{"id":161,"date":"2023-07-27T14:17:34","date_gmt":"2023-07-27T21:17:34","guid":{"rendered":"https:\/\/dornsife.usc.edu\/pzqin-lab\/?page_id=161"},"modified":"2026-02-04T18:51:10","modified_gmt":"2026-02-05T02:51:10","slug":"publication","status":"publish","type":"page","link":"https:\/\/dornsife.usc.edu\/pzqin-lab\/publication\/","title":{"rendered":"Publication"},"content":{"rendered":"\n\n \n \n\n\n\n\n\n\n\n
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74.<\/strong> Schuster, I,, Shlipak, K.K., Qin, P.Z.<\/strong>,* (2026), \u201cImpacts of DNA Supercoiling on the Sequence-Dependent Nuclease Activity of CRISPR-Cas9 with Truncated Guides.\u201d Biochemistry<\/em>, in press.<\/a><\/p>\n

73.<\/strong> Wu, D., Snead, S., Ganguly, C., Babu, K., Li, Y., Kathiresan, V., Shen, R., Zhang, X., Rajan, R., Qin, P.Z.<\/strong>,* (2025), “Structural integrity and side-chain interaction at the loop region of the bridge helix modulate Cas9 substrate discrimination.” Nucleic Acid Res., 53, gkaf557<\/em><\/a>.<\/p>\n

72.<\/strong> \u00a0Allen, A., Cooper, B.H., Singh, J., Rohs, R., Qin, P.Z.<\/strong>,* (2025), \u201cPAM-Adjacent DNA Flexibility Tunes CRISPR-Cas12a Off-Target Binding.\u201d Sci Rep,<\/i> 15<\/span>, 4930<\/a>.<\/p>\n

71.<\/strong> \u00a0\u00a0Sun, J.-H., Wu, D. Qin, P.Z.<\/strong>, Sideris, C., (2024), “Design and Implementation of Integrated Dual-Mode Pulse and Continuous-Wave Electron Paramagnetic Resonance Spectrometers.\u201d, IEEE Trans Biomed Circuits Syst<\/em>, 18, 1209-1219<\/a>.<\/p>\n

70.<\/strong> \u00a0\u00a0 Sun, J., Rustom, M., Nguyen, T.D., Singh, J., Qin, P.Z<\/strong>., Sideris, C.*, (2024), \u201cA29.5 A Portable 14GHz Dual-Mode Pulse and Continuous-Wave Electron Paramagnetic Resonance Spectrometer Using a Subharmonic Direct Conversion Receiver,” IEEE International Solid-State Circuits Conference<\/a> (ISSCC) (conference paper)<\/em>.<\/p>\n

69.<\/strong> \u00a0\u00a0 Zhang, M., Feng, J., Li, Y., Qin, P.Z<\/strong>., and Chai, Y.*, (2024), \u201cGeneration of tamoxifen-inducible Tfap2b-CreERT2 mice using CRISPR-Cas9.\u201d Genesis,<\/em> 6, e23582<\/a>.<\/p>\n

68.<\/strong> \u00a0\u00a0 Newsom, S.N., Wang, D., Rostami, S., Schuster, I., Parameshwaran, H.P., Joseph, Y.G., Qin, P.Z<\/strong>., Liu, J.,* Rajan, R.*, (2023), \u201cDifferential divalent metal binding by SpyCas9\u2019s RuvC active site contributes to non-specific DNA cleavage.\u201d CRISPR J.<\/em>, 6, 527-542<\/a>.<\/em><\/p>\n

67<\/b>. \u00a0 Li, Y., Cooper, B. H., Liu, L., Wu, D., Zhang, X., Rohs, R., Qin, P.Z.<\/b>*; (2023) “CRISPR-Cas9 Activities with Truncated 16-Nucleotide RNA Guides Are Tuned by Target Duplex Stability Beyond the RNA\/DNA Hybrid.” Biochemistry<\/i>, 62, 2541\u20132548.<\/a><\/p>\n

66<\/b>. \u00a0\u00a0Singh, J., Liu, K.G., Jiang, W., Qin, P.Z.<\/b>*; (2023), “A DNA Unwinding Equilibrium Serves as a Checkpoint for CRISPR-Cas12a Target Discrimination.” Nucleic Acids Res.<\/i>, 51, 8730\u20138743.<\/em><\/a><\/p>\n

65<\/b>. \u00a0\u00a0 Siegel, A., Singh, J., Qin, P.Z.<\/b>*, Shan, Shu-ou* (2023), \u201cChapter 10: EPR Studies of Chaperone Interaction and Dynamics.\u201d in Biophysics of Molecular Chaperones: Function, Mechanisms and Client Protein Interactions<\/em> (ed. S. Hiller, M. Liu, and L. He, Royal Society of Chemistry), 29, 242-277.<\/a><\/p>\n

64<\/b>. \u00a0\u00a0 Hu, Y.; Wang, T.; Singh, J.; Sun, R.; Xu, L.; Niu, X.; Huang, K.; Bai, G.; Liu, G.; Zuo, X.; Chen, C.; Qin, P.Z.<\/strong>; Fang, X.*; (2022) “Phosphorothioate-Based Posttranscriptional Site-Specific Labeling of Large RNAs for Structural and Dynamic Studies.” ACS. Chem. Biol.<\/i>, 17, 2448\u20132460.<\/a><\/p>\n

63<\/b>. Li, Y., Liu, Y., Singh, J., Tangprasertchai, N.S., Trivedi, R., Fang, Y., and Qin, P.Z.<\/b>* (2022) “Site-Specific Labeling Reveals Cas9 Induces Partial Unwinding Without RNA\/DNA Pairing in Sequences Distal to the PAM.” CRISPR J.<\/i>, 5, 341-352.<\/a><\/p>\n

62<\/b>. Babu, K.; Kathiresan, V.; Kumari, P.; Newsom, S.; Parameshwaran, H. P.; Chen, X.; Liu, J.; Qin, P.Z.<\/b>*; Rajan, R.* (2021) “Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence.” Biochemistry<\/i>, 60, 3783\u20133800<\/a><\/p>\n

61<\/b>. Parameshwaran, H. P., Babu, K., Tran, C., Guan, K., Allen, A., Kathiresan, K, Qin, P.Z.<\/b>, Rajan, R.*, (2021), “Bridge helix of Cas12a imparts selectivity for cis-DNA cleavage and regulates trans-DNA cleavage.”, FEBS Lett.<\/i>, 595, 892-912<\/a><\/p>\n

60<\/b>. Wang, Y., Kathiresan, V., Chen, Y., Hu, Y., Jiang, W., Bai, G., Liu, G., Qin, P.Z.*<\/b>, Fang, X.*, (2020), “Posttranscriptional site-directed spin labeling of large RNAs with an unnatural base pair system under non-denaturing conditions.” Chem. Sci.<\/i>, 11, 9655-9664<\/a><\/p>\n

59<\/b>. Ameri, H.,* Murat, C., Arbabi, A., Jiang, W., Janga, S.R., Qin, P.Z.<\/b>, Hamm-Alvarez, S.F., (2020), “Reduced Expression of VEGF-A in Human Retinal Pigment Epithelial Cells and Human Muller Cells Following CRISPR-Cas9 Ribonucleoprotein-Mediated Gene Disruption.” Trans. Vis. Sci. Tech.<\/i> 9, 23<\/a><\/p>\n

58<\/b>. Jiang, W., Singh, J., Allen, A., Li, Y., Kathiresan, V., Qureshi, Q., Tangprasertchai, N., Zhang, X., Parameshwaran, H.P., Rajan, R., Qin, P. Z.<\/b>* (2019), \u201cCRISPR-Cas12a Nucleases Bind Flexible DNA Duplexes without RNA-DNA Complementarity.\u201d ACS Omega<\/i>, 4, 17140-17147<\/a><\/p>\n

57<\/b>. Ding, Y., Kathiresan, V., Zhang, X., Haworth, I.S.; Qin, P. Z.<\/b>* (2019), “Experimental Validation of the ALLNOX Program for Studying Protein-Nucleic Acid Complexes.” J. Phys. Chem., A<\/i>, 123, 3592-3598<\/a><\/p>\n

56<\/b>. Babu, K., Amrani, N., Jiang, W., Yogesha, S.D., Nguyen, R., Qin, P. Z.<\/b>, Rajan R.* (2019), “Bridge Helix of Cas9 Modulates Target DNA Cleavage and Mismatch Tolerance.” Biochemistry<\/i>, 58, 1905-1917<\/a><\/p>\n

55<\/b>. Shi, F., F. Kong, P. Zhao, X. Zhang, M. Chen, S. Chen, Q. Zhang, M. Wang, X. Ye, Z. Wang, Z. Qin, X. Rong, J. Su, P. Wang, Qin, P. Z.<\/b>*, and J. Du* (2018), “Single DNA Electron Spin Resonance Spectroscopy in Aqueous Solutions.” Nat. Meth.<\/i>, 15, 697\u2013699<\/a><\/p>\n

54<\/b>. Zhong, Y.-F., H. Zhang, W.-T. Liu, X.-H. Zheng, Y.-W. Zhou, Q. Cao, Y. Shen, Y. Zhao, P.Z. Qin<\/b>, L.-N. Ji, and Z.-W. Mao (2017), “A Platinum(II)-based Photosensitive Tripod as an Effective Photodynamic Anticancer Agent through DNA Damage”. Chem. Eur. J.<\/i>, 23, 16442\u201316446<\/a><\/p>\n

53<\/b>. Tangprasertchai, N.S., Di Felice, R., Zhang, X., Slaymaker, I.M., Reyes, C.V., Jiang, W., Rohs, R., and Qin, P. Z.<\/b>* (2017), \u201cCRISPR-Cas9 mediated DNA unwinding detected using site-directed spin labeling.” ACS Chem. Biol.<\/i>, 12, 1489\u20131493<\/a><\/p>\n

52<\/b>. Yang, J., Cao, Q.,* Hu, W.L., Ye, R.R., He, L., Ji, L.N., Qin, P. Z.<\/b>, and Mao, Z.W.* (2017), \u201cTheranostic TEMPO-functionalized Ru(ii) complexes as photosensitizers and oxidative stress indicators.\u201d Dalton Trans. <\/i>, 46, 445-454<\/a><\/p>\n

51<\/b>. Cao, Q., Li, Y., Freisinger, E., Qin, P. Z.<\/b>*, Sigel,R.K.O.*, and Mao, M.Z.* (2017), \u201cG-quadruplex DNA targeted metal complexes acting as potential anticancer drugs.\u201d Inorg. Chem. Front.<\/i>, 4, 10-32<\/a><\/p>\n

50<\/b>. Reyes, C.V., Tangprasertchai, N.S., Yogesha, S.D., Nguyen, R.H., Zhang, X., Rajan, R. and Qin, P. Z.<\/b>* (2017), \u201cNucleic-acid dependent conformational changes in CRISPR-Cas9 revealed by site-directed spin labeling.\u201d Cell Biochem Biophys<\/i>, 75, 203-210<\/a><\/p>\n

49<\/b>. Akiel RD, Zhang X, Abeywardana C, Stepanov V, Qin, P. Z.<\/b>*, Takahashi,S* (2016), “Investigating Functional DNA Grafted on Nanodiamond Surface Using Site-Directed Spin Labeling and Electron Paramagnetic Resonance Spectroscopy.” J. Phys. Chem. B.<\/i>, 120, 4003\u20134008<\/a><\/p>\n

48<\/b>. Xu CX, Zhang X, Zhou YW, Wang H, Cao Q, Shen Y, Ji LN, Mao ZW,* and Qin, P. Z.<\/b>* (2016), “A Nitroxide Tagged Platinum(II) Complex Enables the Identification of DNA G-quadruplex Binding Mode.” Chem. Eur. J.<\/i>, 22, 3405\u20133413<\/a><\/p>\n

47<\/b>. Zhang X, Xu CX, Di Felice R, Sponer J, Islam B, Stadlbauer P, Ding Y, Mao L, Mao ZW, and Qin, P. Z.<\/b>* (2016), “Conformations of Human Telomeric G-Quadruplex Studied Using a Nucleotide-Independent Nitroxide Label.” Biochemistry<\/i>, 55, 360\u2013372<\/a><\/p>\n

46<\/b>. Tangprasertchai, N. S., Zhang, X., Ding, Y., Tham, K., Rohs, R., Haworth, I. S., and Qin, P. Z.<\/b>* (2015), “An Integrated Spin-Labeling\/Computational-Modeling Approach for Mapping Global Structures of Nucleic Acids.” Method Enzymol. <\/i>, 564, 427-453<\/a><\/p>\n

45<\/b>. Beasley, K. N., Sutch, B.T., Hatmal, M., Langen, R., Qin, P.Z.<\/b>, Haworth, I.S.*, (2015), \u201cComputer modeling of spin labels: NASNOX, PRONOX and ALLNOX\u201d, Method Enzymol.<\/i>, 563, 569-593<\/a><\/p>\n

44<\/b>. Qin, P.Z.<\/b>, Warncke, K. (eds.), (2015), Methods Enzymol; Vol. 564<\/i><\/a>, “Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions, Part B”<\/p>\n

43<\/b>. Qin, P.Z.<\/b>, Warncke, K. (eds.), (2015), Methods Enzymol; Vol. 563<\/i><\/a>, “Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions, Part A”<\/p>\n

42<\/b>. Franck, J., Ding, Y., Stone, K., Qin, P.Z.<\/b>*, Han, S.*, (2015), \u201cAnomalously rapid hydration water diffusion dynamics found near DNA surfaces\u201d. J. Am. Chem. Soc.<\/i>, 137, 12013\u201323<\/a><\/p>\n

41<\/b>. Nguyen, P. H., Popova, A. M., Hideg, K., and Qin, P.Z.<\/b>* (2015) \u201cA nucleotide-independent cyclic nitroxide label for monitoring segmental motions in nucleic acids.\u201d BMC Biophysics<\/i>, 8: 6<\/a><\/p>\n

40<\/b>. Zheng, X.-H., Cao, Q., Ding, Y.-L., Zhong, Y.-F., Mu, G.,Qin, P.Z.<\/b>, Ji, L.-N. and Mao, Z.-W.* (2015) \u201cPlatinum(II) clovers targeting G-quadruplexes and their anticancer activities.\u201d Dalton Trans<\/i>, 44, 50\u201353 <\/a><\/p>\n

39<\/b>. Ding, Y., Nguyen, P., Tangprasertchai, N.S., Reyes, C.V., Zhang, X. and Qin, P.Z.<\/b>* (2015), “Nucleic acid structure and dynamics: perspectives from site-directed spin labeling” Electron Paramagnetic Resonance<\/i>, 24, 122\u2013147<\/a><\/p>\n

38<\/b>. Ding, Y., Zhang, X., Tham, K.W. and Qin, P.Z.<\/b>* (2014) “Experimental mapping of DNA duplex shape enabled by global lineshape analyses of a nucleotide-independent nitroxide probe.” Nucl. Acids Res.<\/i>, 42, e140<\/a><\/p>\n

37<\/b>. Xu, C.-X., Shen, Y., Hu, Q., Zheng, Y.-X., Cao, Q., Qin, P.Z.<\/b>, Zhao, Y., Ji, L.-N. and Mao, Z.-W. (2014) “Stabilization of Human Telomeric G-Quadruplex and Inhibition of Telomerase Activity by Propeller-Shaped Trinuclear Pt(II) Complexes.” Chemistry \u2013 An Asian Journal<\/i>, 9, 2519-2526<\/a><\/p>\n

36<\/b>. Zhang, X., Dantas Machado, A.C., Ding, Y., Chen, Y., Lu, Y., Duan, Y., Tham, K.W., Chen, L., Rohs, R.* and Qin, P.Z.<\/b>* (2014) “Conformations of p53 response elements in solution deduced using site-directed spin labeling and Monte Carlo sampling” Nucl. Acids Res.<\/i>, 42, 2789-2797<\/a><\/p>\n

35<\/b>. Nguyen, P., Shi, X., Sigurdsson, S.T., Herschlag, D. and Qin, P.Z.<\/b>* (2013) “A Single-Stranded Junction Modulates Nanosecond Motional Ordering of the Substrate Recognition Duplex of a Group I Ribozyme” ChemBioChem<\/i>, 14, 1720-1723<\/a><\/p>\n

34<\/b>. Chen, Y., Zhang, X., Dantas Machado, A.C., Ding, Y., Chen, Z., Qin, P.Z.<\/b>, Rohs, R. and Chen, L. (2013) “Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion” Nucl. Acids Res.<\/i>, 41, 8368-8376<\/a><\/p>\n

33<\/b>. Zhang, Xiaojun, Qin, Peter Z<\/b>,* (2013) “Studying RNA Folding Using Site-Directed Spin Labeling.” In Russell, R. (ed.), Biophysics of RNA folding<\/i>, 3, 69-87<\/a><\/p>\n

32<\/b>. Zhang, Xiaojun, Tung, Chang-Shung, Sowa, Glenna Z., Hatmal, Ma’mon M., Haworth, Ian S., Qin, Peter Z.<\/b>, (2012) “Global structure of a three-way junction in a phi29 packaging RNA dimer determined using site-directed spin labeling” J. Am. Chem. Soc.<\/i>, 134, 2644\u20132652<\/a><\/p>\n

31<\/b>. Anna M. Popova, Ma\u2019mon M. Hatmal, Maria Frushicheva, Eric A. Price, Peter Z. Qin<\/b>,* Ian S. Haworth,* (2012) “Nitroxide Sensing of a DNA Microenvironment: Mechanistic Insights from EPR Spectroscopy and Molecular Dynamics Simulations” J. Phys. Chem. B<\/i>, 116, 6387?6396<\/a><\/p>\n

30<\/b>. Phuong Nguyen, Peter Z. Qin, (2011) “RNA dynamics: perspectives from spin labels.” WIREs: RNA<\/i>, 3, 62-72<\/a><\/p>\n

29<\/b>. Zhang, Xiaojun, Lee, Sang Won, Zhao, Liang, Xia, Tianbing, Qin, Peter Z. <\/b>, (2010) “Conformational distributions at the N-peptide\/boxB RNA interface studied using site-directed spin labeling.” RNA<\/i>, 16, 2474-2483 <\/a><\/p>\n

28<\/b>. Popova, Anna M., Qin, Peter Z.<\/b>, (2010) “A nucleotide-independent nitroxide probe reports on site-specific stereomeric environment in DNA.” Biophysical Journal<\/i>, 99, 2180-2189<\/a><\/p>\n

27<\/b>. Zhang, Xiaojun, Cekan, Pavol, Sigurdsson, Snorri Th., Qin, Peter Z.<\/b>, (2009) “Studying RNA using site-directed spin-labeling and continuous-wave electron paramagnetic resonance spectroscopy.” Method Enzymol.<\/i>, 469, 303-328<\/a><\/p>\n

26<\/b>. Popova, Anna M., K\u00e1lai, Tam\u00e1s, Hideg, K\u00e1lm\u00e1n, Qin, Peter Z.<\/b>, (2009) “Site-Specific DNA Structural and Dynamic Features Revealed by Nucleotide-Independent Nitroxide Probes” Biochemistry<\/i>, 48, 8540-8550<\/a><\/p>\n

25<\/b>. Grant, Gian Paola G., Boyd, Nathan, Herschlag, Daniel, Qin, Peter Z.<\/b>, (2009) “Motions of the Substrate Recognition Duplex in a Group I Intron Assessed by Site-Directed Spin Labeling” J. Am. Chem. Soc.<\/i>, 131, 3136-3137<\/a><\/p>\n

24<\/b>. Sowa, Glenna Z., Qin, Peter Z.<\/b>, (2008) “Site-directed spin labeling studies on nucleic acid structure and dynamics.” Prog. Nucleic Acids Res. Mol. Biol.<\/i>, 82, 147-197<\/a><\/p>\n

23<\/b>. Grant, Gian Paola G., Popova, Anna, Qin, Peter Z.<\/b>, (2008) “Diastereomer characterizations of nitroxide-labeled nucleic acids” Biochem. Biophys. Res. Commun.<\/i>, 371, 451-455<\/a><\/p>\n

22<\/b>. Fang, Yun, Shu, Dan, Xiao, Feng, Guo, Peixuan, Qin, Peter Z.<\/b>, (2008) “Modular assembly of chimeric phi29 packaging RNAs that support DNA packaging” Biochem. Biophys. Res. Comm.<\/i>, 372, 589-594<\/a><\/p>\n

21<\/b>. Qin, Peter Z<\/b>, Haworth, Ian S, Cai, Qi, Kusnetzow, Ana K, Grant, Gian Paola G, Price, Eric A, Sowa, Glenna Z, Popova, Anna, Herreros, Bruno, He, Honghang, (2007) “Measuring nanometer distances in nucleic acids using a sequence-independent nitroxide probe” Nat. Protocols<\/i>, 2, 2354-2365<\/a><\/p>\n

20<\/b>. Price, Eric A., Sutch, Brian T., Cai, Qi , Qin, Peter Z.<\/b>, Haworth, Ian S., (2007) “Computation of nitroxide-nitroxide distances for spin-labeled DNA duplexes.” Biopolymers<\/i>, 87, 40-50<\/a><\/p>\n

19<\/b>. Grant, Gian Paola G., Qin, Peter Z.<\/b>, (2007) “A facile method for attaching nitroxide spin labels at the 5′ terminus of nucleic acids.” Nucl. Acids Res.<\/i>, 35, e77<\/a><\/p>\n

18<\/b>. Cai, Qi, Kusnetzow, Ana Karin, Hideg, Kalman, Price, Eric A., Haworth, Ian S., Qin, Peter Z.<\/b>, (2007) “Nanometer Distance Measurements in RNA Using Site-Directed Spin Labeling.” Biophys. J.<\/i>, 93, 2110-2117<\/a><\/p>\n

17<\/b>. Qin, P.Z.<\/b>, Jennifer, I., Oki, A., (2006) “A model system for investigating lineshape\/structure correlations in RNA site-directed spin labeling.” Biochem. Biophys. Res. Commun.<\/i>, 343, 117-124<\/a><\/p>\n

16<\/b>. Cai, Q., Kusnetzow, A.K., Hubbell, W.L., Haworth, I.S., Gacho, G.P.C., Van Eps, N., Hideg, K., Chambers, E.J., Qin, P.Z.<\/b>, (2006) “Site-directed spin labeling measurements of nanometer distances in nucleic acids using a sequence-independent nitroxide probe.” Nucl. Acids Res.<\/i>, 34, 4722-4734<\/a><\/p>\n

15<\/b>. Qin, P.Z.<\/b>, Feigon, J., Hubbell, W. L., (2005) “Site-directed spin labeling studies reveal solution conformational changes in a GAAA tetraloop receptor upon Mg2+-dependent docking of a GAAA tetraloop.” J Mol Biol<\/i>, 351, 1-8<\/a><\/p>\n

14<\/b>. Fang, Y., Cai, Q., Qin, P.Z.<\/b>, (2005) “The procapsid binding domain of phi29 packaging RNA has a modular architecture and requires 2′-hydroxyl groups in packaging RNA interaction.” Biochemistry<\/i>, 44, 9348-58<\/a><\/p>\n

[updated August, 2023]<\/p>\n\n\n\n<\/div>\n\n\n <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-content-detail.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-161","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nPublication - Peter Qin Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dornsife.usc.edu\/pzqin-lab\/publication\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publication - Peter Qin Lab\" \/>\n<meta property=\"og:url\" content=\"https:\/\/dornsife.usc.edu\/pzqin-lab\/publication\/\" \/>\n<meta property=\"og:site_name\" content=\"Peter Qin Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-05T02:51:10+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/dornsife.usc.edu\/pzqin-lab\/publication\/\",\"url\":\"https:\/\/dornsife.usc.edu\/pzqin-lab\/publication\/\",\"name\":\"Publication - 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