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Providing Continuity in Infant Mental Health Services for Medically Fragile Infants and Their Families

"Having a baby who is prenatally or postnatally diagnosed with a medical condition places considerable stress on the parents, infants, and their developing relationship. Infant mental health (IMH) services offer an opportunity to address the challenges and support the parent-infant relationship. The present study outlined a continuum of care IMH program embedded within various medical settings of a large metropolitan children’s hospital. Applications of IMH principles within the fetal care center, neonatal intensive care unit, high risk infant follow-up clinic, and the patient’s home are described. Descriptive data about families served across settings and a case study are provided in order to illustrate the implementation of this unique IMH intervention model. " Read More

Pediatric subspecialty healthcare providers’ views of recruitment during a randomized controlled trial of a mobile health intervention

Randomized clinical trials (RCTs) enrolling pediatric populations often struggle with recruitment. Engaging healthcare providers in the recruitment process may increase patients' and caregivers' willingness to participate in research. The purpose of this study was to understand the perspectives of pediatric subspecialty healthcare providers considering recruiting patients to participate in an mobile health (mHealth) RCT. Read More

Longitudinal profiles of the fecal metabolome during the first 2 years of life

During the first 2 years of life, the infant gut microbiome is rapidly developing, and gut bacteria may impact host health through the production of metabolites that can have systemic effects. Thus, the fecal metabolome represents a functional readout of gut bacteria. Despite the important role that fecal metabolites may play in infant health, the development of the infant fecal metabolome has not yet been thoroughly characterized using frequent, repeated sampling during the first 2 years of life. Read More

Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders

In this review, we summarize findings from imaging genetics studies spanning from early infancy to early childhood, with a focus on studies examining genetic risk for neuropsychiatric disorders. We also introduce the Organization for Imaging Genomics in Infancy (ORIGINs), a working group of the ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) consortium, which was established to facilitate large-scale imaging genetics studies in infancy and early childhood. Read More

The Influences of Children’s and Maternal Childhood Adversity on Externalizing Problems in Early Adolescence

Childhood adversities have been linked to externalizing problems in adolescence. However, studies focusing on early adolescence are rare. Even less empirical attention has been given to the unique and joint influences of children’s and maternal childhood adversity on children’s externalizing behavior, particularly with a keen focus on the nature of adversities. This study examined the influences of children’s and maternal childhood adversities on children’s externalizing problems in early adolescence, delineating domains of childhood adversities. Read More