University of Southern California
USC Dana and David Dornsife College of Letters, Arts and Sciences
Visit USC USC Dornsife HomepageAbout
About
Xuelin WuAssistant Professor of Biological SciencesContact Information E-mail: xuelinwu@usc.edu Phone: (213) 740-2165 Office: RRI 304B |
Education |
|
 Ph.D. Developmental Biology, New York University, New York, 2/2000
|
|
|
B.S. Molecular Biology, University of Science and Technology of China, China, 7/1993
|
|
Postdoctoral Training |
|
|
Postdoctoral Research Associate, The Salk Institute for Biological Studies, 05/15/2000-12/30/2006
|
|
Academic Appointment, Affiliation, and Employment History |
|
|
Assistant Professor, University of Southern California, 01/01/2007-
|
|
Description of Research |
|
Summary Statement of Research Interests |
|
| The research in my lab is aimed at understanding the molecular mechanisms underlying the decision between proliferation and differentiation during development, using Arabidopsis thaliana as the model system. Our current focus is to understand how nutrient availability influences stem cell division decisions in Arabidopsis meristem tissues. With the combination of genetic, molecular, and genomic approaches, we are trying to identify the gene network that regulates cell division in undifferentiated tissues. These studies will help answer how the stem cell populations are maintained in plants; and why plant tissues can easily dedifferentiate and regenerate. It can also contribute to the general understanding of stem cell behavior in other organisms. | |
Research Keywords |
|
| developmental biology, transcription regulation, plant stem cell regulation | |
Research Specialties |
|
| Aging and Development Biology, Cell and Developmental Biology, Genetics, Signal Transduction and Gene Regulation | |
Publications |
|
Journal Article |
|
|
Skylar, A., Wu, X.
(2011).
Regulation of meristem size by cytokinin signaling. J Integr Plant Biol..
Vol. 53, pp. 446-454.
|
|
|
Skylar, A., Sung, F., Hong, F., Chory, J., Wu, X.
(2011).
Metabolic sugar signal promotes Arabidopsis meristematic proliferation via G2. Developmental Biology.
Vol. 351, pp. 82-89.
|
|
|
Yoo, S., Wu, X., Lee, J., Ahn, J.
(2011).
AGAMOUS-LIKE 6 is a floral promoter that negatively regulates the FLC/MAF clade genes and positively regulates FT in Arabidopsis. Plant Journal.
Vol. 65, pp. 62-76.
|
|
|
Skylar, A., Wu, X.
(2010).
stimpy mutants have increased cytokinin sensitivity during dark germination. Plant Signaling & Behavior.
Vol. 5 (11), pp. 1437-9.
|
|
|
Skylar, A., Hong, F., Chory, J., Weigel, D., Wu, X.
(2010).
STIMPY mediates cytokinin signaling during shoot meristem establishment in Arabidopsis seedlings. Development.
Vol. 137, pp. 541-549.
|
|
|
Wu, X., Chory, J., Weigel, D.
(2007).
Combinations of WOX activities regulate tissue proliferation during Arabidopsis embryonic development. Developmental Biology.
Vol. 309 (2), pp. 306-316.
|
|
|
Wu, X., Dabi, T., Weigel, D.
(2005).
Requirement of homeobox gene STIMPY for Arabidopsis meristem growth and maintenance. current biology/Cell Press.
Vol. 15, pp. 436-440.
|
|
|
Palatnik, J. F., Allen, E., Wu, X., Schommer, C., Schwab, R., Carrington, J. C., Weigel, D.
(2003).
Control of leaf morphogenesis by microRNAs. Nature.
Vol. 425, pp. 257-263.
|
|
|
Wu, X., Dinneny, J. R., Crawford, K. M., Rhee, Y., Citovsky, V., Zambryski, P. C., Weigel, D.
(2003).
Modes of intercellular transcription factor movement in the Arabidopsis apex. Development/The company of biologists.
Vol. 130, pp. 3735-45.
|
|
|
Wu, X., Weigel, D., Wigge, P. A.
(2002).
Signaling in plants by intercellular RNA and protein movement. Genes & Development/cold spring harbor press.
Vol. 16, pp. 151-158.
|
|
Honors and Awards |
|
|
Life Sciences Research Foundation DOE-Energy Biosciences Research Fellow, 2001-2004
|
|
| Faculty may update their profile by visiting https://mydornsife.usc.edu. | |