University of Southern California
USC Dana and David Dornsife College of Letters, Arts and Sciences
Visit USC USC Dornsife HomepageAbout
About
Arshad Mahmood KhanAdjunct Assistant Professor of Biological SciencesContact Information E-mail: arshadk@usc.edu Phone: (213) 740-1501 Office: HNB 416 LINKS Personal PubMed Search Our research in the news USC article about our collaboration with the Donovan laboratory |
Education |
|
 Ph.D. Neuroscience, University of California, Riverside, 2002
|
|
|
M.S. Biochemistry, University of California, Riverside, 1996
|
|
Postdoctoral Training |
|
|
Posdoctoral Research Fellow, University of Southern California, 2004-05/31/2007
|
|
|
Postdoctoral Research Associate, University of Southern California, 2002-2004
|
|
Academic Appointment, Affiliation, and Employment History |
|
|
Research Assistant Professor, University of Southern California, 06/2007-
|
|
Description of Research |
|
Summary Statement of Research Interests |
|
| My research interests involve investigating the neurobiology of hypothalamic systems underlying ingestive behavior, energy balance, and neuroendocrine function. I am particularly interested in the interactions among neurotransmitter systems and the intracellular signaling mechanisms serving such systems. I also collaborate on neuroinformatics projects related to the modeling and management of neuroscientific data pertaining to these systems. As part of my interests in homeostatic mechanisms underlying energy balance, I also maintain an active research interest in the history of neurochemistry and thermodynamics. | |
Research Keywords |
|
| signal transduction, protein kinases, phosphorylation, homeostatic systems, neuroendocrine systems, neural basis of behavior, behavioral control systems, motivated behavior, feeding, hunger, energy balance, stress | |
Research Specialties |
|
| Neurochemistry / Neuroendocrinology / Functional neuroanatomy / Behavioral neuroscience / History of neuroscience / Neuroinformatics | |
Funded Research |
|
Contracts and Grants Awarded |
|
|
From Glucosensing Neurons to CRH Neuroendocrine Neurons: Circuits and Signals (NIDDK, NIH), Arshad M. Khan, $490,360, 08/01/2008-07/31/2012
|
|
Other Funded Research |
|
|
National Institute of Mental Health, NIH, NRSA Postdoctoral Fellowship, $130,000, 06/01/2004-05/31/2007
|
|
Affiliations with Research Centers, Labs, and Other Institutions |
|
|
Center for Neuro-Metabolic Interactions, University of Southern California
|
|
|
Laboratory of Alan G. Watts, University of Southern California, Collaborator
|
|
Conferences and Other Presentations |
|
Conference Presentations |
|
|
"Identification of putative microglial cells in the hypothalamus and thalamus that display phosphotyrosine-like immunoreactivity", American Society for Neurochemistry, Poster, Refereed Abstract, Santa Fe, New Mexico,
Spring
2010
|
|
|
"Noradrenergic Control of HPA Responses", 43rd Winter Conference on Brain Research, Roundtable/Panel, Abstract, Breckenridge, Colorado, WCBR, Invited,
Spring
2010
|
|
|
"Identification of a novel population of neurons displaying immunoreactive phosphorylated MAP kinases in the lateral hypothalamic area: histochemical relationship to the hypocretin/orexin system", Society for Neuroscience Annual Meeting, Poster, Abstract, Chicago, IL, NIDDK,
Fall
2009
|
|
|
"Identifying functional hypothalamic circuits using in vivo targeted toxin/drug injections and ex vivo slice imaging studies", Can New Tools Revolutionize Studies of Hypothalamic Circuits?, Poster, Abstract, Janelia Farm, Virginia, HHMI, Janelia Farm, Invited,
Fall
2009
|
|
|
"Visualizing Nature and Science: A Perspective from a Neuroscientist", Ninth Annual Department of Psychology Research Conference, Talk/Oral Presentation, University of California, Riverside, California, Department of Psychology, Invited,
Fall
2009
|
|
|
"A.V. Hill, war and British biophysics: Glimpses into the life of a scientist and a statesman", 14th Annual Meeting of the International Society for the History of the Neurosciences, Talk/Oral Presentation, Refereed Abstract, Charleston, South Carolina, ISHN,
Spring
2009
|
|
|
"A high spatial resolution immunocytochemical study of agouti-related peptide (AGRP) and hypocretin/orexin (ORX) within the lateral hypothalamic area", Annual Meeting of the Society for Neuroscience, Poster, Abstract, Washington, D.C., NINDS, NIMH,
Fall
2008
|
|
|
"From soldiering to soldering: restoring and re-staffing the biophysics unit at University College London after world war II", History section of the Annual Meeting of the Society for Neuroscience, Poster, Abstract, Washington, D.C., NIMH,
Fall
2008
|
|
|
"Stimulus-, circuit- and intracellular-level determinants of MAP kinase and CREB activation in parvicellular hypothalamic paraventricular neurons", Annual Meeting of the Society for Neuroscience, Poster, Abstract, Washington, D.C., NINDS,
Fall
2008
|
|
|
"Signal Transduction in CRH Neuroendocrine Neurons", American Neuroendocrine Society Annual Meeting, Symposium lecture, Abstract, San Rafael, California, NIMH, NINDS, Invited,
Spring
2008
|
|
|
"Measuring the energy of nervous impulses: the friendship (1911-1950) of Hill and Meyerhof and the emergence of neurochemistry.", 12th Annual Meeting of the International Society for the History of the Neurosciences, Talk and Accompanying Poster, Refereed UCLA, Los Angeles, CA, ISHN, NIMH,
Fall
2007
|
|
Other Presentations |
|
|
"When the Sweet Chariot Swings Low: Tracking Neuroendocrine Activation Following Hypoglycemia", Grand Rounds, Department of Neurology, Keck School of Medicine, Zilkha Neurogenetic Institute, University of Southern California,
Spring
2010
|
|
Other Research |
|
|
Archives Research - (August, 2007); Arranged Visit, Archives Centre, Churchill College,Cambridge, UK; A.V. Hill Papers.,
Fall
2007
|
|
|
Archives Research - (June, 2006); Arranged Visit, University of Pennsylvania Archives; Otto Meyerhof Papers.,
Spring
2006
|
|
Publications |
|
Book Chapter |
|
|
Stanley, B. G., Gillard, E. R., Khan, A. M.
(1998).
Physiological Controls of Eating and Body Weight. (Vol. 2). San Diego, CA: Encyclopedia of Mental Health / Academic Press Publishers.
|
|
Journal Article |
|
|
Khan, A. M.
(2009).
Nerve, muscle, blood, toil, tears and sweat: England’s pioneering biophysicist, soldier and statesman. The Journal of the History of the Neurosciences.
Vol. 18 (1), pp. 80-81, 98-105. PubMed Web Address
|
|
|
Gorton, L. M., Khan, A. M., Bohland, M., Sanchez-Watts, G., Donovan, C. M., Watts, A. G.
(2007).
A major role for the forebrain in mediating time-of-day differences in glucocorticoid counterregulatory responses to hypoglycemia. Endocrinology.
Vol. 148 (12), pp. 6026-6039.
|
|
|
Khan, A. M., Ponzio, T. A., Sanchez-Watts, G., Stanley, B. G., Hatton, G. I., Watts, A. G.
(2007).
Catecholaminergic control of MAP kinase signaling in paraventricular neuroendocrine neurons in vivo and in vitro: A proposed role during glycemic challenges. The Journal of Neuroscience.
Vol. 27 (27), pp. 7344-7360. PubMed Web Address
|
|
|
Khan, A. M., Hahn, J. D., Cheng, W., Watts, A. G., Burns, G. A.
(2006).
NeuroScholar's electronic laboratory notebook and its application to neuroendocrinology. Neuroinformatics.
Vol. 4 (2), pp. 139-160. PubMed Web Address
|
|
|
Watts, A. G., Khan, A. M., Sanchez-Watts, G., Salter, D., Neuner, C. M.
(2006).
Activation in neural networks controlling ingestive behaviors: What does it mean and how do we map and measure it?. Physiology & Behavior.
Vol. 89 (4), pp. 501-510. PubMed Web Address
|
|
|
Khan, A. M., Cheung, H. H., Gillard, E. R., Palarca, J. A., Welsbie, D. S., Gurd, J. W., Stanley, B. G.
(2004).
Lateral hypothalamic signaling mechanisms underlying feeding stimulation: Differential contributions of Src family tyrosine kinases to feeding triggered either by NMDA injection or by food deprivation. The Journal of Neuroscience.
Vol. 24, pp. 10603-10615. PubMed Web Address
|
|
|
Khan, A. M., Watts, A. G.
(2004).
Intravenous 2-deoxy-D-glucose injection rapidly elevates levels of the phosphorylated forms of p44/42 mitogen activated protein kinases (ERK1/2) in rat hypothalamic parvicellular paraventricular neurons. Endocrinology.
Vol. 145 (1), pp. 351-359. PubMed Web Address
|
|
|
Burns, G. A., Khan, A. M., Ghandeharizadeh, S., O'Neill, M. A., Chen, Y.
(2003).
Practical tools and approaches for the construction of knowledge models from the neuroscientific literature. Neuroinformatics.
Vol. 1 (1), pp. 81-109.
|
|
|
Khan, A. M., Stanley, B. G., Bozzetti, L., Chin, C., Stivers, C., Curras-Collazo, M. C.
(2000).
N-methyl-D-aspartate receptor subunit NR2B is widely expressed throughout the rat diencephalon: An immunohistochemical study. The Journal of Comparative Neurology.
Vol. 428, pp. 428-449. PubMed Web Address
|
|
|
Khan, A. M., Curras, M. C., Jamal, F. A., Turkowski, C. A., Goel, R. K., Dao, J., Gillard, E. R., Stanley, B. G.
(1999).
Lateral hypothalamic NMDA receptor subunits NR2A and/or NR2B mediate eating: Immunochemical/behavioral evidence. American Journal of Physiology.
Vol. 276, pp. R880-R891.
|
|
|
Gillard, E. R., Khan, A. M., Mouradi, B., Nalamwar, O., Stanley, B. G.
(1998).
Eating induced by perifornical cAMP is behaviorally selective and involves protein kinase activity. American Journal of Physiology.
Vol. 275, pp. R647-R653.
|
|
|
Miyata, S., Khan, A. M., Hatton, G. I.
(1998).
Colocalization of calretinin and calbindin-D28k with oxytocin and vasopressin in rat supraoptic nucleus neurons: A quantitative study. Brain Research.
Vol. 785, pp. 178-182. PubMed Web Address
|
|
|
Gillard, E. R., Khan, A. M., Grewal, R. S., Mouradi, B., Wolfsohn, S. D., Stanley, B. G.
(1998).
The second messenger cyclic AMP elicits eating by an anatomically specific action in the perifornical hypothalamus. The Journal of Neuroscience.
Vol. 18, pp. 2646-2652.
|
|
|
Gillard, E. R., Khan, A. M., Haq, A. U., Grewal, R. S., Mouradi, B., Stanley, B. G.
(1997).
Stimulation of eating by the second messenger cAMP in the perifornical and lateral hypothalamus. American Journal of Physiology.
Vol. 273, pp. R107-R112.
|
|
|
Visscher, P. K., Khan, A. M.
(1995).
A trap for bees remaining after swarm and colony removal. American Bee Journal.
Vol. 135, pp. 567-572.
|
|
|
Visscher, P. K., Vetter, R. S., Khan, A. M.
(1995).
The use of insecticidal soap in abatement of honey bee swarms. Bee Science.
Vol. 3, pp. 179-184.
|
|
Guest Lectures in Courses |
|
|
BISC 221L: Advanced General Biology: Cell Biology & Physiology. Topics of guest lectures taught over Spring semester (2003-2010): glycolysis, cellular respiration, photosynthesis, membranes, mitosis, nervous systems, metabolism, meiosis and sexual life cycles, Mendelian genetics, synapse structure and function, ionic basis of resting membrane potential, synaptic and action potentials, cellular communication, animal reproduction, human fertilization & reproduction, cells & organelles, reproductive endocrinology and parturition, 2003-2010
|
|
|
BISC 230L: Brain, Mind, and Machines: Topics in Neuroscience Guest lectures on the electrophysiology of neurons, principles of action potential generation and synaptic transmission,
Spring
2010
|
|
|
Neuro 499: Special Topics in Neuroscience Guest lecture: "Interoceptive Signals of the CNS: An Introduction",
Spring
2010
|
|
|
BISC 462: Diabetes, Obesity and the Brain Guest lecture and group discussion on the topic of "Circadian rhythms, arousal mechanisms and metabolism",
Fall
2009
|
|
|
BISC 421: Neurobiology. Topics of guest lectures: synaptic release, B. Katz’s experiments with the squid giant synapse,
Fall
2003
|
|
Honors and Awards |
|
|
Travel Fellowship Award - 43rd Winter Conference on Brain Research, Breckenridge, CO, 2009-2010
|
|
Service to the University |
|
Other Service to the University |
|
|
Invited Panelist - informal discussion with Neuroscience Graduate Forum on seeking postdoctoral appointments,
Spring
2008
|
|
|
Invited Speaker and Panelist, Symposium on "Academic Grant Writing for the Life Sciences"; hosted by the USC Neuroscience Graduate Forum
,
Spring
2006
|
|
Service to the Profession |
|
Committees |
|
|
Member, Membership Committee, American Society of Neurochemistry, 03/2010-03/2014
|
|
Conferences Organized |
|
|
Co-organizer, Spring 2003 Workshop on the Behaving Brain, Hedco Neurosciences Building, A weekly workshop with a total of seventeen speakers from UC Irvine, UCLA, UC Riverside, USC and Caltech.
,
Spring
2003
|
|
Professional Memberships |
|
|
American Society for Neurochemistry, 2010-
|
|
|
International Society for the History of the Neurosciences, 2008-
|
|
|
American Society for Neuroendocrinology, 2005-
|
|
|
American Association for the Advancement of Science, 1996-
|
|
|
Society for Neuroscience, 1996-
|
|
| Faculty may update their profile by visiting https://mydornsife.usc.edu. | |