{"id":6464,"date":"2015-12-15T11:25:00","date_gmt":"2015-12-15T19:25:00","guid":{"rendered":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/"},"modified":"2023-04-19T11:12:26","modified_gmt":"2023-04-19T18:12:26","slug":"hunger-hormone-turns-eating-less-into-eating-more","status":"publish","type":"post","link":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/","title":{"rendered":"\u2018Hunger hormone\u2019 turns eating less into eating more"},"content":{"rendered":"\n\n\n    \n            \n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--article-hero \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--article-hero\"\n    \n      >\n\n    \n<div class=\"inner-wrapper\">\n          \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2023\/04\/story-2235-690x432.jpg\"\n                    data-sizes=\"(min-width:1200px) 75vw, (min-width:768px) 83vw, 100vw\"          class=\"lazyload\"\n        \n                  alt=\"\u2018Hunger hormone\u2019 turns eating less into eating more\"\n        \n        \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n  \n      <div class=\"image-caption\">\n          \n<div class=\"f--field f--description\">\n\n    \n  USC Dornsife&#8217;s Scott Kanoski studies the way the brain controls how and why we eat. Photo by Gus Ruelas.\n\n\n<\/div>\n    <\/div>\n  \n  <div class=\"text-wrapper\">\n          <nav aria-label=\"Breadcrumb\" class=\"breadcrumbs\">\n        <ul>\n                      <li><a href=\"\/news\/stories\/\">News<\/a><\/li>\n                      <li><a href=\"\/news\/stories\/\/?category=faculty\">Faculty<\/a><\/li>\n                  <\/ul>\n      <\/nav>\n    \n              \n<div class=\"f--field f--page-title\">\n\n    \n  <h1>\u2018Hunger hormone\u2019 turns eating less into eating more<\/h1>\n\n\n<\/div>\n    \n          <div class=\"subtitle\">\n            \n<div class=\"f--field f--description\">\n\n    \n  If scientists can suppress ghrelin\u2019s activity in the brain, they may be able to cut down on the desire to overeat, potentially offering a new countermeasure against overweight and obesity.\n\n\n<\/div>\n      <\/div>\n    \n           <strong class=\"author-field\"><span >By<\/span><a href=\"mailto:communication@dornsife.usc.edu\">Zoe Dunford<\/a><\/strong>\n    \n          <span class=\"post-date-field\">December 15, 2015<\/span>\n      <\/div>\n<\/div>\n\n\n  <\/div><\/div>\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--social-share \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--social-share\"\n    \n      >\n\n    \n  <div class=\"content-wrapper\">\n    <span class=\"a2a_kit a2a_kit_size_32 addtoany_list\" style=\"line-height: 32px;\">\n      <span class=\"title\">\n        Share\n      <\/span>\n                        <a class=\"a2a_button_copy_link\" target=\"_blank\" href=\"\/#copy_link\" rel=\"nofollow noopener\" title=\"Link\">\n            <span class=\"a2a_svg a2a_s__default a2a_s_copy_link\">\n              <svg height=\"19\" viewBox=\"0 0 19 19\" width=\"19\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"m7.43475275 9.52380952-2.17490843 2.26076008c-1.08745421 1.058837-1.68841575 2.518315-1.68841575 4.0350275 0 1.5167124.60096154 2.9475732 1.68841575 4.0350274 1.058837 1.0874543 2.51831502 1.6884158 4.03502747 1.6884158 1.44087681 0 2.80427251-.5423678 3.86936601-1.5289606l.1656615-.1594552 2.2321428-2.2321428-1.6311813-1.6311813-2.2321429 2.26076c-.6581959.658196-1.5167124 1.0016026-2.43246332 1.0016026s-1.7742674-.3434066-2.43246337-1.0016026c-.65819597-.6581959-1.00160257-1.5167124-1.00160257-2.4324633 0-.8547009.2991453-1.6595442.87416905-2.2981957l.12743352-.1342677 2.23214286-2.2321429zm6.88661855-.40736607-5.26116068 5.26116075 1.61881868 1.6188186 5.2611607-5.2611607zm1.3837569-5.54501488c-1.4408768 0-2.8042725.54236779-3.869366 1.52896062l-.1656615.15945513-2.23214282 2.23214286 1.63118132 1.63118132 2.2321429-2.23214286c.6581959-.65819597 1.5167124-1.00160256 2.4324633-1.00160256s1.7742674.34340659 2.4324634 1.00160256 1.0016026 1.51671246 1.0016026 2.43246337c0 .85470089-.2991453 1.65954419-.8741691 2.29819559l-.1274335.1342678-2.2321429 2.2321428 1.5739469 1.5739469 2.2321429-2.2321428c1.0874542-1.058837 1.6884157-2.5183151 1.6884157-4.03502751 0-1.51671245-.6009615-2.94757326-1.6884157-4.03502747-1.058837-1.08745421-2.518315-1.68841575-4.0350275-1.68841575z\" transform=\"translate(-3 -3)\"\/><\/svg>\n            <\/span>\n            <span class=\"a2a_label visually-hidden\">Copy Link<\/span>\n          <\/a>\n                                <a class=\"a2a_button_facebook\" target=\"_blank\" href=\"\/#facebook\" rel=\"nofollow noopener\" title=\"Facebook\">\n            <span class=\"a2a_svg a2a_s__default a2a_s_facebook\">\n              <svg height=\"19\" viewBox=\"0 0 19 19\" width=\"19\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"m23.9512 6h-16.9024c-.57923625 0-1.0488.46956375-1.0488 1.0488v16.9024c0 .5792362.46956375 1.0488 1.0488 1.0488h9.10024v-7.34768h-2.46772v-2.87584h2.46772v-2.11508c0-2.45404 1.49872-3.79012 3.68828-3.79012.7389668-.00263323 1.4775241.03516995 2.21236.11324v2.56348h-1.51392c-1.18788 0-1.4174.56544-1.4174 1.39612v1.8316h2.84772l-.37088 2.87584h-2.47684v7.34844h4.83284c.5792362 0 1.0488-.4695638 1.0488-1.0488v-16.9024c0-.57923625-.4695638-1.0488-1.0488-1.0488z\" fill-rule=\"evenodd\" transform=\"translate(-6 -6)\"\/><\/svg>\n            <\/span>\n            <span class=\"a2a_label visually-hidden\">Facebook<\/span>\n          <\/a>\n                                <a class=\"a2a_button_twitter\" target=\"_blank\" href=\"\/#twitter\" rel=\"nofollow noopener\" title=\"X\">\n            <span class=\"a2a_svg a2a_s__default a2a_s_twitter\">\n              <svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\"\n\t y=\"0px\" viewBox=\"0 0 30 30\" enable-background=\"new 0 0 30 30\" xml:space=\"preserve\" width=\"19\" height=\"19\">\n<path fill=\"#000\" fill-rule=\"evenodd\" clip-rule=\"evenodd\" d=\"M14.5,16.2l-0.8-1.1l-6.3-9h2.7l5.1,7.3l0.8,1.1\n\tl6.6,9.4h-2.7L14.5,16.2L14.5,16.2z M16.9,13.4l7.4-8.7h-1.8l-6.5,7.5L11,4.8H5l7.8,11.4L5,25.2h1.8l6.8-7.9l5.5,7.9h6L16.9,13.4\n\tL16.9,13.4z\"\/>\n<\/svg>\n\n            <\/span>\n            <span class=\"a2a_label visually-hidden\">X<\/span>\n          <\/a>\n                                <a class=\"a2a_button_linkedin\" target=\"_blank\" href=\"\/#linkedin\" rel=\"nofollow noopener\" title=\"Linkedin\">\n            <span class=\"a2a_svg a2a_s__default a2a_s_linkedin\">\n              <svg height=\"19\" viewBox=\"0 0 19 19\" width=\"19\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"m25 21.4220779c0 1.974026-1.6038961 3.5779221-3.5779221 3.5779221h-11.84415582c-1.97402598 0-3.57792208-1.6038961-3.57792208-3.5779221v-11.84415582c0-1.97402598 1.6038961-3.57792208 3.57792208-3.57792208h11.84415582c1.974026 0 3.5779221 1.6038961 3.5779221 3.57792208zm-14.5584416-12.21428569c-.98701295 0-1.60389606.61688311-1.60389606 1.48051949-.12337663.8636364.49350649 1.4805195 1.48051946 1.4805195.987013 0 1.6038961-.6168831 1.6038961-1.4805195 0-.86363638-.6168831-1.48051949-1.4805195-1.48051949zm1.3571429 12.70779219v-8.6363636h-2.83766234v8.6363636zm10.2402597 0v-4.9350649c0-2.5909091-1.3571428-3.8246753-3.3311688-3.8246753-1.4805195 0-2.0974026.8636363-2.4675325 1.4805194v-1.2337662h-2.8376623v8.6363636h2.8376623v-4.9350649c0-.2467532 0-.4935065.1233767-.7402597.1233766-.4935065.6168831-.987013 1.4805194-.987013.987013 0 1.4805195.7402597 1.4805195 1.974026v4.564935z\" transform=\"translate(-6 -6)\"\/><\/svg>\n            <\/span>\n            <span class=\"a2a_label visually-hidden\">LinkedIn<\/span>\n          <\/a>\n                                <a class=\"a2a_button_bluesky\" target=\"_blank\" href=\"\/#bluesky\" rel=\"nofollow noopener\" title=\"Bluesky\">\n            <span class=\"a2a_svg a2a_s__default a2a_s_bluesky\">\n              <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"50px\" height=\"50px\" viewBox=\"0 0 24 24\">\n                <path fill=\"#00000\" d=\"M12 10.8c-1.087-2.114-4.046-6.053-6.798-7.995C2.566.944 1.561 1.266.902 1.565C.139 1.908 0 3.08 0 3.768c0 .69.378 5.65.624 6.479c.815 2.736 3.713 3.66 6.383 3.364c.136-.02.275-.039.415-.056c-.138.022-.276.04-.415.056c-3.912.58-7.387 2.005-2.83 7.078c5.013 5.19 6.87-1.113 7.823-4.308c.953 3.195 2.05 9.271 7.733 4.308c4.267-4.308 1.172-6.498-2.74-7.078a8.741 8.741 0 0 1-.415-.056c.14.017.279.036.415.056c2.67.297 5.568-.628 6.383-3.364c.246-.828.624-5.79.624-6.478c0-.69-.139-1.861-.902-2.206c-.659-.298-1.664-.62-4.3 1.24C16.046 4.748 13.087 8.687 12 10.8\"  fill-rule=\"evenodd\" \/>\n              <\/svg>\n            <\/span>\n            <span class=\"a2a_label visually-hidden\">Bluesky<\/span>\n          <\/a>\n                                <a class=\"a2a_button_email\" target=\"_blank\" href=\"\/#email\" rel=\"nofollow noopener\" title=\"E-mail\">\n            <span class=\"a2a_svg a2a_s__default a2a_s_print\">\n              <svg height=\"12\" viewBox=\"0 0 18 12\" width=\"18\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"m8.14285714 9.42857143c-.17142857 0-.34285714 0-.51428571.08571428l7.28571427 6.34285719c.3428572.2571428.6857143.2571428.9428572 0l7.2857142-6.34285719c-.0857142-.08571428-.2571428-.08571428-.4285714-.08571428zm-1.28571428 1.11428567v.1714286 8.5714286c0 .6857143.6 1.2857143 1.28571428 1.2857143h14.57142856c.6857143 0 1.2857143-.6 1.2857143-1.2857143v-8.5714286c0-.0857143 0-.0857143 0-.1714286l-7.2 6.3428572c-.7714286.6857143-1.8857143.6857143-2.6571429 0z\" fill-rule=\"evenodd\" transform=\"translate(-6 -9)\"\/><\/svg>\n            <\/span>\n            <span class=\"a2a_label visually-hidden\">Email<\/span>\n          <\/a>\n                  <\/span>\n  <\/div>\n\n  <\/div><\/div>\n  \n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n      \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>Looking to avoid overeating during those big holiday meals? You might want to avoid fasting in the days beforehand. Cycles of food restriction unleash a &ldquo;hunger hormone&rdquo; that increases the capacity to eat more before getting full, according to laboratory research by USC Dornsife scientists.<\/p>\n<p>The insights, published in the journal <a href=\"http:\/\/elifesciences.org\/content\/4\/e11190\" target=\"_blank\">eLife<\/a>, could be valuable for helping the researchers develop new weight-loss therapies.<\/p>\n<p>&ldquo;We are looking deep into the higher-order functions of the brain to unpick not just which hormones are important for controlling our impulses, but also exactly how the signals and connections work,&rdquo; said lead author <a href=\"https:\/\/dornsife.usc.edu\/cf\/bisc\/faculty_display.cfm?Person_ID=1043599\">Scott Kanoski<\/a>, assistant professor of <a href=\"https:\/\/dornsife.usc.edu\/bisc\/\">biological sciences<\/a>.<\/p>\n<p><strong>A leftover from feast-or-famine days<\/strong><\/p>\n<p>Kanoski, doctoral student Ted Hsu and their colleagues conducted their studies in rats, but the work could have implications for humans. The researchers found that when they limited the time rats had access to food every day, the rats gradually were able to double their food intake to compensate.<\/p>\n<p>Over several days, the scientists allowed rats to eat only during a four-hour window, followed by 20 hours without food. The repeated short fasts sparked the hormone ghrelin to go into action prior to anticipated feeding time. That hormone reduced rats&rsquo; feeling of fullness when they were eating, so they could eat more.<\/p>\n<p>The hormone&rsquo;s action makes sense as an adaptive response: To get through times of scarcity, the brain enables the body to take in more calories during times of plenty. But that response isn&rsquo;t so relevant in the well-fed Western world anymore, Kanoski said. &ldquo;Instead, we need to find new ways to help us fight some of the feeding responses we have to external cues and circadian patterns.&rdquo;<\/p>\n<p>The USC team&rsquo;s study provides a rare look at the way ghrelin communicates with the central nervous system to control how much food is consumed.<\/p>\n<p><strong>Step away from the dinner table<\/strong><\/p>\n<p>Scientists believe that the hippocampus, a region of the brain that controls memory and motivation, is linked to the way that anticipation of food can increase food intake. In the USC study, researchers found that ghrelin communicates with neurons in the hippocampus to stimulate appetite. These neurons then communicate with another part of the brain, the hypothalamus, to produce the molecule orexin, which further promotes excessive eating. By blocking this pathway in the brain, the researchers reduced how much food the rats ate during the 4-hour feeding time.<\/p>\n<p>In previous research, Kanoski and colleagues found that ghrelin signals the hippocampus to increase rats&rsquo; food intake in response to a visual cue the rats learned to associate with an imminent meal. In the human world, that visual cue could be a fast-food billboard or vending machine that triggers a cascade of hunger signals that can be hard to resist.<\/p>\n<p>Ghrelin also has been found to increase the rate at which nutrients pass through the body. When that rate slows down, people feel fuller for longer. Understanding this system as a whole is important for finding ways to thwart it.<\/p>\n<p>The USC scientists are now experimenting with ways to reduce ghrelin&rsquo;s effects by targeting genes to suppress the activity of the ghrelin receptor in the hippocampus. This in turn disrupts the neurochemical signals that can make it easier for people to overeat.<\/p>\n<p>&ldquo;More than a third of Americans are obese and another third are <a href=\"http:\/\/www.nhlbi.nih.gov\/health\/health-topics\/topics\/obe\">overweight<\/a>,&rdquo; Kanoski said, &ldquo;so we feel we have an obligation to help identify new ways to reduce the burden on society and on our health-care system.&rdquo;<\/p>\n\n\n\n<\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>If scientists can suppress ghrelin\u2019s activity in the brain, they may be able to cut down on the desire to overeat, potentially offering a new countermeasure against overweight and obesity.<\/p>\n","protected":false},"author":0,"featured_media":6467,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[10,17],"tags":[117,96,632,481],"class_list":["post-6464","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-faculty","category-student","tag-biology","tag-natural-sciences","tag-obesity","tag-scott-kanoski"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u2018Hunger hormone\u2019 turns eating less into eating more<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u2018Hunger hormone\u2019 turns eating less into eating more\" \/>\n<meta property=\"og:description\" content=\"If scientists can suppress ghrelin\u2019s activity in the brain, they may be able to cut down on the desire to overeat, potentially offering a new countermeasure against overweight and obesity.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/\" \/>\n<meta property=\"og:site_name\" content=\"USC Dornsife News\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/uscdornsife\" \/>\n<meta property=\"article:published_time\" content=\"2015-12-15T19:25:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-04-19T18:12:26+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/dornsife.usc.edu\/wp-content\/uploads\/sites\/7\/2023\/04\/story-2235.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"690\" \/>\n\t<meta property=\"og:image:height\" content=\"450\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@uscdornsife\" \/>\n<meta name=\"twitter:site\" content=\"@uscdornsife\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/\"},\"author\":{\"name\":\"\",\"@id\":\"\"},\"headline\":\"\u2018Hunger hormone\u2019 turns eating less into eating more\",\"datePublished\":\"2015-12-15T19:25:00+00:00\",\"dateModified\":\"2023-04-19T18:12:26+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/\"},\"wordCount\":8,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/dornsife.usc.edu\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2023\/04\/story-2235.jpg\",\"keywords\":[\"biology\",\"natural sciences\",\"obesity\",\"scott kanoski\"],\"articleSection\":[\"Faculty\",\"Student\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/\",\"url\":\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/\",\"name\":\"\u2018Hunger hormone\u2019 turns eating less into eating more\",\"isPartOf\":{\"@id\":\"https:\/\/dornsife.usc.edu\/news\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2023\/04\/story-2235.jpg\",\"datePublished\":\"2015-12-15T19:25:00+00:00\",\"dateModified\":\"2023-04-19T18:12:26+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#primaryimage\",\"url\":\"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2023\/04\/story-2235.jpg\",\"contentUrl\":\"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2023\/04\/story-2235.jpg\",\"width\":690,\"height\":450,\"caption\":\"\u2018Hunger hormone\u2019 turns eating less into eating more\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/dornsife.usc.edu\/news\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u2018Hunger hormone\u2019 turns eating less into eating more\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/dornsife.usc.edu\/news\/#website\",\"url\":\"https:\/\/dornsife.usc.edu\/news\/\",\"name\":\"USC Dornsife News\",\"description\":\"USC Dornsife news and events\",\"publisher\":{\"@id\":\"https:\/\/dornsife.usc.edu\/news\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/dornsife.usc.edu\/news\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/dornsife.usc.edu\/news\/#organization\",\"name\":\"USC Dornsife News\",\"url\":\"https:\/\/dornsife.usc.edu\/news\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/dornsife.usc.edu\/news\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2024\/01\/USC-Dornsife-Cardinal-Black-on-White-RGB.jpg\",\"contentUrl\":\"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2024\/01\/USC-Dornsife-Cardinal-Black-on-White-RGB.jpg\",\"width\":1000,\"height\":330,\"caption\":\"USC Dornsife News\"},\"image\":{\"@id\":\"https:\/\/dornsife.usc.edu\/news\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/uscdornsife\",\"https:\/\/x.com\/uscdornsife\",\"https:\/\/www.instagram.com\/uscdornsife\/\",\"https:\/\/www.youtube.com\/user\/USCCollege\",\"https:\/\/www.linkedin.com\/school\/uscdornsife\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u2018Hunger hormone\u2019 turns eating less into eating more","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/","og_locale":"en_US","og_type":"article","og_title":"\u2018Hunger hormone\u2019 turns eating less into eating more","og_description":"If scientists can suppress ghrelin\u2019s activity in the brain, they may be able to cut down on the desire to overeat, potentially offering a new countermeasure against overweight and obesity.","og_url":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/","og_site_name":"USC Dornsife News","article_publisher":"https:\/\/www.facebook.com\/uscdornsife","article_published_time":"2015-12-15T19:25:00+00:00","article_modified_time":"2023-04-19T18:12:26+00:00","og_image":[{"width":690,"height":450,"url":"https:\/\/dornsife.usc.edu\/wp-content\/uploads\/sites\/7\/2023\/04\/story-2235.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_creator":"@uscdornsife","twitter_site":"@uscdornsife","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#article","isPartOf":{"@id":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/"},"author":{"name":"","@id":""},"headline":"\u2018Hunger hormone\u2019 turns eating less into eating more","datePublished":"2015-12-15T19:25:00+00:00","dateModified":"2023-04-19T18:12:26+00:00","mainEntityOfPage":{"@id":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/"},"wordCount":8,"commentCount":0,"publisher":{"@id":"https:\/\/dornsife.usc.edu\/news\/#organization"},"image":{"@id":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#primaryimage"},"thumbnailUrl":"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2023\/04\/story-2235.jpg","keywords":["biology","natural sciences","obesity","scott kanoski"],"articleSection":["Faculty","Student"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/","url":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/","name":"\u2018Hunger hormone\u2019 turns eating less into eating more","isPartOf":{"@id":"https:\/\/dornsife.usc.edu\/news\/#website"},"primaryImageOfPage":{"@id":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#primaryimage"},"image":{"@id":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#primaryimage"},"thumbnailUrl":"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2023\/04\/story-2235.jpg","datePublished":"2015-12-15T19:25:00+00:00","dateModified":"2023-04-19T18:12:26+00:00","breadcrumb":{"@id":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#primaryimage","url":"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2023\/04\/story-2235.jpg","contentUrl":"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2023\/04\/story-2235.jpg","width":690,"height":450,"caption":"\u2018Hunger hormone\u2019 turns eating less into eating more"},{"@type":"BreadcrumbList","@id":"https:\/\/dornsife.usc.edu\/news\/stories\/hunger-hormone-turns-eating-less-into-eating-more\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/dornsife.usc.edu\/news\/"},{"@type":"ListItem","position":2,"name":"\u2018Hunger hormone\u2019 turns eating less into eating more"}]},{"@type":"WebSite","@id":"https:\/\/dornsife.usc.edu\/news\/#website","url":"https:\/\/dornsife.usc.edu\/news\/","name":"USC Dornsife News","description":"USC Dornsife news and events","publisher":{"@id":"https:\/\/dornsife.usc.edu\/news\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/dornsife.usc.edu\/news\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/dornsife.usc.edu\/news\/#organization","name":"USC Dornsife News","url":"https:\/\/dornsife.usc.edu\/news\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/dornsife.usc.edu\/news\/#\/schema\/logo\/image\/","url":"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2024\/01\/USC-Dornsife-Cardinal-Black-on-White-RGB.jpg","contentUrl":"https:\/\/dornsife.usc.edu\/news\/wp-content\/uploads\/sites\/7\/2024\/01\/USC-Dornsife-Cardinal-Black-on-White-RGB.jpg","width":1000,"height":330,"caption":"USC Dornsife News"},"image":{"@id":"https:\/\/dornsife.usc.edu\/news\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/uscdornsife","https:\/\/x.com\/uscdornsife","https:\/\/www.instagram.com\/uscdornsife\/","https:\/\/www.youtube.com\/user\/USCCollege","https:\/\/www.linkedin.com\/school\/uscdornsife"]}]}},"_links":{"self":[{"href":"https:\/\/dornsife.usc.edu\/news\/wp-json\/wp\/v2\/posts\/6464","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dornsife.usc.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dornsife.usc.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/dornsife.usc.edu\/news\/wp-json\/wp\/v2\/comments?post=6464"}],"version-history":[{"count":2,"href":"https:\/\/dornsife.usc.edu\/news\/wp-json\/wp\/v2\/posts\/6464\/revisions"}],"predecessor-version":[{"id":6466,"href":"https:\/\/dornsife.usc.edu\/news\/wp-json\/wp\/v2\/posts\/6464\/revisions\/6466"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dornsife.usc.edu\/news\/wp-json\/wp\/v2\/media\/6467"}],"wp:attachment":[{"href":"https:\/\/dornsife.usc.edu\/news\/wp-json\/wp\/v2\/media?parent=6464"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dornsife.usc.edu\/news\/wp-json\/wp\/v2\/categories?post=6464"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dornsife.usc.edu\/news\/wp-json\/wp\/v2\/tags?post=6464"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}