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Ian Ehrenreich

Assistant Professor of Biological Sciences

Contact Information
E-mail: Ian.Ehrenreich@usc.edu
Phone: (213) 821-5349
Office: RRI 319A



Ph.D. Genetics, North Carolina State University, 2008
B.A. Human Biology, Stanford University, 2002

Postdoctoral Training

NIH NRSA Postdoctoral Fellow, Princeton University, 2008-2011  

Description of Research

Summary Statement of Research Interests

We study two main problems. First, we are focused on improving general understanding of how DNA specifies the characteristics of organisms. Much of this work involves using variation among individuals within species or differences between closely related species to systematically probe how multiple genes independently and in combination exert their effects on complex traits. We also use classical genetic approaches based on random and targeted mutagenesis to identify the genes and pathways that encode phenotypes that are likely to be important to the natural ecology of organisms. Second, we are generally interested in using large-scale whole genome sequencing to understand the selection pressures populations experience in nature. Our hope is that by examining populations over time, we will be able to directly observe the effects of natural selection on the genome and from this we will be able to identify the functional mechanisms by which populations adapt to dynamic environmental conditions.

Research Keywords

quantitative genetics, genomics, genetics, population genomics, next generation sequencing, adaptation, ecological genomics, microbiology, microorganisms


Journal Article

Jang, H., Ehrenreich, I. M. (2012). Genome-Wide Characterization of Genetic Variation in the Unicellular, Green Alga Chlamydomonas reinhardtii. PLoS ONE. Vol. 7 (7), pp. e41307.
Banta, J. A., Ehrenreich, I. M., Gerard, S., Chou, L., Wilczek, A., Schmitt, J., Kover, P. X., Purugganan, M. D. (2012). Climate envelope modelling reveals intraspecific relationships among flowering phenology, niche breadth and potential range size in Arabidopsis thaliana. Ecology Letters. Vol. 15 (8), pp. 769-777.
Ehrenreich, I. M., Bloom, J., Torabi, N., Wang, X., Jia, Y., Kruglyak, L. (2012). Genetic Architecture of Highly Complex Chemical Resistance Traits across Four Yeast Strains. PLoS Genetics. Vol. 8 (3), pp. e1002570.
Ehrenreich, I. M., Torabi, N., Jia, Y., Kent, J., Martis, S., Shapiro, J. A., Gresham, D., Caudy, A. A., Kruglyak, L. (2010). Dissection of genetically complex traits with extremely large pools of yeast segregants. Nature. Vol. 464 (72912010/04/16), pp. 1039-42.
Caicedo, A. L., Richards, C., Ehrenreich, I. M., Purugganan, M. D. (2009). Complex rearrangements lead to novel chimeric gene fusion polymorphisms at the Arabidopsis thaliana MAF2-5 flowering time gene cluster. Mol Biol Evol. Vol. 26 (32009/01/14), pp. 699-711.
Ehrenreich, I. M., Gerke, J. P., Kruglyak, L. (2009). Genetic dissection of complex traits in yeast: insights from studies of gene expression and other phenotypes in the BYxRM cross. Cold Spring Harb Symp Quant Biol. Vol. 74 (2009/09/08), pp. 145-53.
Ehrenreich, I. M., Hanzawa, Y., Chou, L., Roe, J. L., Kover, P. X., Purugganan, M. D. (2009). Candidate gene association mapping of Arabidopsis flowering time. Genetics. Vol. 183 (12009/07/08), pp. 325-35.
Kover, P. X., Valdar, W., Trakalo, J., Scarcelli, N., Ehrenreich, I. M., Purugganan, M. D., Durrant, C., Mott, R. (2009). A Multiparent Advanced Generation Inter-Cross to fine-map quantitative traits in Arabidopsis thaliana. PLoS Genet. Vol. 5 (72009/07/14), pp. e1000551.
Webb, E. A., Ehrenreich, I. M., Brown, S. L., Valois, F. W., Waterbury, J. B. (2009). Phenotypic and genotypic characterization of multiple strains of the diazotrophic cyanobacterium, Crocosphaera watsonii, isolated from the open ocean. Environ Microbiol. Vol. 11 (22009/02/07), pp. 338-48.
Ehrenreich, I. M., Purugganan, M. (2008). MicroRNAs in plants: Possible contributions to phenotypic diversity. Plant Signal Behav. Vol. 3 (102009/08/26), pp. 829-30.
Ehrenreich, I. M., Purugganan, M. D. (2008). Sequence variation of MicroRNAs and their binding sites in Arabidopsis. Plant Physiol. Vol. 146 (42008/02/29), pp. 1974-82.
Ehrenreich, I. M., Stafford, P. A., Purugganan, M. D. (2007). The genetic architecture of shoot branching in Arabidopsis thaliana: a comparative assessment of candidate gene associations vs. quantitative trait locus mapping. Genetics. Vol. 176 (22007/04/17), pp. 1223-36.
Ehrenreich, I. M., Purugganan, M. D. (2006). The molecular genetic basis of plant adaptation. American Journal of Botany. Vol. 93 (7), pp. 953-962.
Ehrenreich, I. M., Waterbury, J. B., Webb, E. A. (2005). Distribution and diversity of natural product genes in marine and freshwater cyanobacterial cultures and genomes. Appl Environ Microbiol. Vol. 71 (112005/11/05), pp. 7401-13.
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