{"id":205,"date":"2025-04-07T17:31:40","date_gmt":"2025-04-08T00:31:40","guid":{"rendered":"https:\/\/dornsife.usc.edu\/grayson-jaggers-phd\/?page_id=205"},"modified":"2025-04-07T17:35:33","modified_gmt":"2025-04-08T00:35:33","slug":"bisc-438","status":"publish","type":"page","link":"https:\/\/dornsife.usc.edu\/grayson-jaggers-phd\/bisc-438\/","title":{"rendered":"BISC 438 Nutritional Biochemistry (4 Units)"},"content":{"rendered":"\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n      \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <h2 style=\"text-align: center;\"><strong>2023 Fall Semester<\/strong><\/h2>\n<h2 style=\"text-align: center;\"><strong> Syllabus<\/strong><\/h2>\n<p><strong>Day\/Time: <\/strong>Monday, Wednesday, and Friday 2:00 &#8211; 2:50 PM<br \/>\n<strong>Location: <\/strong>VHE 206<\/p>\n<p><strong>Instructor: <\/strong>Grayson Jaggers, PhD<br \/>\n<strong>Office: <\/strong>ZHS 256<br \/>\n<strong>Office Hours: <\/strong>Wednesdays 12:45-1:45PM, Tuesday 4:00-4:50PM<br \/>\n<strong>Email: <\/strong><a href=\"mailto:jaggers@usc.edu\">jaggers@usc.edu<\/a> (Please allow 24 hours for a response)<\/p>\n<p>&nbsp;<\/p>\n<h2>Course Description<\/h2>\n<p>We all understand that the carbohydrates, proteins, and fats we consume provide our bodies with energy, but there are biologically-active nutritional chemicals that do not provide energy. What roles do these molecules serve in our body? By what mechanisms do they impact our health? These are the questions that we will address throughout this course.<\/p>\n<p>The class will consist of a mixture of lecture and in-class discussion. Topics covered include, amino acid metabolism, lipid synthesis, and the metabolic functions of vitamins and minerals. The course will also explore the functions of biologically-active non- nutrients such as caffeine and phytochemicals. This course will reinforce the principles taught in BISC 330\/312, and expand upon them as students learn the biochemical basis of nutrition\u2019s impact on metabolic functions.<\/p>\n<p>&nbsp;<\/p>\n<h2>Learning Objectives<\/h2>\n<p>After completion of homework, in-class discussions and examinations, students should be able to effectively execute the following:<\/p>\n<ol>\n<li>Clear written communication of complex concepts in<\/li>\n<li>Compare and contrast biochemical regulatory<\/li>\n<li>Establish connections between the metabolism of various<\/li>\n<li>Establish connections between nutrient metabolism and nutrition-based<\/li>\n<\/ol>\n<p><strong>Prerequisite: <\/strong>BISC 330 (Biochemistry), BISC 312 (Molecular Biochemistry)<\/p>\n<h2>I.\u00a0 Textbook (Optional)<\/h2>\n<p>Stipanuck, Martha H., Caudill, Marie A. Biochemical, Physiological, and Molecular Aspects of Human Nutrition (4th Edition, 2019).<\/p>\n<h2>II.\u00a0 Description and Assessment of Assignments<\/h2>\n<p>Exams are typically 30% multiple-choice, and 70% written response. They will be based upon concepts discussed in lecture and homework. Any information presented outside of lecture or homework assignments will not be tested upon, unless specifically stated.<\/p>\n<p>Homework contains problems that require a written response. Homework that receives full credit will be turned in before the beginning of class, and contains well-reasoned and accurate responses to the questions. Late homework will not be accepted. Exceptions can be made for students under certain circumstances.<\/p>\n<h2>III.\u00a0 Grading Breakdown<\/h2>\n<p>The course grade will be based upon four lecture exams and homework. Each exam will be worth 100 points (21.7% of the overall grade). There are six homework assignments worth 10 points each (totaling 13% of the overall grade).<\/p>\n<p>Midterm 1: 100 points\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Midterm 2: 100 points<\/p>\n<p>Midterm 3: 100 points\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Final Exam: 100 points<\/p>\n<p>Homework: 60 points<\/p>\n<p><strong>Total: 460 points<\/strong><\/p>\n<p><em><u>Typical<\/u><\/em> <em>Grade Breakdown <\/em>(Just to give you an idea, but not guaranteed)<em>:<\/em><\/p>\n<p>A range: 85-100%\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 B range: 70-84%\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 C range: 60-69%<\/p>\n<p><strong><em>Attendance: <\/em><\/strong>Exams must be taken during the scheduled class period. Attendance in lecture is not required, but is recommended, as we will be reviewing homework as well as going over lecture material.<\/p>\n<h2>IV.\u00a0 Tentative Lecture and Exam Schedule<\/h2>\n<table>\n<tbody>\n<tr>\n<td width=\"49\"><strong>Week<\/strong><\/td>\n<td width=\"74\"><strong>Date<\/strong><\/td>\n<td width=\"458\"><strong>Topic<\/strong><\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">1<\/td>\n<td width=\"74\">21-Aug<\/td>\n<td width=\"458\">Intro to Nutritional Biochemistry, Review of Glycolysis and \u03b2-oxidation<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">23-Aug<\/td>\n<td width=\"458\">Digestion and Absorption<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">25-Aug<\/td>\n<td width=\"458\">Digestion and Absorption of Carbohydrates and Protein<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">2<\/td>\n<td width=\"74\">28-Aug<\/td>\n<td width=\"458\">Lipid Digestion and Absorption<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">30-Aug<\/td>\n<td width=\"458\">Amino Acid Metabolism I<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">1-Sep<\/td>\n<td width=\"458\">Amino Acid Metabolism II<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">3<\/td>\n<td width=\"74\">4-Sep<\/td>\n<td width=\"458\"><strong>Labor Day<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"74\">6-Sep<\/td>\n<td width=\"458\">Lipid Metabolism<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">8-Sep<\/td>\n<td width=\"458\">Cholesterol Synthesis and Metabolism<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">4<\/td>\n<td width=\"74\">11-Sep<\/td>\n<td width=\"458\"><strong>Homework<\/strong> <strong>Discussion<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"74\">13-Sep<\/td>\n<td width=\"458\"><strong>Midterm 1<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"74\">15-Sep<\/td>\n<td width=\"458\">Fuel Regulation and Energy Balance<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">5<\/td>\n<td width=\"74\">18-Sep<\/td>\n<td width=\"458\">Water-Soluble Vitamins &#8211; Niacin<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">20-Sep<\/td>\n<td width=\"458\">Water-Soluble Vitamins &#8211; Riboflavin &amp; Thiamin<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">22-Sep<\/td>\n<td width=\"458\">Water-Soluble Vitamins &#8211; Folate<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">6<\/td>\n<td width=\"74\">25-Sep<\/td>\n<td width=\"458\">Water-Soluble Vitamins &#8211; Choline<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">27-Sep<\/td>\n<td width=\"458\">Water-Soluble Vitamins &#8211; Vitamin C<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">29-Sep<\/td>\n<td width=\"458\">Fat-Soluble Vitamins &#8211; Vitamin E<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">7<\/td>\n<td width=\"74\">2-Oct<\/td>\n<td width=\"458\">Fat-Soluble Vitamins &#8211; Vitamin K<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">4-Oct<\/td>\n<td width=\"458\"><strong>Homework<\/strong> <strong>Discussion<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"74\">6-Oct<\/td>\n<td width=\"458\"><strong>Midterm 2<\/strong><\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">8<\/td>\n<td width=\"74\">9-Oct<\/td>\n<td width=\"458\">Fat-Soluble Vitamins &#8211; Vitamin A<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">11-Oct<\/td>\n<td width=\"458\">Fat-Soluble Vitamins &#8211; Vitamin D<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">13-Oct<\/td>\n<td width=\"458\"><strong>Fall Recess<\/strong><\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">9<\/td>\n<td width=\"74\">16-Oct<\/td>\n<td width=\"458\">Mineral Metabolism \u2013 Calcium<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">18-Oct<\/td>\n<td width=\"458\">Mineral Metabolism &#8211; Iron<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">20-Oct<\/td>\n<td width=\"458\"><strong>Homework<\/strong> <strong>Discussion<\/strong><\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">10<\/td>\n<td width=\"74\">23-Oct<\/td>\n<td width=\"458\">Mineral Metabolism &#8211; Iodine<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">25-Oct<\/td>\n<td width=\"458\">Water Balance<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">27-Oct<\/td>\n<td width=\"458\">Alkaloids<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">11<\/td>\n<td width=\"74\">30-Oct<\/td>\n<td width=\"458\">Alkaloids<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">1-Nov<\/td>\n<td width=\"458\"><strong>Homework<\/strong> <strong>Discussion<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"74\">3-Nov<\/td>\n<td width=\"458\"><strong>Midterm 3<\/strong><\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">12<\/td>\n<td width=\"74\">6-Nov<\/td>\n<td width=\"458\">Alcohol Metabolism<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">8-Nov<\/td>\n<td width=\"458\">Alcohol Metabolism<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">10-Nov<\/td>\n<td width=\"458\">Polyunsaturated Fatty Acids<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">13<\/td>\n<td width=\"74\">13-Nov<\/td>\n<td width=\"458\">Polyphenols<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">15-Nov<\/td>\n<td width=\"458\">Polyphenols<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">17-Nov<\/td>\n<td width=\"458\"><strong>Homework<\/strong> <strong>Discussion<\/strong><\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">14<\/td>\n<td width=\"74\">20-Nov<\/td>\n<td width=\"458\">Polyphenols<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">22-Nov<\/td>\n<td width=\"458\"><strong>Thanksgiving<\/strong> <strong>Break<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"74\">24-Nov<\/td>\n<td width=\"458\"><strong>Thanksgiving<\/strong> <strong>Break<\/strong><\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" width=\"49\">15<\/td>\n<td width=\"74\">27-Nov<\/td>\n<td width=\"458\">Phytosterols<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">29-Nov<\/td>\n<td width=\"458\">Phytoestrogens<\/td>\n<\/tr>\n<tr>\n<td width=\"74\">1-Dec<\/td>\n<td width=\"458\"><strong>Homework<\/strong> <strong>Discussion<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Final Exam: <\/strong>Friday, December 8th, 2-4PM<\/p>\n<p>&nbsp;<\/p>\n<h2>VI. Statement on Academic Conduct and Support Systems<\/h2>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong>Academic Conduct:<\/strong><\/p>\n<p>Plagiarism \u2013 presenting someone else\u2019s ideas as your own, either verbatim or recast in your own words \u2013 is a serious academic offense with serious consequences. Please familiarize yourself with the discussion of plagiarism in <em>SCampus <\/em>in Part B, Section 11, \u201cBehavior Violating University Standards\u201d <a href=\"https:\/\/policy.usc.edu\/scampus-part-b\">policy.usc.edu\/scampus-part-b<\/a>. Other forms of academic dishonesty are equally unacceptable. See additional information<\/p>\n<p>in <em>SCampus <\/em>and university policies on scientific misconduct, <a href=\"http:\/\/policy.usc.edu\/scientific-misconduct\">http:\/\/policy.usc.edu\/scientific-misconduct<\/a>.<\/p>\n<p><strong>Support Systems:<\/strong><\/p>\n<p><em>Student Counseling Services (SCS) \u2013 (213) 740-7711 \u2013 24\/7 on call<\/em><\/p>\n<p>Free and confidential mental health treatment for students, including short-term psychotherapy, group counseling, stress fitness workshops, and crisis intervention. <a href=\"https:\/\/engemannshc.usc.edu\/counseling\">engemannshc.usc.edu\/counseling<\/a><\/p>\n<p><strong><em>National Suicide Prevention Lifeline <\/em><\/strong><em>\u2013 1 (800) 273-8255<\/em><\/p>\n<p>Provides free and confidential emotional support to people in suicidal crisis or emotional distress 24 hours a day, 7 days a week. <a href=\"https:\/\/www.suicidepreventionlifeline.org\/\">www.suicidepreventionlifeline.org<\/a><\/p>\n<p><strong><em>Relationship and Sexual Violence Prevention Services <\/em><\/strong><em>(RSVP) \u2013 (213) 740-4900 \u2013 24\/7 on call<\/em><\/p>\n<p>Free and confidential therapy services, workshops, and training for situations related to gender-based harm. <a href=\"https:\/\/engemannshc.usc.edu\/rsvp\">engemannshc.usc.edu\/rsvp<\/a><\/p>\n<p><strong>Sexual Assault Resource Center<\/strong><\/p>\n<p>For more information about how to get help or help a survivor, rights, reporting options, and additional resources, visit the website: <a href=\"https:\/\/sarc.usc.edu\/\">sarc.usc.edu<\/a><\/p>\n<p><strong><em>Office of Equity and Diversity (OED)\/Title IX Compliance <\/em><\/strong><em>\u2013 (213) 740-5086<\/em><\/p>\n<p>Works with faculty, staff, visitors, applicants, and students around issues of protected class. <a href=\"https:\/\/equity.usc.edu\/\">equity.usc.edu<\/a><\/p>\n<p><strong>Bias Assessment Response and Support<\/strong><\/p>\n<p>Incidents of bias, hate crimes and microaggressions need to be reported allowing for appropriate investigation and response. <a href=\"https:\/\/studentaffairs.usc.edu\/bias-assessment\">studentaffairs.usc.edu\/bias-assessment<\/a><u>&#8211;<\/u> <u>response-support<\/u><\/p>\n<p><strong>The Office of Disability Services and Programs<\/strong><\/p>\n<p>Provides certification for students with disabilities and helps arrange relevant accommodations. <a href=\"https:\/\/dsp.usc.edu\/\">dsp.usc.edu<\/a><\/p>\n<p><strong><em>Student Support and Advocacy <\/em><\/strong><em>\u2013 (213) 821-4710<\/em><\/p>\n<p>Assists students and families in resolving complex issues adversely affecting their success as a student EX: personal, financial, and academic. <a href=\"https:\/\/studentaffairs.usc.edu\/ssa\">studentaffairs.usc.edu\/ssa<\/a><\/p>\n<p><strong>Diversity at USC<\/strong><\/p>\n<p>Information on events, programs and training, the Diversity Task Force (including representatives for each school), chronology, participation, and various resources for students. <a href=\"https:\/\/diversity.usc.edu\/\">diversity.usc.edu<\/a><\/p>\n<p><strong>USC Emergency Information<\/strong><\/p>\n<p>Provides safety and other updates, including ways in which instruction will be continued if an officially declared emergency makes travel to campus infeasible. <a href=\"https:\/\/emergency.usc.edu\/\">emergency.usc.edu<\/a><\/p>\n<p><strong><em>USC Department of Public Safety <\/em><\/strong><em>\u2013 UPC: (213) 740-4321 \u2013 HSC: (323) 442-1000 \u2013 24- hour emergency or to report a crime.<\/em><\/p>\n<p>Provides overall safety to USC community. <a href=\"https:\/\/dps.usc.edu\/\">dps.usc.edu<\/a><\/p>\n<p><strong>End-of-Semester Evaluations<\/strong><\/p>\n<p>I value your thoughts on the course, and myself, as your instructor. At the end of the semester, please take time to complete the course and instructor evaluations. I am always trying to improve the course, and this is a great way for me to utilize your insight.<\/p>\n\n\n\n<\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-205","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>BISC 438 Nutritional Biochemistry (4 Units) - Grayson Jaggers, PhD<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dornsife.usc.edu\/grayson-jaggers-phd\/bisc-438\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BISC 438 Nutritional Biochemistry (4 Units) - 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