"2024-11-01T00:39:02","guid":{"rendered":"https:\/\/dornsife.usc.edu\/sbc\/?page_id=159"},"modified":"2026-02-09T14:22:21","modified_gmt":"2026-02-09T22:22:21","slug":"home-2","status":"publish","type":"page","link":"https:\/\/dornsife.usc.edu\/sbc\/","title":{"rendered":"Welcome to Bridge Structural Biology Core"},"content":{"rendered":"\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--two-columns \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--two-columns\"\n    \n      >\n\n        \n    <div class=\"col-container\">\n        <div class=\"col-group\">\n                                          \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-828\" style=\"margin: 0; padding: 0;\" src=\"https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2025\/05\/Workflow_new1800x1800_v2.png\" alt=\"\" width=\"1800\" height=\"1800\" srcset=\"https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2025\/05\/Workflow_new1800x1800_v2.png 1800w, https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2025\/05\/Workflow_new1800x1800_v2-300x300.png 300w, https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2025\/05\/Workflow_new1800x1800_v2-1024x1024.png 1024w, https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2025\/05\/Workflow_new1800x1800_v2-150x150.png 150w, https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2025\/05\/Workflow_new1800x1800_v2-768x768.png 768w, https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2025\/05\/Workflow_new1800x1800_v2-1536x1536.png 1536w, https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2025\/05\/Workflow_new1800x1800_v2-320x320.png 320w, https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2025\/05\/Workflow_new1800x1800_v2-1280x1280.png 1280w\" sizes=\"(max-width: 1800px) 100vw, 1800px\" \/><\/p>\n\n\n\n<\/div>\n                    <\/div>\n        <div class=\"col-group\">\n                                            \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>We offer a comprehensive range of services from cloning to protein expression and structure determination to support your research.<\/p>\n<div style=\"background-color: #990000; padding: 1% 3% 0 3%;\">\n<h3 style=\"color: #fff; font-size: 220%;\">Services:<\/h3>\n<\/div>\n<div style=\"background-color: #eee; padding: 3%;\">\n<ul>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/molecular-biology-cloning\/\"><strong>Molecular Biology\/ Cloning<\/strong><\/a><\/span><\/li>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><strong><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/bacterial-protein-expression\/\">Bacterial Protein Expression<\/a><\/strong><\/span><\/li>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><strong><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/protein-purification\/\">Protein Purification<\/a><\/strong><\/span><\/li>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><strong><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/protein-refolding\/\">Protein Refolding<\/a><\/strong><\/span><\/li>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><strong><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/thermal-shift-assay\/\">Thermal Shift Assay<\/a><\/strong><\/span><\/li>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><strong><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/lcp-crystallization-nt8-robot\/\">Lipid Cubic Phase (LCP) Crystallization<\/a><\/strong><\/span><\/li>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><strong><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/vd-crystallization-mosquito-robot\/\">Vapor Diffusion Crystallization<\/a><\/strong><\/span><\/li>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><strong><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/crystal-optimization\/\">Crystal Optimization<\/a><\/strong><\/span><\/li>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><strong><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/crystal-harvesting\/\">Crystal Harvesting<\/a><\/strong><\/span><\/li>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><strong><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/data-collection\/\">Data Collection<\/a><\/strong><\/span><\/li>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><strong><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/structure-determination-and-refinement\/\">Structure Determination and Refinement<\/a><\/strong><\/span><\/li>\n<li style=\"color: #990000; font-size: 120%; text-height: auto;\"><span style=\"color: #990000;\"><strong><a style=\"color: #990000;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/research-student-training\/\">Research Student Training<\/a><\/strong><\/span><\/li>\n<\/ul>\n<\/div>\n<div style=\"background-color: #990000; padding: 0.5% 3% 0.5% 6%;\">\n<p style=\"color: #ffcc00; font-size: 150%; text-align: center;\"><a style=\"color: #ffcc00;\" href=\"https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2025\/06\/SBC-Service-Request-Form-A.docx\" target=\"_blank\" rel=\"noopener\"><strong><span style=\"color: #ffcc00;\">Request a Service \u2794<\/span><\/strong><\/a><\/p>\n<\/div>\n\n\n\n<\/div>\n                    <\/div>  \n    <\/div>\n\n  <\/div><\/div>\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--two-columns \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--two-columns\"\n    \n      >\n\n        \n    <div class=\"col-container\">\n        <div class=\"col-group\">\n                                          \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Structural Biology Core at the Bridge Institute provides the essential resources and expertise needed for the structural determination of both soluble and membrane proteins. At SBC, researchers have access to state-of-the-art facilities and dedicated support from highly trained experts.<\/p>\n<p>Our team can assist with all stages of the workflow, including sample preparation, protein expression and purification, protein characterization, mutagenesis, ligand screening, crystallization, data collection, and structure determination.<\/p>\n<p>The Structural Biology Core is led by <a href=\"https:\/\/dornsife.usc.edu\/sbc\/contact-us\/\"><b>Fariborz <\/b><b>Nasertorabi<\/b><\/a> and <a href=\"https:\/\/dornsife.usc.edu\/sbc\/contact-us\/\"><b>Gye Won Han<\/b><\/a>.<\/p>\n\n\n\n<\/div>\n                    <\/div>\n        <div class=\"col-group\">\n                                            \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <div style=\"display: inline-block; background-color: #eee; width: 48%;\">\n<p style=\"background-color: #990000; padding: 3%; color: #fff;\"><strong>SBC Team<\/strong><\/p>\n<p style=\"padding-left: 5%; padding-right: 5%;\">Fariborz Nasertorabi, PhD<\/p>\n<p style=\"padding-left: 5%; padding-right: 5%;\">Gye Won Han, PhD<\/p>\n<p style=\"padding-left: 5%; padding-right: 5%;\">Jetson Lobos<\/p>\n<\/div>\n<div style=\"display: inline-block; background-color: #eee; width: 48%;\">\n<p style=\"background-color: #990000; padding: 3%; color: #fff;\"><strong>SBC Co-founders<\/strong><\/p>\n<p style=\"padding-left: 5%; padding-right: 5%;\">Ray Stevens, PhD<\/p>\n<p style=\"padding-left: 5%; padding-right: 5%;\">Vadim Cherezov, PhD<\/p>\n<p><span style=\"color: #eee; padding-left: 5%; padding-right: 5%;\">Name<\/span><\/p>\n<\/div>\n\n\n\n<\/div>\n                    <\/div>  \n    <\/div>\n\n  <\/div><\/div>\n\n\n\n\n\n  \n        \n    \n    \n        \n    \n    \n        \n    \n  \n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--interactive-content-pane \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--interactive-content-pane\"\n    \n      >\n\n    \n<div class=\"inner-wrapper\">\n  <div class=\"left\">\n              \n<div class=\"f--field f--section-title\">\n\n    \n  <h2>\n          About Using Facility:\n      <\/h2>\n\n\n<\/div>\n      \n    <div class=\"pagination-wrapper\">\n      <ul class=\"interactive-content-pane-pagination\"><\/ul>\n    <\/div>\n  <\/div>\n\n  <div class=\"right\">\n          <div class=\"swiper\">\n        <div class=\"swiper-wrapper\">\n                      <div class=\"swiper-slide\">\n              <h3 class=\"pane-title\">\n                Who Can Use the Facility\n              <\/h3>\n                                  \n<div class=\"f--field f--description\">\n\n    \n  <p>Anyone is welcome to use the facility. USC Research labs can use the provided services at a nominal cost. Nonprofit organizations and industrial collaborators outside of USC will be charged depending on services provided.<\/p>\n<p>&nbsp;<\/p>\n\n\n\n<\/div>\n                          \n  \n                              <ul>\n                                            <li>\n                                \n<div class=\"f--field f--link\">\n\n    \n    \n  \n<a \n  class=\"link\"\n  href= https:\/\/dornsife.usc.edu\/sbc\/facility\/\n    aria-label=\"Read more about More Info\"  \n>\n    More Info \n  <svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" width=\"25\" height=\"25\" xml:space=\"preserve\"><polygon fill-rule=\"evenodd\" clip-rule=\"evenodd\" fill=\"#FC0\" points=\"19.3,27.5 29.3,17.5,19.3,7.5 16.3,10.4 21.4,15.4 6.7,15.4 6.7,19.6 21.4,19.6 16.3,24.6 \"\/><\/svg>\n<\/a>\n\n\n<\/div>\n                        <\/li>\n                                    <\/ul>\n                          <\/div>\n                      <div class=\"swiper-slide\">\n              <h3 class=\"pane-title\">\n                 Collaborate with Us\n              <\/h3>\n                                  \n<div class=\"f--field f--description\">\n\n    \n  <p>We offer a wide range of services delivered by experts committed to providing fast and reliable results.\u00a0<strong>Your research is our priority\u2014we handle troubleshooting and method optimization to ensure steady progress.<\/strong><\/p>\n\n\n\n<\/div>\n                          \n  \n                              <ul>\n                                            <li>\n                                \n<div class=\"f--field f--link\">\n\n    \n    \n  \n<a \n  class=\"link\"\n  href= https:\/\/dornsife.usc.edu\/sbc\/collaborate-with-us\/\n    aria-label=\"Read more about More Info\"  \n>\n    More Info \n  <svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" width=\"25\" height=\"25\" xml:space=\"preserve\"><polygon fill-rule=\"evenodd\" clip-rule=\"evenodd\" fill=\"#FC0\" points=\"19.3,27.5 29.3,17.5,19.3,7.5 16.3,10.4 21.4,15.4 6.7,15.4 6.7,19.6 21.4,19.6 16.3,24.6 \"\/><\/svg>\n<\/a>\n\n\n<\/div>\n                        <\/li>\n                                    <\/ul>\n                          <\/div>\n                      <div class=\"swiper-slide\">\n              <h3 class=\"pane-title\">\n                Getting Started \n              <\/h3>\n                                  \n<div class=\"f--field f--description\">\n\n    \n  <p>To begin, please complete the service request form and tell us the services you are interested in. Once we receive your submission, one of our scientists will contact you shortly.<\/p>\n\n\n\n<\/div>\n                          \n  \n                              <ul>\n                                            <li>\n                                \n<div class=\"f--field f--link\">\n\n    \n    \n  \n<a \n  class=\"link\"\n  href= https:\/\/dornsife.usc.edu\/sbc\/getting-started\/\n    aria-label=\"Read more about Getting Started\"  \n>\n    Getting Started \n  <svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\" viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" width=\"25\" height=\"25\" xml:space=\"preserve\"><polygon fill-rule=\"evenodd\" clip-rule=\"evenodd\" fill=\"#FC0\" points=\"19.3,27.5 29.3,17.5,19.3,7.5 16.3,10.4 21.4,15.4 6.7,15.4 6.7,19.6 21.4,19.6 16.3,24.6 \"\/><\/svg>\n<\/a>\n\n\n<\/div>\n                        <\/li>\n                                    <\/ul>\n                          <\/div>\n                  <\/div>\n      <\/div>\n      <\/div>\n  \n<\/div>\n\n\n\n  <div class=\"background-images\">\n          <div class=\"swiper swiper-background-images\">\n        <div class=\"swiper-wrapper\">\n                      <div class=\"swiper-slide\">\n                                                                  \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img decoding=\"async\"\n                            src=\"https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-768x432.jpg\"\n          srcset=\"https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-1920x1080.jpg 1920w,https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-1280x720.jpg 1280w,https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-768x432.jpg 768w\"          sizes=\"(min-width:1200px) 75vw, (min-width:768px) 83vw, 100vw\"\n        \n                  role=\"none\"\n        \n        \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n                          <\/div>\n\n                      <div class=\"swiper-slide\">\n                                                                  \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img decoding=\"async\"\n                            src=\"https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-768x432.jpg\"\n          srcset=\"https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-1920x1080.jpg 1920w,https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-1280x720.jpg 1280w,https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-768x432.jpg 768w\"          sizes=\"(min-width:1200px) 75vw, (min-width:768px) 83vw, 100vw\"\n        \n                  role=\"none\"\n        \n        \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n                          <\/div>\n\n                      <div class=\"swiper-slide\">\n                                                                  \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img decoding=\"async\"\n                            src=\"https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-768x432.jpg\"\n          srcset=\"https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-1920x1080.jpg 1920w,https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-1280x720.jpg 1280w,https:\/\/dornsife.usc.edu\/sbc\/wp-content\/uploads\/sites\/470\/2024\/12\/white_bckr_2000x1150-768x432.jpg 768w\"          sizes=\"(min-width:1200px) 75vw, (min-width:768px) 83vw, 100vw\"\n        \n                  role=\"none\"\n        \n        \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n                          <\/div>\n\n                  <\/div>\n      <\/div>\n      <\/div>\n\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":89,"featured_media":1132,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-content-detail.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-159","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - 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