{"id":272,"date":"2023-09-18T12:27:22","date_gmt":"2023-09-18T19:27:22","guid":{"rendered":"https:\/\/dornsife.usc.edu\/bottjerlab\/?page_id=272"},"modified":"2023-10-11T12:53:07","modified_gmt":"2023-10-11T19:53:07","slug":"alex-chung","status":"publish","type":"page","link":"https:\/\/dornsife.usc.edu\/bottjerlab\/alex-chung\/","title":{"rendered":"Alex Chung"},"content":{"rendered":"\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n      \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>As described on Sarah&#8217;s page, parallel cortico-basal ganglia circuits offer a neural architecture that can process related but distinct types of information.\u00a0 In our working model the core circuits drive vocal motor output and hence are a &#8220;performance&#8221; pathway, while the shell circuits are a &#8220;comparator&#8221; pathway that evaluates similarity of self-generated babbling sounds to tutor goal sounds.\u00a0 We think it is likely that as the shell circuits perform evaluation of what utterances constitute a good match to the goal, they somehow instruct the core circuits to refine their motor output.\u00a0 But that means there must be points of information exchange between shell and core pathways.\u00a0 I am investigating possible ways in which the information processed in shell and core pathways is integrated.\u00a0 The specific hypothesis I am currently investigating is whether both RA (core pathway) and AId (shell pathway) converge in the thalamus in juvenile birds during skill learning.\u00a0 That would bring together information from core and shell pathways through the cortex, as well as converge with basal ganglia outflow to thalamus.<\/p>\n<table border=\"0\" cellspacing=\"4\">\n<tbody>\n<tr>\n<td><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/dornsife.usc.edu\/bottjerlab\/wp-content\/uploads\/sites\/239\/2023\/10\/DLM_20x_mag_injection_in_RA_and_LMAN.jpg\" width=\"300\" height=\"300\" \/><\/td>\n<td><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/dornsife.usc.edu\/bottjerlab\/wp-content\/uploads\/sites\/239\/2023\/10\/coreshell_for_Lauren_proposal.jpg\" width=\"360\" height=\"260\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>The confocal image on the left depicts the thalamic nucleus DLM following tracer injections into RA and LMAN-core.\u00a0 The red cells project to LMAN-core, and the green axons from RA are clearly intermingled, indicating that RA axons make a connection with thalamic cells that project back to LMAN-core in juveniles.\u00a0 In the schematic on the right, gray represents core regions and red represents shell regions.<\/p>\n<p>&nbsp;<\/p>\n<p>In my free time I am an avid rock climber.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/dornsife.usc.edu\/bottjerlab\/wp-content\/uploads\/sites\/239\/2023\/10\/Alex2.jpg\" width=\"400\" height=\"423\" \/><\/p>\n\n\n\n<\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":659,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-272","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - 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