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Xuelin Wu

Assistant Professor (Research) of Biological Sciences

Contact Information
E-mail: xuelinwu@usc.edu
Phone: (213) 740-2165
Office: RRI 304B

 

Education

Ph.D. Developmental Biology, New York University, New York, 2/2000
B.S. Molecular Biology, University of Science and Technology of China, China, 7/1993
 

Postdoctoral Training

Postdoctoral Research Associate, The Salk Institute for Biological Studies, 05/15/2000-12/30/2006  
 

Academic Appointment, Affiliation, and Employment History

Assistant Professor, University of Southern California, 01/01/2007-  
 

Description of Research

Summary Statement of Research Interests

The research in my lab is aimed at understanding the molecular mechanisms underlying the decision between proliferation and differentiation during development, using Arabidopsis thaliana as the model system. Our current focus is to understand how nutrient availability influences stem cell division decisions in Arabidopsis meristem tissues. With the combination of genetic, molecular, and genomic approaches, we are trying to identify the gene network that regulates cell division in undifferentiated tissues. These studies will help answer how the stem cell populations are maintained in plants; and why plant tissues can easily dedifferentiate and regenerate. It can also contribute to the general understanding of stem cell behavior in other organisms.
 

Research Keywords

developmental biology, transcription regulation, plant stem cell regulation
 

Research Specialties

Aging and Development Biology, Cell and Developmental Biology, Genetics, Signal Transduction and Gene Regulation
 

Publications

Journal Article

Skylar, A., Wu, X. (2011). Regulation of meristem size by cytokinin signaling. J Integr Plant Biol.. Vol. 53, pp. 446-454.
Skylar, A., Sung, F., Hong, F., Chory, J., Wu, X. (2011). Metabolic sugar signal promotes Arabidopsis meristematic proliferation via G2. Developmental Biology. Vol. 351, pp. 82-89.
Yoo, S., Wu, X., Lee, J., Ahn, J. (2011). AGAMOUS-LIKE 6 is a floral promoter that negatively regulates the FLC/MAF clade genes and positively regulates FT in Arabidopsis. Plant Journal. Vol. 65, pp. 62-76.
Skylar, A., Wu, X. (2010). stimpy mutants have increased cytokinin sensitivity during dark germination. Plant Signaling & Behavior. Vol. 5 (11), pp. 1437-9.
Skylar, A., Hong, F., Chory, J., Weigel, D., Wu, X. (2010). STIMPY mediates cytokinin signaling during shoot meristem establishment in Arabidopsis seedlings. Development. Vol. 137, pp. 541-549.
Wu, X., Chory, J., Weigel, D. (2007). Combinations of WOX activities regulate tissue proliferation during Arabidopsis embryonic development. Developmental Biology. Vol. 309 (2), pp. 306-316.
Wu, X., Dabi, T., Weigel, D. (2005). Requirement of homeobox gene STIMPY for Arabidopsis meristem growth and maintenance. current biology/Cell Press. Vol. 15, pp. 436-440.
Palatnik, J. F., Allen, E., Wu, X., Schommer, C., Schwab, R., Carrington, J. C., Weigel, D. (2003). Control of leaf morphogenesis by microRNAs. Nature. Vol. 425, pp. 257-263.
Wu, X., Dinneny, J. R., Crawford, K. M., Rhee, Y., Citovsky, V., Zambryski, P. C., Weigel, D. (2003). Modes of intercellular transcription factor movement in the Arabidopsis apex. Development/The company of biologists. Vol. 130, pp. 3735-45.
Wu, X., Weigel, D., Wigge, P. A. (2002). Signaling in plants by intercellular RNA and protein movement. Genes & Development/cold spring harbor press. Vol. 16, pp. 151-158.
 

Honors and Awards

Life Sciences Research Foundation DOE-Energy Biosciences Research Fellow, 2001-2004  
 
 
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