{"id":341,"date":"2023-07-13T12:33:50","date_gmt":"2023-07-13T19:33:50","guid":{"rendered":"https:\/\/live-usc-dornsife.pantheonsite.io\/pombenet\/?page_id=341"},"modified":"2023-07-13T12:34:03","modified_gmt":"2023-07-13T19:34:03","slug":"gene-conversion-table","status":"publish","type":"page","link":"https:\/\/dornsife.usc.edu\/pombenet\/gene-conversion-table\/","title":{"rendered":"Gene Conversion Table"},"content":{"rendered":"\n\n \n \n\n\n\n\n\n\n\n
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About this page<\/strong>: This table was intended to provide a quick translation from S. pombe to S. cerevisiae homologues prior to the genome publication and curation. It is no longer maintained but is left here because it may be helpful in some circumstances. For details and most up to date information, we suggest you go to\u00a0genedb<\/a>. There is also a group particularly interested in orthologues to which you can subscribe here:\u00a0http:\/\/publists.sanger.ac.uk\/mailman\/listinfo\/yeast_orthologous_group<\/a><\/p>\n

Fission yeast genes are listed alphabetically under just one name, but their aliases are listed alongside. If you can’t find the gene you want in its alphabetical position, use the search feature of your browser to see if it is listed under a synonym. One yeast may have a pair of genes where the other has just one. These cases are indicated by the word “and”; otherwise multiple gene names are aliases. In a few cases, the same gene designation may have been used for different genes which we have noted.<\/p>\n

Recall that just because there is a cerevisiae homologue of a pombe gene doesn’t mean they work the same way, and that genes without primary sequence homology can be functional homologues.<\/p>\n<\/div>\n<\/div>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
S. pombe gene and aliases<\/th>\nS. cerevisiae sequence homologue(s)<\/th>\nFission yeast gene product or protein function<\/th>\nMetazoan homologue? (definitely incomplete!)<\/th>\n<\/tr>\n
abp1+<\/td>\nno homologue<\/td>\nCENP-B homologue; see cbh1+ and cbh2+<\/td>\nY<\/td>\n<\/tr>\n
abt2+<\/td>\nTUB3<\/td>\nalpha tubulin (a2); not essential<\/td>\nY<\/td>\n<\/tr>\n
ade6+<\/td>\nADE2<\/td>\nphosphoribosylaminoimidazole carboxylase<\/td>\n<\/td>\n<\/tr>\n
alp2+<\/td>\nSPC97<\/td>\ngamma-tubulin interactor<\/td>\n<\/td>\n<\/tr>\n
alp4+<\/td>\nSPC98<\/td>\ngamma-tubulin interactor<\/td>\n<\/td>\n<\/tr>\n
alp6+<\/td>\nGCP3<\/td>\ngamma-tubulin interactor<\/td>\n<\/td>\n<\/tr>\n
slp16+<\/td>\nGCP6<\/td>\ngamma-tubulin interactor<\/td>\n<\/td>\n<\/tr>\n
apc10+<\/td>\nAPC10<\/td>\nAPC subunit<\/td>\nY<\/td>\n<\/tr>\n
ark1+<\/td>\nIPL1<\/td>\nAurora kinase<\/td>\nY<\/td>\n<\/tr>\n
atb2+ alp2+ ban5+ tub1+<\/td>\nTUB3<\/td>\nalpha-2 tubulin; see also nda2+<\/td>\n<\/td>\n<\/tr>\n
btf3+<\/td>\nEGD1 and BTT1<\/td>\nbinds nascent RNAs<\/td>\n<\/td>\n<\/tr>\n
byr1+ ste1+<\/td>\nSTE7<\/td>\nMAPKKK, pheromone signalling<\/td>\nY<\/td>\n<\/tr>\n
byr2+<\/td>\nSTE11<\/td>\nMAPKK, pheromone signalling<\/td>\nY<\/td>\n<\/tr>\n
byr4+<\/td>\nBYR4?<\/td>\nWith Cdc16p, a two-component GEF for the GTPase spg1 (involved in cytokinesis)<\/td>\n<\/td>\n<\/tr>\n
cbh1+<\/td>\nno homologue<\/td>\nCENP-B homologue; see cbh2+ and apb1+<\/td>\nY<\/td>\n<\/tr>\n
cbh2+<\/td>\nno homologue<\/td>\nCENP-B homologue; see cbh1+ and abp1+<\/td>\nY<\/td>\n<\/tr>\n
cdc1+<\/td>\nHYS2\/HUS2\/POL31\/SDP5<\/td>\nDNA pol delta subunit<\/td>\n<\/td>\n<\/tr>\n
cdc2+<\/td>\nCDC28<\/td>\nCDK<\/td>\nY<\/td>\n<\/tr>\n
cdc3+<\/td>\nPFY1<\/td>\nprofilin<\/td>\nY<\/td>\n<\/tr>\n
cdc4+<\/td>\nKAP122\/PDR6<\/td>\nmyosin light chain<\/td>\nY<\/td>\n<\/tr>\n
cdc5+<\/td>\nCEF1<\/td>\nMYB-type splicing factor<\/td>\nY<\/td>\n<\/tr>\n
cdc6+ pol3+ pold+<\/td>\nPOL3 \/CDC2<\/td>\nDNA polymerase delta<\/td>\nY<\/td>\n<\/tr>\n
cdc7+<\/td>\nCDC15<\/td>\nseptation kinase<\/td>\n<\/td>\n<\/tr>\n
cdc8+<\/td>\nTPM1 and TPM2<\/td>\ntropomyosin<\/td>\nY<\/td>\n<\/tr>\n
cdc10+<\/td>\nSWI6<\/td>\nG1 phase transcription factor<\/td>\n<\/td>\n<\/tr>\n
cdc11+<\/td>\nNUD1<\/td>\nrequired for cytokinesis<\/td>\n<\/td>\n<\/tr>\n
cdc12+<\/td>\nBNI1<\/td>\nrequired for actin ring assembly<\/td>\n<\/td>\n<\/tr>\n
cdc13+<\/td>\nCLB1, CLB2, CLB3, and CLB4<\/td>\nB type cyclin, M phase. Essential.<\/td>\nY<\/td>\n<\/tr>\n
cdc14+<\/td>\nno homologue<\/td>\nrequired for septation<\/td>\n<\/td>\n<\/tr>\n
cdc15+<\/td>\nHOF1\/YMR032wp<\/td>\nrequired for septation<\/td>\n<\/td>\n<\/tr>\n
cdc16+<\/td>\nBUB2<\/td>\ncheckpoint\/cytokinesis protein. With Byr4, part of the GEF for spg1<\/td>\n<\/td>\n<\/tr>\n
cdc17+<\/td>\nCDC9<\/td>\nDNA ligase<\/td>\nY<\/td>\n<\/tr>\n
cdc18+<\/td>\nCDC6<\/td>\nS phase initiator \/ MCM loader<\/td>\nY<\/td>\n<\/tr>\n
cdc20+ pol2+ pole+<\/td>\nPOL2<\/td>\npol epsiolon<\/td>\nY<\/td>\n<\/tr>\n
cdc22+<\/td>\nRNR1<\/td>\nlg subunit ribonucleotide reductase<\/td>\nY<\/td>\n<\/tr>\n
cdc23+<\/td>\nMCM10\/DNA43<\/td>\nS phase factor<\/td>\n<\/td>\n<\/tr>\n
cdc24+<\/td>\nno homologue<\/td>\nrequired for completion of S phase, possibly in Okazaki fragment maturation<\/td>\n<\/td>\n<\/tr>\n
cdc25+<\/td>\nMIH1<\/td>\nCDK tyrosine phosphatase<\/td>\nY<\/td>\n<\/tr>\n
cdc27+<\/td>\nPOL32<\/td>\nDNA pol delta subunit<\/td>\n<\/td>\n<\/tr>\n
cdc28+ prp8+<\/td>\nno homologue<\/td>\nhelicase<\/td>\n<\/td>\n<\/tr>\n
cdc45+ sna41+ goa1+<\/td>\nCDC45<\/td>\nreplication initiation factor<\/td>\nY<\/td>\n<\/tr>\n
cdm1+<\/td>\nno homologue??<\/td>\nDNA pol delta subunit<\/td>\n<\/td>\n<\/tr>\n
cds1+<\/td>\nRAD53<\/td>\ncheckpoint kinase; not essential in pombe<\/td>\nY<\/td>\n<\/tr>\n
cdt1+<\/td>\nTAH11\/SID2<\/td>\nrequired for replication initiation<\/td>\nY<\/td>\n<\/tr>\n
cek1+<\/td>\nRIM15<\/td>\nkinase<\/td>\n<\/td>\n<\/tr>\n
cgs1+<\/td>\nBCY1<\/td>\nregulatory subunit of PKA<\/td>\n<\/td>\n<\/tr>\n
cgs2+ pde1+<\/td>\nPDE1 and PDE2<\/td>\ncAMP phosphodiesterase<\/td>\n<\/td>\n<\/tr>\n
chk1+ rad27+<\/td>\nCHK1<\/td>\ncheckpoint kinase, damage response<\/td>\nY<\/td>\n<\/tr>\n
chp1+<\/td>\n?<\/td>\nchromodomain protein, required for centromere function<\/td>\n<\/td>\n<\/tr>\n
chp2+ clo2+<\/td>\nno homologue<\/td>\nchromodomain protein, related to Swi6p and HP1<\/td>\nY<\/td>\n<\/tr>\n
cig1+<\/td>\n?<\/td>\nB-type cyclin, function not clear. Not essential. See cdc13+<\/td>\n<\/td>\n<\/tr>\n
cig2+<\/td>\nCLB5 and CLB6<\/td>\nB-type cyclin in S phase, not essential. See cdc13+<\/td>\n<\/td>\n<\/tr>\n
clp1+ cfh1+ flp1+<\/td>\nCDC14<\/td>\nphosphatase, involved in septation. Not essential in pombe<\/td>\n<\/td>\n<\/tr>\n
clr1+<\/td>\nno homologue<\/td>\nDNA binding protein<\/td>\n<\/td>\n<\/tr>\n
clr3+<\/td>\nHDA1<\/td>\nhistone deacetylase<\/td>\n<\/td>\n<\/tr>\n
clr4+<\/td>\nno homologue<\/td>\nhistone H3 methyl transferase<\/td>\nY; Drosphila Su(var) 3-9<\/td>\n<\/tr>\n
clr6+<\/td>\nRPD3<\/td>\nHistone deacetylase<\/td>\nY<\/td>\n<\/tr>\n
cmb1+<\/td>\nno homologue<\/td>\nMismatch and damage recognition\/HMG protein<\/td>\n<\/td>\n<\/tr>\n
cnd1+<\/td>\nYCS4\/LOC7<\/td>\ncondensin subunit; XCAP-D2<\/td>\nY<\/td>\n<\/tr>\n
cnd2+<\/td>\nBRN1<\/td>\ncondensin subunit; XCAP-H<\/td>\nY<\/td>\n<\/tr>\n
cnd3+<\/td>\nYCG1\/TIE1\/YCS5<\/td>\ncondensin subunit; XCAP-G<\/td>\nY<\/td>\n<\/tr>\n
cnp1+<\/td>\nCSE4<\/td>\nCENP-A homologue; centromere specific H3 histone<\/td>\nY<\/td>\n<\/tr>\n
cps1+ drc1+<\/td>\nGLS1 and GLS2<\/td>\n1,3-(beta)-glucan synthase.<\/td>\n<\/td>\n<\/tr>\n
csk1+<\/td>\nCAK\/CIV1<\/td>\nCAK-activating kinase<\/td>\nY<\/td>\n<\/tr>\n
csn1+<\/td>\nno homologue<\/td>\nSignalosome subunit 1<\/td>\nY<\/td>\n<\/tr>\n
csn2+<\/td>\nno homologue<\/td>\nSignalosome subunit 2<\/td>\nY<\/td>\n<\/tr>\n
csn4+<\/td>\nno homologue<\/td>\nSignalosome subunit 4<\/td>\nY<\/td>\n<\/tr>\n
csn5+<\/td>\nRRI1<\/td>\nSignalosome subunit 5<\/td>\nY<\/td>\n<\/tr>\n
csn7+<\/td>\nno homologue<\/td>\nSignalosome subunit 7<\/td>\nY<\/td>\n<\/tr>\n
ctf18+ chl12+<\/td>\nCTF18\/CHL12<\/td>\nRFC-1 related protein required for chromosome transmission<\/td>\n<\/td>\n<\/tr>\n
ctr4+<\/td>\nCTR1 and CTR3<\/td>\nHigh affinity copper transporter<\/td>\n<\/td>\n<\/tr>\n
cuf1+<\/td>\nMAC1<\/td>\nCopper-sensing transcription factor<\/td>\n<\/td>\n<\/tr>\n
cuf2+<\/td>\nno homologue?<\/td>\nMetal ion homeostasis protein<\/td>\n<\/td>\n<\/tr>\n
cut1+<\/td>\nESP1<\/td>\npromotes anaphase. Separin.<\/td>\n<\/td>\n<\/tr>\n
cut2+<\/td>\nPDS1<\/td>\nAPC substrate, blocks cut1. Securin.<\/td>\n<\/td>\n<\/tr>\n
cut3+<\/td>\nSMC4<\/td>\ncondensin, SMC4 subunit<\/td>\nY<\/td>\n<\/tr>\n
cut4+<\/td>\nAPC1<\/td>\nAPC subunit<\/td>\nY<\/td>\n<\/tr>\n
cut6+<\/td>\nACC1<\/td>\nacetyl coA carboxylase<\/td>\n<\/td>\n<\/tr>\n
cut7+<\/td>\nCIN8 and KIP1<\/td>\nkinesin<\/td>\nY<\/td>\n<\/tr>\n
cut8+<\/td>\nDBF8<\/td>\n? regulates APC?<\/td>\n<\/td>\n<\/tr>\n
cut9+<\/td>\nCDC16<\/td>\nAPC subunit<\/td>\nY<\/td>\n<\/tr>\n
cut11+<\/td>\nNDC1<\/td>\nnuclear envelope protein at SPBs and NPCs<\/td>\n<\/td>\n<\/tr>\n
cut12+<\/td>\nno homologue<\/td>\nrequired for spindle formation<\/td>\n<\/td>\n<\/tr>\n
cut14+<\/td>\nSMC2<\/td>\ncondensin, SMC2 subunit<\/td>\nY<\/td>\n<\/tr>\n
cut17+ bir1+<\/td>\nBIR1<\/td>\nBir1\/Survivin, chromosomal passenger protein<\/td>\nY<\/td>\n<\/tr>\n
cut20+ lid1+<\/td>\nAPC4<\/td>\nAPC subunit<\/td>\nY<\/td>\n<\/tr>\n
cut23+<\/td>\nCDC23\/APC8<\/td>\nTPR-protein, APC component<\/td>\nY<\/td>\n<\/tr>\n
cyr1+ git2+<\/td>\nCYR1<\/td>\nadenylate cyclase<\/td>\n<\/td>\n<\/tr>\n
dfp1+ him1+ rad35+<\/td>\nDBF4<\/td>\nregulatory subunit of CDC7-type kinase<\/td>\nY<\/td>\n<\/tr>\n
dhc1+<\/td>\nDYN1<\/td>\ndynein motor protein<\/td>\n<\/td>\n<\/tr>\n
dim1+<\/td>\nDIB1<\/td>\nRequired for mitosis.<\/td>\n<\/td>\n<\/tr>\n
Note the designation Dim1 was used later for a different gene encoding a dimethylase.<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
dis1+<\/td>\nSTU1<\/td>\nTOG-family microtubule associated proteins (also see Mtc1\/Alp14)<\/td>\nY<\/td>\n<\/tr>\n
dis2+<\/td>\nGLC7<\/td>\nPPI-class phosphatase. Also see Sds21<\/td>\n<\/td>\n<\/tr>\n
dmc1+<\/td>\nDMC1<\/td>\nmeiosis specific Rhp51 (RAD51) homologue, presumed required for meiotic pairing<\/td>\n<\/td>\n<\/tr>\n
dna2+<\/td>\nDNA2<\/td>\nhelicase<\/td>\nY<\/td>\n<\/tr>\n
drc1+<\/td>\nDRC1\/SLD2<\/td>\nCDK target, binds Rad4\/Cut5, required for S phase.<\/td>\n<\/td>\n<\/tr>\n
<font=”-1″note that=”” the=”” name=”” drc1=”” has=”” also=”” been=”” used=”” for=”” a=”” glucan=”” synthase;=”” see=”” cps1<=”” font=””><\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
eso1+<\/td>\nCTF7\/ECO1 (C-terminal)<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
RAD30 (N-terminal)<\/td>\nRequired for sister chromatid cohesion and possibly for repair. A gene fusion: the C-terminus looks like CTF7\/ECO1, and the N-terminus looks like RAD30<\/td>\nY<\/td>\n<\/td>\n<\/tr>\n
exo1+<\/td>\nEXO1<\/td>\nMismatch repair\/5′ to 3′ exonuclease<\/td>\n<\/td>\n<\/tr>\n
git3+<\/td>\nGPR1<\/td>\nG protein coupled glucose receptors<\/td>\n<\/td>\n<\/tr>\n
gpa1+<\/td>\nGPA1<\/td>\nG protein alpha subunit in pheromone signalling<\/td>\n<\/td>\n<\/tr>\n
gtb1+<\/td>\nTUB4<\/td>\ngamma tubulin<\/td>\n<\/td>\n<\/tr>\n
hcn1+<\/td>\nCDC26<\/td>\nAPC subunit<\/td>\n<\/td>\n<\/tr>\n
hda1+ hoc1+ phd1+<\/td>\nRPD3<\/td>\nhistone deacetylase; related to clr6+<\/td>\n<\/td>\n<\/tr>\n
his1+<\/td>\nHIS1<\/td>\nATP phosphoribosyltransferase<\/td>\n<\/td>\n<\/tr>\n
his2+<\/td>\nHIS4C<\/td>\nhistidinol dehydrogenase<\/td>\n<\/td>\n<\/tr>\n
his3+<\/td>\nHIS5<\/td>\nhistidinol-phosphate aminotransferase<\/td>\n<\/td>\n<\/tr>\n
his5+<\/td>\nHIS3<\/td>\nimidazoleglycerol-phosphate dehydratase<\/td>\n<\/td>\n<\/tr>\n
his7+<\/td>\nHIS4A<\/td>\nphosphoribosyl-AMP cyclohydrase<\/td>\n<\/td>\n<\/tr>\n
hhp1+ and hhp2+<\/td>\nHRR25<\/td>\nCK-related kinases; role in repair?<\/td>\n<\/td>\n<\/tr>\n
hsk1+<\/td>\nCDC7<\/td>\nDDK: DBF4-Dependent Kinase<\/td>\nY<\/td>\n<\/tr>\n
hus1+<\/td>\nMEC3<\/td>\nCheckpoint factor, also in metazoans. Complex with rad1, 9<\/td>\nY<\/td>\n<\/tr>\n
ibp1+<\/td>\nYGR203W<\/td>\nsmall Cdc25-like phosphatase<\/td>\n?<\/td>\n<\/tr>\n
imp1+<\/td>\nSPR1<\/td>\nnuclear transport factor<\/td>\n<\/td>\n<\/tr>\n
kap104+<\/td>\nKAP104<\/td>\nnuclear transport factor<\/td>\n<\/td>\n<\/tr>\n
kap114<\/td>\nKAP114<\/td>\nnuclear transport factor<\/td>\n<\/td>\n<\/tr>\n
klp2+<\/td>\nKAR3<\/td>\nkinesin motor; redundant with pkl1+<\/td>\n<\/td>\n<\/tr>\n
klp3+<\/td>\nno homologue<\/td>\nkinesin motor<\/td>\n<\/td>\n<\/tr>\n
klp5+ and klp6+<\/td>\nKIP3<\/td>\nkinesin motors involved in MT dynamics<\/td>\n<\/td>\n<\/tr>\n
klp7+<\/td>\nno homologue<\/td>\nkinesin motor<\/td>\n<\/td>\n<\/tr>\n
klp8+<\/td>\nno homologue<\/td>\nkinesin motor<\/td>\n<\/td>\n<\/tr>\n
leu1+<\/td>\nLEU2<\/td>\nbeta-isopropylmalate dehydrogenase<\/td>\n<\/td>\n<\/tr>\n
lys1+<\/td>\nLYS2<\/td>\nalpha-aminoadipate reductase<\/td>\n<\/td>\n<\/tr>\n
mal3+<\/td>\nBIM1<\/td>\nEB1 homologue<\/td>\nY<\/td>\n<\/tr>\n
mcm2+ cdc19+ nda1+<\/td>\nMCM2<\/td>\nMCM complex subunit<\/td>\nY<\/td>\n<\/tr>\n
mcm3+<\/td>\nMCM3<\/td>\nMCM complex subunit<\/td>\nY<\/td>\n<\/tr>\n
mcm4+ cdc21+<\/td>\nMCM4\/CDC54<\/td>\nMCM complex subunit<\/td>\nY<\/td>\n<\/tr>\n
mcm5+ nda4+<\/td>\nMCM5\/CDC46<\/td>\nMCM complex subunit<\/td>\nY<\/td>\n<\/tr>\n
mcm6+ mis5+<\/td>\nMCM6<\/td>\nMCM complex subunit<\/td>\nY<\/td>\n<\/tr>\n
mcm7+<\/td>\nMCM7\/CDC47<\/td>\nMCM complex subunit<\/td>\nY<\/td>\n<\/tr>\n
mcs2+<\/td>\nCCL1<\/td>\ncyclin H, forms CAK with mcs6; essential for viability<\/td>\nY<\/td>\n<\/tr>\n
mcs4+<\/td>\nSSK1<\/td>\nresponse regulator<\/td>\n<\/td>\n<\/tr>\n
mcs6+ mop1+ crk1+<\/td>\nKIN28<\/td>\nCDK7, forms CAK (CDK-activating kinase)<\/td>\nY<\/td>\n<\/tr>\n
mdm12+<\/td>\nMDM12<\/td>\nmitochondrial morphology\/inheritance component<\/td>\n<\/td>\n<\/tr>\n
mek1+<\/td>\nMEK1<\/td>\nMeiosis-specific Cds1 (RAD53) homologue<\/td>\n<\/td>\n<\/tr>\n
mei2+<\/td>\nno homologue<\/td>\nRNA binding protein required for meiosis<\/td>\n<\/td>\n<\/tr>\n
mei3+<\/td>\nno homologue<\/td>\nactivator of meiosis: inhibits Pat1 kinase<\/td>\n<\/td>\n<\/tr>\n
meu13+<\/td>\nHOP2<\/td>\nRequired for meiotic recombination and pairing<\/td>\n<\/td>\n<\/tr>\n
mik1+<\/td>\nSWE1<\/td>\nCDK tyrosine kinase. Overlaps with wee1+; both are related to SWE1.<\/td>\n<\/td>\n<\/tr>\n
mis4+<\/td>\nSCC2<\/td>\nadherin; required for cohesin to associate with chromatin<\/td>\n<\/td>\n<\/tr>\n
mis6+<\/td>\nCTF3<\/td>\ninner centromere protein<\/td>\n<\/td>\n<\/tr>\n
mis12+<\/td>\nMTW1<\/td>\ninner centromere protein<\/td>\n<\/td>\n<\/tr>\n
mph1+<\/td>\nMPS1<\/td>\nkinase, part of spindle checkpoint<\/td>\n<\/td>\n<\/tr>\n
mpr1+ ypd1+<\/td>\nYPD1<\/td>\nresponse regulator phosphotransferase<\/td>\n<\/td>\n<\/tr>\n
mrc1+<\/td>\nMRC1<\/td>\nCheckpoint\/replication factor, works with Cds1<\/td>\nclaspin<\/td>\n<\/tr>\n
msh2+ swi8+ mut3+<\/td>\nMSH2<\/td>\nMismatch repair\/mating-type switching<\/td>\nY<\/td>\n<\/tr>\n
msh6+<\/td>\nMSH6<\/td>\nMismatch repair<\/td>\nY<\/td>\n<\/tr>\n
mst1+<\/td>\nESA1<\/td>\nMYST-family histone acetyltransferase<\/td>\nY<\/td>\n<\/tr>\n
mst2+<\/td>\nSAS2 and SAS3<\/td>\nMYST-family histone acetyltransferase<\/td>\nY<\/td>\n<\/tr>\n
mtc1+\/alp14+<\/td>\nSTU1<\/td>\nTOG-family microtubule associated proteins (also see dis1+)<\/td>\nY<\/td>\n<\/tr>\n
mts2+<\/td>\nYTA1<\/td>\nproteosome subunit<\/td>\n<\/td>\n<\/tr>\n
mts3+<\/td>\nNIN1<\/td>\nproteosome subunit<\/td>\n<\/td>\n<\/tr>\n
mus81+<\/td>\nMUS81<\/td>\ninvolved in recombination<\/td>\n<\/td>\n<\/tr>\n
nda2+<\/td>\nTUB1<\/td>\nmajor alpha tubulin<\/td>\nY<\/td>\n<\/tr>\n
nda3+<\/td>\nTUB2<\/td>\nbeta tubulin<\/td>\nY<\/td>\n<\/tr>\n
ndc80+<\/td>\nNDC80<\/td>\ncentromere-associated spindle component<\/td>\nY, human HEC<\/td>\n<\/tr>\n
nim1+ cdr1+<\/td>\nno homologue?<\/td>\nkinase regulates wee1<\/td>\n<\/td>\n<\/tr>\n
nuc2+<\/td>\nCDC27<\/td>\nAPC subunit<\/td>\nY<\/td>\n<\/tr>\n
nuf2+<\/td>\nNUF2<\/td>\ncentromere-associated spindle component<\/td>\nY<\/td>\n<\/tr>\n
nup40+<\/td>\nNUP53<\/td>\nNucleoporin<\/td>\n<\/td>\n<\/tr>\n
nup189+<\/td>\nNUP145<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
orp1+<\/td>\nORC1<\/td>\nOrigin Recognition Complex subunit<\/td>\nY<\/td>\n<\/tr>\n
orp2+<\/td>\nORC2<\/td>\nOrigin Recognition Complex subunit<\/td>\nY<\/td>\n<\/tr>\n
orp3+<\/td>\nORC3<\/td>\nOrigin Recognition Complex subunit<\/td>\nY<\/td>\n<\/tr>\n
orp4+<\/td>\nORC4<\/td>\nOrigin Recognition Complex subunit<\/td>\nY<\/td>\n<\/tr>\n
orp5+<\/td>\nORC5<\/td>\nOrigin Recognition Complex subunit<\/td>\nY<\/td>\n<\/tr>\n
orp6+<\/td>\nORC6<\/td>\nOrigin Recognition Complex subunit<\/td>\nY<\/td>\n<\/tr>\n
pat1+<\/td>\nno homologue? (loosely related to SKS1 and other PKs)<\/td>\nessential kinase inhibitor of meiosis<\/td>\n<\/td>\n<\/tr>\n
pch1+<\/td>\nno homologue?<\/td>\nC-type cyclin, essential for viability<\/td>\nY, C type cyclins<\/td>\n<\/tr>\n
pcn1+<\/td>\nPOL30<\/td>\nPCNA<\/td>\nY<\/td>\n<\/tr>\n
php2+<\/td>\nHAP2<\/td>\ncarbon-source responsive transcription factor<\/td>\n<\/td>\n<\/tr>\n
php5+<\/td>\nHAP5<\/td>\ncarbon-source responsive transcription factor<\/td>\n<\/td>\n<\/tr>\n
pic1+<\/td>\nSLI15<\/td>\nINCENP kinetochore protein<\/td>\nY<\/td>\n<\/tr>\n
pin1+<\/td>\nESS1<\/td>\nprolyl isomerase<\/td>\nY<\/td>\n<\/tr>\n
pka1+<\/td>\nTPK1, TPK2 and TPK3<\/td>\nprotein kinase A<\/td>\nY<\/td>\n<\/tr>\n
pkl1+<\/td>\nKAR3<\/td>\nkinesin motor; redundant with klp2+<\/td>\n<\/td>\n<\/tr>\n
pms1+ mlh1+<\/td>\nPMS1<\/td>\nmismatch repair protein<\/td>\nY<\/td>\n<\/tr>\n
pob1+<\/td>\nBOI1 and BOI2<\/td>\nrequired for cytokinesis<\/td>\n<\/td>\n<\/tr>\n
pol1+ swi7+ pola+<\/td>\nPOL1\/CDC17<\/td>\nDNA polymerase alpha<\/td>\nY<\/td>\n<\/tr>\n
pop1+<\/td>\nCDC4<\/td>\nlike sud1+; SCF<\/td>\n<\/td>\n<\/tr>\n
pot1+<\/td>\nno homologue?<\/td>\nprotects telomere ends<\/td>\nY<\/td>\n<\/tr>\n
ppe1+<\/td>\nSIT4<\/td>\nprotein phosphatase<\/td>\n<\/td>\n<\/tr>\n
prp2+<\/td>\nMUD2<\/td>\nlarge subunit splicing factor U2AF<\/td>\n<\/td>\n<\/tr>\n
prp4+<\/td>\nno homologue<\/td>\nkinase required for splicing<\/td>\n<\/td>\n<\/tr>\n
prp31+<\/td>\nPRP31<\/td>\nsplicing factor<\/td>\nY<\/td>\n<\/tr>\n
psm1+ smc1+<\/td>\nSMC1<\/td>\ncohesin subunit<\/td>\nY<\/td>\n<\/tr>\n
psm3+ smc3+<\/td>\nSMC3<\/td>\ncohesin subunit<\/td>\nY<\/td>\n<\/tr>\n
psc3+<\/td>\nSCC3<\/td>\ncohesin subunit<\/td>\nY<\/td>\n<\/tr>\n
puc1+<\/td>\nCLN3??<\/td>\ncyclin, not essential. Acts in G1 at cell cycle entry\/exit<\/td>\n<\/td>\n<\/tr>\n
rad1+<\/td>\nRAD17<\/td>\nCheckpoint factor<\/td>\nY<\/td>\n<\/tr>\n
rad2+<\/td>\nRAD27, RTH1<\/td>\nFEN1 nuclease<\/td>\nY<\/td>\n<\/tr>\n
rad3+<\/td>\nMEC1<\/td>\nATR(ATM) checkpoint kinase<\/td>\nY<\/td>\n<\/tr>\n
rad4+ cut5+<\/td>\nDPB11<\/td>\ncheckpoint and replication factor<\/td>\nY; TopBP1 or XMus101<\/td>\n<\/tr>\n
rad9+<\/td>\nDDC1<\/td>\nCheckpoint factor<\/td>\nY<\/td>\n<\/tr>\n
rad11+ rpa1+ ssb1+<\/td>\nRPA1<\/td>\nlarge subunit RPA<\/td>\nY<\/td>\n<\/tr>\n
rad13+<\/td>\nRAD2<\/td>\nexcision repair protein<\/td>\n<\/td>\n<\/tr>\n
rad15+ rhp3+ rad5+<\/td>\nRAD3<\/td>\nTFIIH subunit involved in NER and transcription<\/td>\n<\/td>\n<\/tr>\n
rad16+ rad10+ rad20+ swi9+<\/td>\nRAD1<\/td>\nNER protein<\/td>\n<\/td>\n<\/tr>\n
rad17+<\/td>\nRAD24<\/td>\ncheckpoint protein, RFC1 related<\/td>\n<\/td>\n<\/tr>\n
rad18+<\/td>\nRHC18<\/td>\nSMC-like protein involved in several repair processes<\/td>\n<\/td>\n<\/tr>\n
rad21+<\/td>\nMCD1<\/td>\ncohesin<\/td>\nY<\/td>\n<\/tr>\n
rad22+ and rti1+<\/td>\nRAD52<\/td>\nRAD52 recombination proteins<\/td>\nY<\/td>\n<\/tr>\n
rad24+<\/td>\nBMH1<\/td>\n14-3-3 protein<\/td>\nY<\/td>\n<\/tr>\n
rad25+<\/td>\nBMH2<\/td>\n14-3-3 protein<\/td>\n<\/td>\n<\/tr>\n
rad26+<\/td>\nDDC2<\/td>\ncheckpoint factor<\/td>\n<\/td>\n<\/tr>\n
rad32+<\/td>\nMRE11<\/td>\nRepair nuclease<\/td>\nY<\/td>\n<\/tr>\n
ras1+<\/td>\nRAS1 and RAS2<\/td>\nras homologue, not essential<\/td>\nY<\/td>\n<\/tr>\n
rdh54+<\/td>\nRDH54, TID1<\/td>\nmeiosis specific Rhp54 (RAD54) homologue<\/td>\nY<\/td>\n<\/tr>\n
rec8+<\/td>\nREC8<\/td>\nmeiotic cohesin, rad21+ homologue<\/td>\n<\/td>\n<\/tr>\n
rec12+<\/td>\nSPO11<\/td>\nmeiotic early-recombination protein<\/td>\n<\/td>\n<\/tr>\n
rep1+<\/td>\nno homologue?<\/td>\nmeiosis-activator of cdc10 transcription factor<\/td>\n<\/td>\n<\/tr>\n
rep2+<\/td>\nno homologue?<\/td>\nactivator of cdc10 transcription factor<\/td>\n<\/td>\n<\/tr>\n
res1+ sct1+<\/td>\nSWI4<\/td>\npartner to cdc10 transcription factor<\/td>\n<\/td>\n<\/tr>\n
res2+<\/td>\nMBP1<\/td>\npartner to cdc10 transcription factor<\/td>\n<\/td>\n<\/tr>\n
rfc1+<\/td>\nRFC1<\/td>\nReplication factor -C large subunit<\/td>\nY<\/td>\n<\/tr>\n
rfc3+<\/td>\nRFC3<\/td>\nReplication factor -C subunit 3<\/td>\nY<\/td>\n<\/tr>\n
rhp4a+ and rhp4b+<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
Incorrect nomenclature<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
Recommended is rhp41 and 42<\/td>\nRAD4<\/td>\nnucleotide-excision repair<\/td>\n<\/td>\n<\/tr>\n
rhp6+<\/td>\nRAD6 UBC2<\/td>\nrepair protein<\/td>\nY<\/td>\n<\/tr>\n
rhp9+ crb2+<\/td>\nRAD9<\/td>\nCheckpoint protein<\/td>\nY?<\/td>\n<\/tr>\n
rhp14+<\/td>\nRAD14<\/td>\nnucleotide-excision repair<\/td>\n<\/td>\n<\/tr>\n
rhp16+<\/td>\nRAD16<\/td>\nNER protein<\/td>\n<\/td>\n<\/tr>\n
rhp26+<\/td>\nRAD26<\/td>\nNER protein, SWI2\/SNF2 family<\/td>\nY<\/td>\n<\/tr>\n
rhp51+<\/td>\nRAD51<\/td>\nrecombination repair<\/td>\n<\/td>\n<\/tr>\n
rhp54+<\/td>\nRAD54<\/td>\nrecombination repair<\/td>\n<\/td>\n<\/tr>\n
rhp55+<\/td>\nRAD55<\/td>\nrecombination repair<\/td>\n<\/td>\n<\/tr>\n
rpa2+ ssb2+<\/td>\nRPA2<\/td>\nRPA subunit<\/td>\nY<\/td>\n<\/tr>\n
rpa3+ ssb3+<\/td>\nRPA3<\/td>\nRPA subunit<\/td>\n<\/td>\n<\/tr>\n
rqh1+ rad12+ hus2+<\/td>\nSGS1<\/td>\nRecQ type helicase, BLM\/WRN homologue<\/td>\nY<\/td>\n<\/tr>\n
rti1+<\/td>\nno homologue<\/td>\n2nd RAD52 homologue<\/td>\n<\/td>\n<\/tr>\n
rum1+<\/td>\nno homologue<\/td>\nCDK inhibitor; functionally similar to SIC1<\/td>\n<\/td>\n<\/tr>\n
sds1+<\/td>\nGLC7<\/td>\nPPI-class phosphatase (see dis2)<\/td>\n<\/td>\n<\/tr>\n
sfc1+<\/td>\nTFC1<\/td>\nTFCIII subunit required for polIII transcription<\/td>\n<\/td>\n<\/tr>\n
sfc3+<\/td>\nTFC3<\/td>\nTFCIII subunit required for polIII transcription<\/td>\n<\/td>\n<\/tr>\n
sfc4+<\/td>\nTFC4<\/td>\nTFCIII subunit required for polIII transcription<\/td>\n<\/td>\n<\/tr>\n
sfc6+<\/td>\nTFC6<\/td>\nTFCIII subunit required for polIII transcription<\/td>\n<\/td>\n<\/tr>\n
sid2+<\/td>\nDBF2 and DBF20<\/td>\nkinase, for septation\/cytokinesis<\/td>\n<\/td>\n<\/tr>\n
skb1+<\/td>\nHSL7<\/td>\nprotein methyltransferase<\/td>\nY<\/td>\n<\/tr>\n
skp1+ gsk3+<\/td>\nGSK3<\/td>\nglycogen synthase kinase<\/td>\nY<\/td>\n<\/tr>\n
sla1+<\/td>\nLHP1<\/td>\nLa protein binds nascent pol III transcripts<\/td>\n<\/td>\n<\/tr>\n
sld3+<\/td>\nSLD3<\/td>\nReplication factor<\/td>\n<\/td>\n<\/tr>\n
slm9+<\/td>\nHIR2<\/td>\nSynthetic lethal with cdc25<\/td>\n<\/td>\n<\/tr>\n
slp1+<\/td>\nCDC20<\/td>\nAPC activator (Fizzy)<\/td>\nY<\/td>\n<\/tr>\n
SPAC1B1.03c<\/td>\nKAP95<\/td>\nnuclear transport factor<\/td>\n<\/td>\n<\/tr>\n
SPCC1322.06<\/td>\nKAP120<\/td>\nnuclear transport factor<\/td>\n<\/td>\n<\/tr>\n
SPAC22G7.02<\/td>\nKAP122<\/td>\nnuclear transport factor<\/td>\n<\/td>\n<\/tr>\n
SPBC14F5.03C<\/td>\nKAP123<\/td>\nnuclear transport factor<\/td>\n<\/td>\n<\/tr>\n
sal3+<\/td>\nPSE1 KAP121<\/td>\nnuclear transport factor<\/td>\n<\/td>\n<\/tr>\n
SPBC30B4.05<\/td>\nCSE1<\/td>\nnuclear transport factor<\/td>\n<\/td>\n<\/tr>\n
SPCC18B5.07c<\/td>\nNUP2<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
SPAC22G7.09c<\/td>\nNUP49<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
SPBC19G7.15<\/td>\nNUP57<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
SPBC428.01c<\/td>\nNUP84<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
SPBC17G9.04c<\/td>\nNUP85<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
SPBC3B9.16c<\/td>\nNUP120<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
SPAC1805.04<\/td>\nNUP133<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
SPAC23D3.06c<\/td>\nNUP159<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
SPCC290.03c<\/td>\nNUP192<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
SPAC26A3.15c<\/td>\nNSP1<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
SPAC15F9.02<\/td>\nSEH1<\/td>\nnucleoporin<\/td>\n<\/td>\n<\/tr>\n
SPBC28F2.02<\/td>\nYOR091W<\/td>\nNuclear pore complex-associated<\/td>\n<\/td>\n<\/tr>\n
SPCC162.08<\/td>\nMLP1<\/td>\nNuclear pore complex-associated<\/td>\n<\/td>\n<\/tr>\n
SPAC2C4.11c<\/td>\nYOR145C<\/td>\nNuclear pore complex-associated<\/td>\n<\/td>\n<\/tr>\n
SPCC4B3.07<\/td>\nYOR051W<\/td>\nNuclear pore complex-associated<\/td>\n<\/td>\n<\/tr>\n
spc1+ sty1+ phh1+<\/td>\nHOG1<\/td>\nMAPK, downsream of 2 component response regulator<\/td>\n<\/td>\n<\/tr>\n
spc24+<\/td>\nSPC24<\/td>\ncentromere-associated spindle component<\/td>\n<\/td>\n<\/tr>\n
spg1+<\/td>\nTEM1<\/td>\nGTPase, involved in septation and mitotic exit<\/td>\n<\/td>\n<\/tr>\n
spk1+<\/td>\nFUS3<\/td>\nMAPK, pheromone signalling<\/td>\n<\/td>\n<\/tr>\n
SPAC3C7.06c<\/td>\nIME2 ?<\/td>\nputative protein kinase<\/td>\n<\/td>\n<\/tr>\n
srw1+ ste9+<\/td>\nHCT1\/CDH1<\/td>\nAPC activator, WD protein<\/td>\n<\/td>\n<\/tr>\n
suc1+<\/td>\nCKS1<\/td>\nsmall CDK associated protein<\/td>\nY<\/td>\n<\/tr>\n
suc22+<\/td>\nRNR2<\/td>\nsmall subunit ribonucleotide reductase<\/td>\n<\/td>\n<\/tr>\n
sud1+<\/td>\nCDC4<\/td>\nlike pop1+; SCF<\/td>\n<\/td>\n<\/tr>\n
swi1+<\/td>\nTOF1<\/td>\nrequired for mating type switching and replication fork pausing<\/td>\n<\/td>\n<\/tr>\n
swi3+<\/td>\nCSM3<\/td>\nrequired for mating type switching and replication fork pausing<\/td>\n<\/td>\n<\/tr>\n
swi4+<\/td>\nMSH3<\/td>\nMating-type switching<\/td>\n<\/td>\n<\/tr>\n
swi5+<\/td>\nSAE3<\/td>\nMating-type switching, recombination in meiosis and mitosis<\/td>\nY<\/td>\n<\/tr>\n
swi6+<\/td>\nno homologue<\/td>\nchromodomain protein, HP1 related<\/td>\nY<\/td>\n<\/tr>\n
swi10+<\/td>\nRAD10<\/td>\nNER and mating-type switching<\/td>\n<\/td>\n<\/tr>\n
taz1+<\/td>\nno homologue?<\/td>\nbinds telomeres; pombe equivalent of TRF1\/2?<\/td>\nY<\/td>\n<\/tr>\n
tea1+<\/td>\nno homologue?<\/td>\ninvolved in cell polarity<\/td>\n<\/td>\n<\/tr>\n
tea2+<\/td>\nKIP2<\/td>\nkinesin motor\/cell morphology<\/td>\n<\/td>\n<\/tr>\n
tel1+<\/td>\nTEL1<\/td>\nATM-related kinase (see rad3+)<\/td>\n<\/td>\n<\/tr>\n
trt1+<\/td>\nEST2<\/td>\ncatalytic subunit of telomerase<\/td>\n<\/td>\n<\/tr>\n
tup11+ and tup12+<\/td>\nTUP1<\/td>\nco-repressor proteins<\/td>\n<\/td>\n<\/tr>\n
uap2+<\/td>\nCUS2<\/td>\nU2 snRNP associated protein<\/td>\n<\/td>\n<\/tr>\n
ura4+<\/td>\nURA3<\/td>\norotidine 5′-phosphate decarboxylase<\/td>\n<\/td>\n<\/tr>\n
wee1+<\/td>\nSWE1<\/td>\nCDK tyrosine kinase. Not essential. Overlaps with mik1+<\/td>\nY<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n\n\n
S.cerevisiae genes without pombe homologues (decidedly incomplete)<\/th>\nGene product or protein function<\/th>\n<\/tr>\n
IME1<\/td>\nTranscription factor, required for meiosis<\/td>\n<\/tr>\n
RME1<\/td>\nZinc finger protein<\/td>\n<\/tr>\n
SPO13<\/td>\nmeiosis regulator<\/td>\n<\/tr>\n
MSH4<\/td>\nrecombination factor required in meiosis<\/td>\n<\/tr>\n
MSH5<\/td>\nrecombination factor required in meiosis<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n<\/div>\n\n\n <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":354,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-341","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nGene Conversion Table - PombeNet Forsburg Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dornsife.usc.edu\/pombenet\/gene-conversion-table\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Gene Conversion Table - PombeNet Forsburg Lab\" \/>\n<meta property=\"og:url\" content=\"https:\/\/dornsife.usc.edu\/pombenet\/gene-conversion-table\/\" \/>\n<meta property=\"og:site_name\" content=\"PombeNet Forsburg Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2023-07-13T19:34:03+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/dornsife.usc.edu\/pombenet\/gene-conversion-table\/\",\"url\":\"https:\/\/dornsife.usc.edu\/pombenet\/gene-conversion-table\/\",\"name\":\"Gene Conversion Table - 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