VP-ITC Isothermal Titration Calorimeter

The VP-ITC system is an ultrasensitive isothermal titration calorimeter designed for ease-of-use.  All functions are operated through software to minimize operator involvement and facilitate fast and accurate analyses without the need for expertise in thermodynamics.

Applications:

• Characterization of molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules.
• Lead optimization.
• Enzyme kinetics.
• Assessment of the effect of molecular structure changes on binding mechanisms.
• Assessment of biological activity.

VP-ITC features:

• Active cell volume ~ 1.4 ml.
• Non-reactive Hastelloy® cells for excellent chemical resistance.
• Fixed-in-place cells for reproducible ultrasensitive performance with low maintenance.
• Precision liquid delivery system for accurate and reproducible injections.
• User-selectable mixing speeds to match sample conditions.
• Three user selectable response times for application versatility.  
• Operating temperature range of 2ºC to 80ºC.
• Peltier controlled for rapid temperature equilibration.
• Includes ThermoVac® sample preparation and cleaning device.

Contact information:

        Please contact ITC specialist Alan Situ(asitu@usc.edu) in Dr. Tobias Ulmer lab for more information.